95 items (Drosophila ananassae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF25178	SAM domain-containing protein. (252 aa)
	DanaGF10392	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (497 aa)
	DanaGF25039	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (175 aa)
	DanaGF24802	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (109 aa)
	DanaGF24839	Uncharacterized protein. (871 aa)
	DanaGF10195	Uncharacterized protein. (1122 aa)
	DanaGF10194	Uncharacterized protein, isoform D. (1096 aa)
	DanaGF10193	Uncharacterized protein. (1053 aa)
	DanaGF10192	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2728 aa)
	DanaGF23720	Uncharacterized protein, isoform A. (1134 aa)
	DanaGF10705	Uncharacterized protein, isoform A. (420 aa)
	DanaGF10653	Uncharacterized protein. (1131 aa)
	DanaGF23807	Uncharacterized protein. (545 aa)
	DanaGF24409	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (913 aa)
	DanaGF10598	Uncharacterized protein. (803 aa)
	DanaGF25310	Rap-GAP domain-containing protein. (1828 aa)
	DanaGF24509	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (487 aa)
	DanaGF23902	Uncharacterized protein, isoform A; Belongs to the cyclin family. (1139 aa)
	DanaGF18478	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (574 aa)
	DanaGF18898	PWWP domain-containing protein. (249 aa)
	DanaGF18349	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (534 aa)
	DanaGF16155	Uncharacterized protein. (602 aa)
	DanaGF16690	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. (314 aa)
	DanaGF17710	Uncharacterized protein, isoform A. (1169 aa)
	DanaGF18269	Uncharacterized protein. (608 aa)
	DanaGF17624	Protein kinase domain-containing protein. (1357 aa)
	DanaGF17356	Uncharacterized protein. (1078 aa)
	DanaGF16842	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (98 aa)
	DanaGF18125	Uncharacterized protein; Belongs to the cyclin family. (267 aa)
	DanaGF16341	Uncharacterized protein, isoform A. (1354 aa)
	DanaGF17542	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
	DanaGF18045	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (295 aa)
	DanaGF22322	Uncharacterized protein, isoform C. (1537 aa)
	DanaGF19112	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1361 aa)
	DanaGF19666	RPOLD domain-containing protein. (275 aa)
	DanaGF23161	Uncharacterized protein, isoform C. (1407 aa)
	DanaGF12632	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (968 aa)
	DanaGF20738	Uncharacterized protein, isoform B. (2276 aa)
	DanaGF14405	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1096 aa)
	DanaGF10866	Uncharacterized protein, isoform B. (875 aa)
	DanaGF27626	Cyclin_C domain-containing protein. (175 aa)
	DanaGF24022	Uncharacterized protein, isoform B. (231 aa)
	DanaGF11313	Protein kinase domain-containing protein. (714 aa)
	DanaGF17811	Uncharacterized protein, isoform B. (2121 aa)
	DanaGF15214	Uncharacterized protein, isoform B. (942 aa)
	DanaGF23314	Uncharacterized protein, isoform B; Belongs to the protein kinase superfamily. (379 aa)
	DanaGF26908	Uncharacterized protein, isoform A. (766 aa)
	DanaGF19365	Uncharacterized protein, isoform C. (1149 aa)
	DanaGF11791	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2763 aa)
	DanaGF15930	Uncharacterized protein. (1200 aa)
	DanaGF23396	CYCLIN domain-containing protein; Belongs to the cyclin family. (402 aa)
	DanaGF22718	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (75 aa)
	DanaGF22626	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
	DanaGF23061	Uncharacterized protein, isoform B. (122 aa)
	DanaGF20823	Uncharacterized protein, isoform C. (599 aa)
	DanaGF20951	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (352 aa)
	DanaGF20974	Uncharacterized protein. (476 aa)
	DanaGF21274	Uncharacterized protein. (305 aa)
	DanaGF21264	Protein kinase domain-containing protein. (285 aa)
	DanaGF14115	Cyclin-dependent kinase 5 activator. (448 aa)
	DanaGF15742	SERPIN domain-containing protein; Belongs to the serpin family. (388 aa)
	DanaGF15714	Uncharacterized protein. (73 aa)
	DanaGF14221	Deacetylase sirtuin-type domain-containing protein. (835 aa)
