62 items (Drosophila ananassae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF21687	BZIP domain-containing protein. (215 aa)
	DanaGF23086	Uncharacterized protein. (199 aa)
	DanaGF23075	Uncharacterized protein. (188 aa)
	DanaGF20661	FERM domain-containing protein. (1451 aa)
	DanaGF21137	Uncharacterized protein. (488 aa)
	DanaGF24066	Uncharacterized protein. (478 aa)
	DanaGF23311	Uncharacterized protein. (1087 aa)
	DanaGF20920	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (364 aa)
	DanaGF21249	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (452 aa)
	DanaGF20269	FERM domain-containing protein. (635 aa)
	DanaGF14124	Uncharacterized protein, isoform A. (512 aa)
	DanaGF15022	Uncharacterized protein. (187 aa)
	DanaGF15021	Uncharacterized protein. (5188 aa)
	DanaGF14977	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (713 aa)
	DanaGF14938	Uncharacterized protein. (252 aa)
	DanaGF14591	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (245 aa)
	DanaGF13818	Uncharacterized protein, isoform A. (850 aa)
	DanaGF13179	Uncharacterized protein. (654 aa)
	DanaGF12347	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (545 aa)
	DanaGF13647	Uncharacterized protein. (148 aa)
	DanaGF11827	Uncharacterized protein, isoform A. (210 aa)
	DanaGF13065	Phosphatidylinositol 3-kinase catalytic subunit type 3. (945 aa)
	DanaGF11948	Transcription factor. (444 aa)
	DanaGF11995	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (332 aa)
	DanaGF11997	Uncharacterized protein, isoform A; Belongs to the BI1 family. (323 aa)
	DanaGF11429	Uncharacterized protein. (1482 aa)
	DanaGF19818	Uncharacterized protein, isoform A. (309 aa)
	DanaGF13352	Uncharacterized protein, isoform A. (264 aa)
	DanaGF11577	Uncharacterized protein. (1255 aa)
	DanaGF12143	RING-type domain-containing protein. (424 aa)
	DanaGF24126	Uncharacterized protein, isoform A. (208 aa)
	DanaGF10826	Uncharacterized protein. (435 aa)
	DanaGF10314	Uncharacterized protein. (135 aa)
	DanaGF10822	Uncharacterized protein. (128 aa)
	DanaGF23636	Uncharacterized protein. (134 aa)
	DanaGF10726	Uncharacterized protein. (125 aa)
	DanaGF24859	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)
	DanaGF24399	Uncharacterized protein. (856 aa)
	DanaGF10584	Uncharacterized protein; Belongs to the peptidase C14A family. (450 aa)
	DanaGF23870	Uncharacterized protein. (287 aa)
	DanaGF10527	Uncharacterized protein. (457 aa)
	DanaGF17921	Homeobox domain-containing protein. (564 aa)
	DanaGF17891	Uncharacterized protein. (999 aa)
	DanaGF17810	Uncharacterized protein, isoform A. (802 aa)
	DanaGF17792	Homeobox domain-containing protein. (582 aa)
	DanaGF18349	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (534 aa)
	DanaGF18269	Uncharacterized protein. (608 aa)
	DanaGF18796	Uncharacterized protein, isoform A. (822 aa)
	DanaGF18785	Uncharacterized protein; Belongs to the BI1 family. (263 aa)
	DanaGF16244	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (246 aa)
	DanaGF17609	Uncharacterized protein, isoform A. (535 aa)
	Kibra	Protein kibra; Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. Kibra acts synergistically along with Ex and Mer to regulate the Hippo signalin [...] (1271 aa)
	DanaGF18064	Uncharacterized protein, isoform A. (234 aa)
	HtrA2	Serine protease HTRA2, mitochondrial; Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase- independent and serine protease activity-dependent mechanism. Can antagonize antiapoptotic activity of th by directly inducing the degradation of th (By similarity); Belongs to the peptidase S1C family. (426 aa)
	DanaGF18586	Uncharacterized protein. (3563 aa)
	DanaGF11135	Uncharacterized protein, isoform B; Belongs to the AAA ATPase family. (827 aa)
	DanaGF10866	Uncharacterized protein, isoform B. (875 aa)
	DanaGF22459	Uncharacterized protein, isoform C. (657 aa)
	DanaGF25100	Uncharacterized protein. (442 aa)
	DanaGF19599	Uncharacterized protein. (2712 aa)
	DanaGF20158	Uncharacterized protein. (219 aa)
	DanaGF19157	Protein kinase domain-containing protein. (701 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF10314	DanaGF16244	B3M945	B3LYA1	Uncharacterized protein.	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family.	0.861
DanaGF10584	DanaGF10822	B3M583	B3M8A9	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.948
DanaGF10584	DanaGF10826	B3M583	B3M8B5	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.981
DanaGF10584	DanaGF11429	B3M583	B3MD75	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.999
DanaGF10584	DanaGF13179	B3M583	B3MHA7	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.488
DanaGF10584	DanaGF13818	B3M583	B3MJ68	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein, isoform A.	0.483
DanaGF10584	DanaGF18064	B3M583	B3LVL4	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein, isoform A.	0.833
DanaGF10584	DanaGF24066	B3M583	B3MU33	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.437
DanaGF10584	HtrA2	B3M583	B3LVG7	Uncharacterized protein; Belongs to the peptidase C14A family.	Serine protease HTRA2, mitochondrial; Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase- independent and serine protease activity-dependent mechanism. Can antagonize antiapoptotic activity of th by directly inducing the degradation of th (By similarity); Belongs to the peptidase S1C family.	0.597
DanaGF10822	DanaGF10584	B3M8A9	B3M583	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.948
DanaGF10822	DanaGF11429	B3M8A9	B3MD75	Uncharacterized protein.	Uncharacterized protein.	0.654
DanaGF10822	DanaGF13818	B3M8A9	B3MJ68	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.478
DanaGF10826	DanaGF10584	B3M8B5	B3M583	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.981
DanaGF10826	DanaGF11429	B3M8B5	B3MD75	Uncharacterized protein.	Uncharacterized protein.	0.430
DanaGF10826	DanaGF13179	B3M8B5	B3MHA7	Uncharacterized protein.	Uncharacterized protein.	0.430
DanaGF10866	DanaGF13065	A0A0P8YJ01	B3MFH3	Uncharacterized protein, isoform B.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.998
DanaGF10866	DanaGF17609	A0A0P8YJ01	B3LXA9	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform A.	0.469
DanaGF10866	DanaGF18349	A0A0P8YJ01	B3M0F1	Uncharacterized protein, isoform B.	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.999
DanaGF10866	DanaGF24126	A0A0P8YJ01	B3M9Q9	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform A.	0.594
DanaGF11135	DanaGF14591	A0A0P9C0U8	B3MJE5	Uncharacterized protein, isoform B; Belongs to the AAA ATPase family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.941