(50 nodes) Response to growth factor network (Drosophila ananassae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF13635	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (575 aa)
	DanaGF13942	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
	DanaGF20585	Uncharacterized protein, isoform B. (629 aa)
	DanaGF20577	Mothers against decapentaplegic homolog. (581 aa)
	DanaGF11678	Uncharacterized protein, isoform H. (1301 aa)
	DanaGF27276	Uncharacterized protein. (1054 aa)
	DanaGF18012	Uncharacterized protein, isoform C. (735 aa)
	DanaGF17516	Uncharacterized protein, isoform A. (1233 aa)
	DanaGF17542	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
	DanaGF17357	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (722 aa)
	DanaGF16803	Uncharacterized protein, isoform A. (731 aa)
	DanaGF18247	Fibroblast growth factor receptor. (734 aa)
	DanaGF17706	Uncharacterized protein. (952 aa)
	Ras85D	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
	DanaGF17083	Mothers against decapentaplegic homolog. (568 aa)
	DanaGF10553	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1086 aa)
	DanaGF10082	Uncharacterized protein, isoform A. (2260 aa)
	DanaGF24409	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (913 aa)
	DanaGF23695	TIR domain-containing protein. (1524 aa)
	DanaGF24148	Uncharacterized protein, isoform A. (1323 aa)
	DanaGF10882	UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (476 aa)
	DanaGF23539	Uncharacterized protein. (1052 aa)
	DanaGF24647	Uncharacterized protein. (411 aa)
	DanaGF11457	Uncharacterized protein. (733 aa)
	DanaGF11456	Uncharacterized protein. (771 aa)
	DanaGF13508	Uncharacterized protein. (548 aa)
	DanaGF12511	TGF_BETA_2 domain-containing protein. (454 aa)
	DanaGF12526	Uncharacterized protein. (2598 aa)
	DanaGF11787	Uncharacterized protein. (1556 aa)
	DanaGF11743	TIR domain-containing protein; Belongs to the Toll-like receptor family. (1384 aa)
	DanaGF11180	Uncharacterized protein. (211 aa)
	DanaGF11739	TIR domain-containing protein; Belongs to the Toll-like receptor family. (1455 aa)
	DanaGF12221	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (627 aa)
	DanaGF15305	Uncharacterized protein. (747 aa)
	DanaGF14461	Small ubiquitin-related modifier. (91 aa)
	DanaGF19714	TGF_BETA_2 domain-containing protein. (402 aa)
	DanaGF14981	Uncharacterized protein, isoform A. (593 aa)
	DanaGF15519	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (562 aa)
	DanaGF14259	Uncharacterized protein. (1587 aa)
	DanaGF14676	Uncharacterized protein, isoform D. (452 aa)
	DanaGF20979	Mothers against decapentaplegic homolog. (471 aa)
	DanaGF21460	Uncharacterized protein. (803 aa)
	DanaGF22977	Ig-like domain-containing protein. (858 aa)
	DanaGF22974	Mothers against decapentaplegic homolog. (770 aa)
	DanaGF24729	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
	DanaGF22442	UBIQUITIN_CONJUGAT_2 domain-containing protein. (164 aa)
	DanaGF22213	Uncharacterized protein. (727 aa)
	DanaGF19094	Uncharacterized protein. (458 aa)
	Dsor1	Downstream of raf1, isoform A; Belongs to the protein kinase superfamily. (396 aa)
	DanaGF12294	Uncharacterized protein, isoform A. (585 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF10082	DanaGF24148	B3M5D3	B3M972	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.536
DanaGF10082	Ras85D	B3M5D3	B3M185	Uncharacterized protein, isoform A.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.726
DanaGF10553	DanaGF11180	B3M4U9	B3MGZ3	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.727
DanaGF10882	DanaGF23539	B3M9F6	B3M9Y1	UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	Uncharacterized protein.	0.806
DanaGF11180	DanaGF10553	B3MGZ3	B3M4U9	Uncharacterized protein.	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.727
DanaGF11180	DanaGF11456	B3MGZ3	B3MCW0	Uncharacterized protein.	Uncharacterized protein.	0.540
DanaGF11180	DanaGF11457	B3MGZ3	B3MCV6	Uncharacterized protein.	Uncharacterized protein.	0.540
DanaGF11180	DanaGF13942	B3MGZ3	A0A0N8P175	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.411
DanaGF11180	DanaGF14259	B3MGZ3	B3MN28	Uncharacterized protein.	Uncharacterized protein.	0.998
DanaGF11180	DanaGF14676	B3MGZ3	B3MP16	Uncharacterized protein.	Uncharacterized protein, isoform D.	0.937
DanaGF11180	DanaGF17357	B3MGZ3	B3LXR9	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.711
DanaGF11180	DanaGF17516	B3MGZ3	B3LVX7	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.408
DanaGF11180	DanaGF17706	B3MGZ3	B3LZH5	Uncharacterized protein.	Uncharacterized protein.	0.616
DanaGF11180	DanaGF18247	B3MGZ3	B3LYP9	Uncharacterized protein.	Fibroblast growth factor receptor.	0.591
DanaGF11180	DanaGF21460	B3MGZ3	B3MSF7	Uncharacterized protein.	Uncharacterized protein.	0.990
DanaGF11180	DanaGF22213	B3MGZ3	B3MYV0	Uncharacterized protein.	Uncharacterized protein.	0.695
DanaGF11180	DanaGF24647	B3MGZ3	B3MAQ8	Uncharacterized protein.	Uncharacterized protein.	0.993
DanaGF11180	DanaGF27276	B3MGZ3	A0A0P8Y939	Uncharacterized protein.	Uncharacterized protein.	0.591
DanaGF11180	Dsor1	B3MGZ3	B3MZP8	Uncharacterized protein.	Downstream of raf1, isoform A; Belongs to the protein kinase superfamily.	0.728
DanaGF11180	Ras85D	B3MGZ3	B3M185	Uncharacterized protein.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.906