33 items (Drosophila ananassae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF24880	Uncharacterized protein, isoform A. (841 aa)
	DanaGF25310	Rap-GAP domain-containing protein. (1828 aa)
	DanaGF17967	Uncharacterized protein, isoform A. (471 aa)
	DanaGF16105	Uncharacterized protein. (1107 aa)
	DanaGF18327	Uncharacterized protein, isoform A; Belongs to the PI3/PI4-kinase family. (1099 aa)
	DanaGF16155	Uncharacterized protein. (602 aa)
	DanaGF18269	Uncharacterized protein. (608 aa)
	Kibra	Protein kibra; Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. Kibra acts synergistically along with Ex and Mer to regulate the Hippo signalin [...] (1271 aa)
	DanaGF20860	Protein kinase domain-containing protein. (972 aa)
	DanaGF21273	WD_REPEATS_REGION domain-containing protein. (343 aa)
	DanaGF20482	Uncharacterized protein, isoform A. (1037 aa)
	DanaGF20738	Uncharacterized protein, isoform B. (2276 aa)
	DanaGF20269	FERM domain-containing protein. (635 aa)
	DanaGF14124	Uncharacterized protein, isoform A. (512 aa)
	chico	Insulin receptor substrate 1; Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit. May mediate the control of various cellular processes by insulin-like peptides. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains. Involved in control of cell proliferation, cell size, and body and organ growth throughout development. Also has a role in a signaling pathway controlling the physiological response required to endure periods of low nutrient conditions. Insulin/insulin-like growth factor (IGF) signal [...] (940 aa)
	DanaGF15587	Uncharacterized protein. (3491 aa)
	DanaGF15021	Uncharacterized protein. (5188 aa)
	DanaGF14535	Uncharacterized protein, isoform C. (1296 aa)
	DanaGF14065	Nitric oxide synthase; Produces nitric oxide (NO). (1356 aa)
	DanaGF23311	Uncharacterized protein. (1087 aa)
	DanaGF20661	FERM domain-containing protein. (1451 aa)
	DanaGF21986	Uncharacterized protein. (512 aa)
	DanaGF21884	Uncharacterized protein. (556 aa)
	DanaGF19606	BHLH domain-containing protein. (711 aa)
	DanaGF24504	Uncharacterized protein, isoform C. (5588 aa)
	DanaGF17811	Uncharacterized protein, isoform B. (2121 aa)
	DanaGF18271	Uncharacterized protein, isoform B. (502 aa)
	DanaGF11095	Uncharacterized protein. (731 aa)
	DanaGF17645	Uncharacterized protein, isoform B. (2207 aa)
	DanaGF24678	IlGF domain-containing protein. (137 aa)
	DanaGF24757	Uncharacterized protein, isoform A. (1332 aa)
	DanaGF10826	Uncharacterized protein. (435 aa)
	DanaGF24301	Uncharacterized protein, isoform A. (742 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF11095	DanaGF14535	B3MIJ1	B3MK56	Uncharacterized protein.	Uncharacterized protein, isoform C.	0.979
DanaGF11095	DanaGF18327	B3MIJ1	B3M0A8	Uncharacterized protein.	Uncharacterized protein, isoform A; Belongs to the PI3/PI4-kinase family.	0.538
DanaGF11095	DanaGF20482	B3MIJ1	B3MQQ7	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.513
DanaGF14065	DanaGF16105	B3MJW2	B3M0M0	Nitric oxide synthase; Produces nitric oxide (NO).	Uncharacterized protein.	0.506
DanaGF14065	DanaGF16155	B3MJW2	B3LZY7	Nitric oxide synthase; Produces nitric oxide (NO).	Uncharacterized protein.	0.603
DanaGF14124	DanaGF16105	B3MPP1	B3M0M0	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.830
DanaGF14124	DanaGF16155	B3MPP1	B3LZY7	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.988
DanaGF14124	DanaGF17811	B3MPP1	A0A0P8XY38	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform B.	0.892
DanaGF14124	DanaGF18327	B3MPP1	B3M0A8	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A; Belongs to the PI3/PI4-kinase family.	0.988
DanaGF14124	DanaGF19606	B3MPP1	B3N1U8	Uncharacterized protein, isoform A.	BHLH domain-containing protein.	0.493
DanaGF14124	DanaGF23311	B3MPP1	B3MT80	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.450
DanaGF14124	DanaGF24880	B3MPP1	B3M6L6	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.798
DanaGF14124	DanaGF25310	B3MPP1	B3M4P1	Uncharacterized protein, isoform A.	Rap-GAP domain-containing protein.	0.887
DanaGF14124	Kibra	B3MPP1	B3LWS4	Uncharacterized protein, isoform A.	Protein kibra; Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. Kibra acts synergistically along with Ex and Mer to regulate the Hippo signalin [...]	0.660
DanaGF14124	chico	B3MPP1	B3MPN6	Uncharacterized protein, isoform A.	Insulin receptor substrate 1; Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit. May mediate the control of various cellular processes by insulin-like peptides. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains. Involved in control of cell proliferation, cell size, and body and organ growth throughout development. Also has a role in a signaling pathway controlling the physiological response required to endure periods of low nutrient conditions. Insulin/insulin-like growth factor (IGF) signal [...]	0.751
DanaGF14535	DanaGF11095	B3MK56	B3MIJ1	Uncharacterized protein, isoform C.	Uncharacterized protein.	0.979
DanaGF15021	DanaGF20661	B3MLP3	B3MUH3	Uncharacterized protein.	FERM domain-containing protein.	0.953
DanaGF15021	DanaGF23311	B3MLP3	B3MT80	Uncharacterized protein.	Uncharacterized protein.	0.810
DanaGF16105	DanaGF14065	B3M0M0	B3MJW2	Uncharacterized protein.	Nitric oxide synthase; Produces nitric oxide (NO).	0.506
DanaGF16105	DanaGF14124	B3M0M0	B3MPP1	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.830