(36 nodes) Plasma membrane signaling receptor complex network (Drosophila ananassae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF22287	Uncharacterized protein, isoform A; Belongs to the integrin alpha chain family. (1396 aa)
	DanaGF22443	Uncharacterized protein, isoform C. (811 aa)
	DanaGF19012	G_PROTEIN_RECEP_F3_4 domain-containing protein. (701 aa)
	DanaGF21713	Uncharacterized protein. (1056 aa)
	DanaGF20156	Neur_chan_memb domain-containing protein. (255 aa)
	DanaGF20712	Uncharacterized protein. (600 aa)
	DanaGF20752	Uncharacterized protein, isoform A. (567 aa)
	DanaGF21655	Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (193 aa)
	DanaGF16969	Uncharacterized protein, isoform A. (1234 aa)
	DanaGF17542	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
	Nmdar1	Glutamate [NMDA] receptor subunit 1; NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. Plays a role in associative learning and in long-term memory consolidation (By similarity). (994 aa)
	DanaGF18325	Uncharacterized protein. (903 aa)
	DanaGF18326	Uncharacterized protein. (883 aa)
	DanaGF10464	PBPe domain-containing protein. (906 aa)
	DanaGF24409	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (913 aa)
	DanaGF10860	Uncharacterized protein. (1123 aa)
	DanaGF23545	Uncharacterized protein. (988 aa)
	DanaGF12221	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (627 aa)
	DanaGF14903	G_PROTEIN_RECEP_F3_4 domain-containing protein. (842 aa)
	DanaGF15519	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (562 aa)
	DanaGF15030	Uncharacterized protein, isoform A; Belongs to the G-protein coupled receptor 3 family. (1320 aa)
	DanaGF15073	Uncharacterized protein. (942 aa)
	DanaGF15572	Uncharacterized protein. (906 aa)
	DanaGF15573	Uncharacterized protein. (1035 aa)
	DanaGF14279	Uncharacterized protein. (789 aa)
	DanaGF21297	Integrin beta; Belongs to the integrin beta chain family. (864 aa)
	DanaGF21362	Uncharacterized protein, isoform A. (1089 aa)
	DanaGF20867	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1218 aa)
	DanaGF21041	Integrin beta; Belongs to the integrin beta chain family. (802 aa)
	DanaGF23103	Uncharacterized protein, isoform B. (491 aa)
	DanaGF22568	Uncharacterized protein, isoform C. (845 aa)
	DanaGF13028	Uncharacterized protein, isoform B; Belongs to the integrin alpha chain family. (1115 aa)
	DanaGF21872	Uncharacterized protein, isoform C. (523 aa)
	DanaGF17811	Uncharacterized protein, isoform B. (2121 aa)
	DanaGF26869	Protein kinase domain-containing protein. (270 aa)
	DanaGF13635	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (575 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF10860	DanaGF21362	B3M9B2	B3MRX1	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.404
DanaGF10860	DanaGF21713	B3M9B2	B3N0I5	Uncharacterized protein.	Uncharacterized protein.	0.414
DanaGF10860	DanaGF23103	B3M9B2	A0A0P9BLU4	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.512
DanaGF10860	Nmdar1	B3M9B2	B3LZ39	Uncharacterized protein.	Glutamate [NMDA] receptor subunit 1; NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. Plays a role in associative learning and in long-term memory consolidation (By similarity).	0.520
DanaGF12221	DanaGF17542	B3MI97	B3LW28	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.980
DanaGF12221	DanaGF24409	B3MI97	B3M5G3	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.865
DanaGF13028	DanaGF20867	A0A0P8YB75	B3MS54	Uncharacterized protein, isoform B; Belongs to the integrin alpha chain family.	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	0.628
DanaGF13028	DanaGF21041	A0A0P8YB75	B3MU64	Uncharacterized protein, isoform B; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.979
DanaGF13028	DanaGF21297	A0A0P8YB75	B3MRJ4	Uncharacterized protein, isoform B; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.984
DanaGF13028	DanaGF22287	A0A0P8YB75	B3MWB8	Uncharacterized protein, isoform B; Belongs to the integrin alpha chain family.	Uncharacterized protein, isoform A; Belongs to the integrin alpha chain family.	0.464
DanaGF13635	DanaGF15519	A0A0N8P0G2	B3MLM4	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.962
DanaGF13635	DanaGF17542	A0A0N8P0G2	B3LW28	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.924
DanaGF13635	DanaGF24409	A0A0N8P0G2	B3M5G3	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.978
DanaGF14279	DanaGF21872	B3MMS1	A0A0P8Y5B5	Uncharacterized protein.	Uncharacterized protein, isoform C.	0.497
DanaGF14279	DanaGF23103	B3MMS1	A0A0P9BLU4	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.428
DanaGF14903	DanaGF15030	B3MLC7	B3MLQ9	G_PROTEIN_RECEP_F3_4 domain-containing protein.	Uncharacterized protein, isoform A; Belongs to the G-protein coupled receptor 3 family.	0.998
DanaGF14903	DanaGF16969	B3MLC7	B3LVH2	G_PROTEIN_RECEP_F3_4 domain-containing protein.	Uncharacterized protein, isoform A.	0.999
DanaGF14903	DanaGF19012	B3MLC7	B3N053	G_PROTEIN_RECEP_F3_4 domain-containing protein.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.447
DanaGF15030	DanaGF14903	B3MLQ9	B3MLC7	Uncharacterized protein, isoform A; Belongs to the G-protein coupled receptor 3 family.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.998
DanaGF15030	DanaGF16969	B3MLQ9	B3LVH2	Uncharacterized protein, isoform A; Belongs to the G-protein coupled receptor 3 family.	Uncharacterized protein, isoform A.	0.913