51 items (Drosophila ananassae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF21923	Uncharacterized protein. (5255 aa)
	DanaGF19146	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1234 aa)
	DanaGF20730	CG6036-PA. (366 aa)
	DanaGF25100	Uncharacterized protein. (442 aa)
	DanaGF14574	Uncharacterized protein, isoform B. (757 aa)
	DanaGF19249	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (235 aa)
	DanaGF26852	Non-specific serine/threonine protein kinase. (903 aa)
	DanaGF10060	Uncharacterized protein, isoform B. (572 aa)
	DanaGF22303	Uncharacterized protein, isoform D. (222 aa)
	DanaGF22237	Uncharacterized protein, isoform C. (1095 aa)
	DanaGF17501	Arrestin_C domain-containing protein. (485 aa)
	DanaGF16939	JmjC domain-containing protein. (439 aa)
	DanaGF16395	Uncharacterized protein. (186 aa)
	DanaGF19876	Uncharacterized protein. (217 aa)
	DanaGF17460	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (456 aa)
	DanaGF18132	Uncharacterized protein, isoform A. (348 aa)
	DanaGF16724	Uncharacterized protein. (491 aa)
	DanaGF16102	LIM domain-containing protein. (348 aa)
	DanaGF16080	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	DanaGF16047	ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (178 aa)
	DanaGF10527	Uncharacterized protein. (457 aa)
	DanaGF23912	Uncharacterized protein, isoform A. (930 aa)
	DanaGF24443	Uncharacterized protein, isoform A. (618 aa)
	DanaGF24399	Uncharacterized protein. (856 aa)
	Urm1	Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as Jafrac1, Ciao1, Eip71CD and GILT1. The thiocarboxylated form serves as substrate [...] (101 aa)
	DanaGF10661	Uncharacterized protein, isoform A. (444 aa)
	DanaGF10184	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (482 aa)
	DanaGF23258	N-acetyltransferase domain-containing protein. (199 aa)
	DanaGF21287	Uncharacterized protein. (506 aa)
	DanaGF21176	Uncharacterized protein, isoform B; Belongs to the SKP1 family. (163 aa)
	DanaGF20412	Uncharacterized protein. (374 aa)
	DanaGF10220	Ubiquitin carboxyl-terminal hydrolase. (826 aa)
	DanaGF10784	Uncharacterized protein. (552 aa)
	DanaGF10268	Uncharacterized protein. (591 aa)
	DanaGF10914	Uncharacterized protein. (934 aa)
	DanaGF11927	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
	DanaGF13513	WH1 domain-containing protein. (534 aa)
	DanaGF11773	Uncharacterized protein. (1375 aa)
	DanaGF11159	Uncharacterized protein. (624 aa)
	DanaGF14357	Uncharacterized protein, isoform A. (998 aa)
	DanaGF15135	UBR-type domain-containing protein. (5344 aa)
	DanaGF14121	Uncharacterized protein, isoform A. (2704 aa)
	DanaGF23353	Uncharacterized protein, isoform B. (375 aa)
	DanaGF23378	Uncharacterized protein. (175 aa)
	DanaGF23379	Uncharacterized protein. (176 aa)
	DanaGF20820	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (276 aa)
	DanaGF20766	Uncharacterized protein. (763 aa)
	DanaGF20651	Uncharacterized protein. (698 aa)
	DanaGF21702	Uncharacterized protein. (283 aa)
	DanaGF19359	Uncharacterized protein. (1899 aa)
	DanaGF19539	Serine/threonine-protein phosphatase. (303 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF10060	DanaGF23353	A0A0P8XTZ8	A0A0N8NYZ8	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform B.	0.554
DanaGF10184	DanaGF16080	B3M6T5	B3M150	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.677
DanaGF10268	DanaGF10527	B3M831	B3M4I1	Uncharacterized protein.	Uncharacterized protein.	0.654
DanaGF10268	DanaGF13513	B3M831	B3ME26	Uncharacterized protein.	WH1 domain-containing protein.	0.410
DanaGF10268	DanaGF19539	B3M831	B3MXY0	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.406
DanaGF10268	DanaGF24399	B3M831	B3M5I4	Uncharacterized protein.	Uncharacterized protein.	0.984
DanaGF10268	DanaGF25100	B3M831	B3N297	Uncharacterized protein.	Uncharacterized protein.	0.984
DanaGF10527	DanaGF10268	B3M4I1	B3M831	Uncharacterized protein.	Uncharacterized protein.	0.654
DanaGF10527	DanaGF10784	B3M4I1	B3M7P3	Uncharacterized protein.	Uncharacterized protein.	0.410
DanaGF10661	DanaGF16724	B3M632	B3LZ87	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.686
DanaGF10784	DanaGF10527	B3M7P3	B3M4I1	Uncharacterized protein.	Uncharacterized protein.	0.410
DanaGF10784	DanaGF11773	B3M7P3	B3MGN7	Uncharacterized protein.	Uncharacterized protein.	0.623
DanaGF10914	DanaGF19539	B3MA06	B3MXY0	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.994
DanaGF11773	DanaGF10784	B3MGN7	B3M7P3	Uncharacterized protein.	Uncharacterized protein.	0.623
DanaGF11927	DanaGF20820	B3MDV9	B3MUA4	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.998
DanaGF13513	DanaGF10268	B3ME26	B3M831	WH1 domain-containing protein.	Uncharacterized protein.	0.410
DanaGF13513	DanaGF19146	B3ME26	B3N0S7	WH1 domain-containing protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.400
DanaGF13513	DanaGF22303	B3ME26	A0A0P8Y8F7	WH1 domain-containing protein.	Uncharacterized protein, isoform D.	0.639
DanaGF14121	DanaGF15135	B3MPQ1	B3MMX5	Uncharacterized protein, isoform A.	UBR-type domain-containing protein.	0.734
DanaGF14574	DanaGF23912	A0A0P8XF23	B3M4I5	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform A.	0.968