(18 nodes) Imaginal disc-derived male genitalia morphogenesis network (Drosophila ananassae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF11026	Uncharacterized protein, isoform A. (718 aa)
	DanaGF12370	Uncharacterized protein. (174 aa)
	DanaGF12648	Uncharacterized protein. (430 aa)
	otk	Tyrosine-protein kinase-like otk; Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system. Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage. Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons (By similarity). (1037 aa)
	DanaGF14089	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1014 aa)
	DanaGF15270	Receptor protein-tyrosine kinase. (1578 aa)
	DanaGF15280	Uncharacterized protein, isoform A. (219 aa)
	DanaGF14126	Mitogen-activated protein kinase. (376 aa)
	DanaGF21297	Integrin beta; Belongs to the integrin beta chain family. (864 aa)
	DanaGF20874	Protein kinase domain-containing protein. (1170 aa)
	DanaGF23109	Uncharacterized protein, isoform A. (690 aa)
	DanaGF24454	Uncharacterized protein, isoform A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1037 aa)
	Fas2	Fasciclin 2, isoform C. (883 aa)
	DanaGF15271	Receptor protein-tyrosine kinase. (1183 aa)
	DanaGF16318	VWFC domain-containing protein. (2684 aa)
	DanaGF16724	Uncharacterized protein. (491 aa)
	DanaGF10821	Uncharacterized protein. (65 aa)
	DanaGF19599	Uncharacterized protein. (2712 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF10821	DanaGF16724	B3M8A8	B3LZ87	Uncharacterized protein.	Uncharacterized protein.	0.629
DanaGF12370	DanaGF15280	B3MFV6	B3MPJ2	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.603
DanaGF14126	DanaGF16724	B3MPN7	B3LZ87	Mitogen-activated protein kinase.	Uncharacterized protein.	0.999
DanaGF14126	DanaGF20874	B3MPN7	B3MS41	Mitogen-activated protein kinase.	Protein kinase domain-containing protein.	0.999
DanaGF15270	DanaGF21297	B3MPH3	B3MRJ4	Receptor protein-tyrosine kinase.	Integrin beta; Belongs to the integrin beta chain family.	0.400
DanaGF15271	DanaGF21297	A0A0P8XFF2	B3MRJ4	Receptor protein-tyrosine kinase.	Integrin beta; Belongs to the integrin beta chain family.	0.400
DanaGF15280	DanaGF12370	B3MPJ2	B3MFV6	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.603
DanaGF15280	DanaGF23109	B3MPJ2	B3MV76	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.598
DanaGF16724	DanaGF10821	B3LZ87	B3M8A8	Uncharacterized protein.	Uncharacterized protein.	0.629
DanaGF16724	DanaGF14126	B3LZ87	B3MPN7	Uncharacterized protein.	Mitogen-activated protein kinase.	0.999
DanaGF16724	DanaGF20874	B3LZ87	B3MS41	Uncharacterized protein.	Protein kinase domain-containing protein.	0.956
DanaGF16724	DanaGF21297	B3LZ87	B3MRJ4	Uncharacterized protein.	Integrin beta; Belongs to the integrin beta chain family.	0.412
DanaGF19599	DanaGF21297	B3N1W3	B3MRJ4	Uncharacterized protein.	Integrin beta; Belongs to the integrin beta chain family.	0.428
DanaGF19599	otk	B3N1W3	B3MH43	Uncharacterized protein.	Tyrosine-protein kinase-like otk; Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system. Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage. Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons (By similarity).	0.461
DanaGF20874	DanaGF14126	B3MS41	B3MPN7	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.999
DanaGF20874	DanaGF16724	B3MS41	B3LZ87	Protein kinase domain-containing protein.	Uncharacterized protein.	0.956
DanaGF21297	DanaGF15270	B3MRJ4	B3MPH3	Integrin beta; Belongs to the integrin beta chain family.	Receptor protein-tyrosine kinase.	0.400
DanaGF21297	DanaGF15271	B3MRJ4	A0A0P8XFF2	Integrin beta; Belongs to the integrin beta chain family.	Receptor protein-tyrosine kinase.	0.400
DanaGF21297	DanaGF16724	B3MRJ4	B3LZ87	Integrin beta; Belongs to the integrin beta chain family.	Uncharacterized protein.	0.412
DanaGF21297	DanaGF19599	B3MRJ4	B3N1W3	Integrin beta; Belongs to the integrin beta chain family.	Uncharacterized protein.	0.428