(40 nodes) Transport vesicle membrane network (Drosophila ananassae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF24073	t-SNARE coiled-coil homology domain-containing protein. (230 aa)
	flower	Calcium channel flower; A calcium channel that regulates synaptic endocytosis and hence couples exo- with endocytosis. Required in the nervous system and necessary in photoreceptor cells (By similarity). (195 aa)
	GF10347	Vacuolar ATPase assembly integral membrane protein VMA21 homolog; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family. (106 aa)
	DanaGF23679	Uncharacterized protein. (196 aa)
	wls	Protein wntless; A segment polarity gene required for wingless (wg)-dependent patterning processes, acting in both wg-sending cells and wg-target cells. In non-neuronal cells wls directs wg secretion. The wls traffic loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, and involves clathrin-mediated endocytosis and the retromer complex (a conserved protein complex consisting of Vps35 and Vps26). In neuronal cells (the larval motorneuron NMJ), the wg signal moves across the synapse via the release of wls-containing exos [...] (562 aa)
	DanaGF16536	Uncharacterized protein, isoform A; Belongs to the adaptor complexes medium subunit family. (426 aa)
	DanaGF17454	Uncharacterized protein. (981 aa)
	DanaGF18079	Uncharacterized protein, isoform A; Belongs to the small GTPase superfamily. SAR1 family. (193 aa)
	DanaGF18026	Uncharacterized protein. (212 aa)
	DanaGF16993	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (363 aa)
	DanaGF17577	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (780 aa)
	DanaGF21377	Uncharacterized protein, isoform B. (2110 aa)
	DanaGF26473	MFS domain-containing protein. (580 aa)
	DanaGF11179	Uncharacterized protein, isoform B. (652 aa)
	DanaGF15020	Uncharacterized protein, isoform B. (836 aa)
	DanaGF20158	Uncharacterized protein. (219 aa)
	DanaGF20595	Uncharacterized protein, isoform A; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (724 aa)
	DanaGF19013	Uncharacterized protein, isoform B. (3012 aa)
	DanaGF21592	Uncharacterized protein. (352 aa)
	DanaGF13871	Uncharacterized protein, isoform A. (474 aa)
	DanaGF19194	AP-1 complex subunit gamma. (979 aa)
	DanaGF19375	Uncharacterized protein, isoform B; Belongs to the CDC50/LEM3 family. (358 aa)
	DanaGF20561	Uncharacterized protein, isoform A. (177 aa)
	DanaGF21117	Uncharacterized protein, isoform A. (1301 aa)
	DanaGF22878	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (804 aa)
	DanaGF20826	Uncharacterized protein. (659 aa)
	DanaGF20843	MFS domain-containing protein. (639 aa)
	DanaGF15690	Uncharacterized protein, isoform A. (610 aa)
	DanaGF15689	Uncharacterized protein, isoform A. (822 aa)
	DanaGF15046	ABC transporter domain-containing protein. (700 aa)
	DanaGF15508	Uncharacterized protein, isoform A. (640 aa)
	DanaGF15295	Uncharacterized protein. (1262 aa)
	DanaGF13825	Uncharacterized protein, isoform A. (1283 aa)
	DanaGF13767	Uncharacterized protein. (199 aa)
	DanaGF11162	Synaptogyrin. (240 aa)
	DanaGF12386	Uncharacterized protein, isoform A. (1246 aa)
	DanaGF12527	Uncharacterized protein, isoform A. (327 aa)
	DanaGF12899	Uncharacterized protein, isoform A. (553 aa)
	DanaGF11571	Uncharacterized protein. (1167 aa)
	DanaGF24019	Uncharacterized protein, isoform A. (190 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF11162	DanaGF12899	B3MHE7	B3MCY7	Synaptogyrin.	Uncharacterized protein, isoform A.	0.418
DanaGF11162	DanaGF13871	B3MHE7	B3N1B0	Synaptogyrin.	Uncharacterized protein, isoform A.	0.604
DanaGF11162	DanaGF15508	B3MHE7	B3MLJ2	Synaptogyrin.	Uncharacterized protein, isoform A.	0.413
DanaGF11162	DanaGF17454	B3MHE7	B3LW11	Synaptogyrin.	Uncharacterized protein.	0.432
DanaGF11179	DanaGF12899	A0A0P8XRC4	B3MCY7	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform A.	0.596
DanaGF11179	DanaGF13871	A0A0P8XRC4	B3N1B0	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform A.	0.920
DanaGF11179	DanaGF15508	A0A0P8XRC4	B3MLJ2	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform A.	0.802
DanaGF11179	DanaGF17454	A0A0P8XRC4	B3LW11	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.586
DanaGF11179	DanaGF19013	A0A0P8XRC4	A0A0N8NZJ9	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform B.	0.686
DanaGF11179	DanaGF22878	A0A0P8XRC4	B3MTF8	Uncharacterized protein, isoform B.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.414
DanaGF11179	DanaGF24019	A0A0P8XRC4	B3MB08	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform A.	0.684
DanaGF11571	DanaGF12386	B3MBK8	B3MFD8	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.995
DanaGF11571	DanaGF15295	B3MBK8	B3MJA3	Uncharacterized protein.	Uncharacterized protein.	0.993
DanaGF11571	DanaGF16993	B3MBK8	B3LV15	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	0.995
DanaGF11571	DanaGF17577	B3MBK8	A0A0P8YCW4	Uncharacterized protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.999
DanaGF11571	DanaGF18079	B3MBK8	B3LVN7	Uncharacterized protein.	Uncharacterized protein, isoform A; Belongs to the small GTPase superfamily. SAR1 family.	0.990
DanaGF11571	DanaGF19194	B3MBK8	B3MZK4	Uncharacterized protein.	AP-1 complex subunit gamma.	0.401
DanaGF11571	DanaGF21377	B3MBK8	A0A0P8Y085	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.982
DanaGF12386	DanaGF11571	B3MFD8	B3MBK8	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.995
DanaGF12386	DanaGF13767	B3MFD8	B3MI46	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.801