	DanaGF14724	Uncharacterized protein. (240 aa)
	DanaGF14725	Uncharacterized protein. (240 aa)
	DanaGF19687	Uncharacterized protein. (286 aa)
	DanaGF14727	Uncharacterized protein. (298 aa)
	DanaGF14734	Uncharacterized protein. (329 aa)
	DanaGF14738	Protein kinase domain-containing protein. (458 aa)
	DanaGF14406	Uncharacterized protein. (113 aa)
	DanaGF14977	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (713 aa)
	DanaGF14974	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (699 aa)
	DanaGF15386	Uncharacterized protein; Belongs to the cyclin family. (402 aa)
	DanaGF14103	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
	DanaGF11091	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (320 aa)
	DanaGF13242	Uncharacterized protein, isoform A. (840 aa)
	DanaGF12221	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (627 aa)
	DanaGF15984	Protein kinase domain-containing protein. (732 aa)
	DanaGF21760	Uncharacterized protein; Belongs to the ATP-dependent DNA ligase family. (924 aa)
	DanaGF21904	Gamma-tubulin complex component. (1077 aa)
	DanaGF12245	SERPIN domain-containing protein; Belongs to the serpin family. (394 aa)
	plu	Plutonium. (175 aa)
	DanaGF12341	Transcription elongation factor SPT5. (1081 aa)
	DanaGF13086	TIR domain-containing protein. (537 aa)
	DanaGF13065	Phosphatidylinositol 3-kinase catalytic subunit type 3. (945 aa)
	DanaGF11326	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (514 aa)
	DanaGF13008	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (403 aa)
	DanaGF11908	Uncharacterized protein. (1367 aa)
	DanaGF13498	Uncharacterized protein. (587 aa)
	DanaGF11937	BZIP domain-containing protein. (514 aa)
	DanaGF11940	Helicase ATP-binding domain-containing protein. (768 aa)
	DanaGF11396	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. (326 aa)
	DanaGF12951	AMPKBI domain-containing protein. (330 aa)
	DanaGF11005	General transcription factor IIH subunit. (422 aa)
	DanaGF25171	CYCLIN domain-containing protein; Belongs to the cyclin family. (324 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF10192	DanaGF13008	B3M6V0	B3MEC6	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.410
DanaGF10192	DanaGF18125	B3M6V0	B3LWQ7	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein; Belongs to the cyclin family.	0.995
DanaGF10192	DanaGF19666	B3M6V0	A0A0P9BPH7	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	RPOLD domain-containing protein.	0.603
DanaGF10392	DanaGF10598	B3MAD1	B3M5C1	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Uncharacterized protein.	0.999
DanaGF10392	DanaGF11005	B3MAD1	B3MBA0	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	General transcription factor IIH subunit.	0.999
DanaGF10392	DanaGF11091	B3MAD1	B3MIK0	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.998
DanaGF10392	DanaGF11940	B3MAD1	B3MDT0	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Helicase ATP-binding domain-containing protein.	0.998
DanaGF10392	DanaGF12341	B3MAD1	B3MGG2	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Transcription elongation factor SPT5.	0.875
DanaGF10392	DanaGF13008	B3MAD1	B3MEC6	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.423
DanaGF10392	DanaGF13498	B3MAD1	B3MDZ8	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Uncharacterized protein.	0.999
DanaGF10392	DanaGF14734	B3MAD1	B3MN97	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Uncharacterized protein.	0.999
DanaGF10392	DanaGF15386	B3MAD1	B3MK78	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Uncharacterized protein; Belongs to the cyclin family.	0.715
DanaGF10392	DanaGF15714	B3MAD1	B3MP88	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Uncharacterized protein.	0.999
DanaGF10392	DanaGF18045	B3MAD1	B3LVH3	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.925
DanaGF10392	DanaGF19666	B3MAD1	A0A0P9BPH7	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	RPOLD domain-containing protein.	0.979
DanaGF10392	DanaGF20951	B3MAD1	B3MRQ7	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.966
DanaGF10392	DanaGF21760	B3MAD1	B3N0A3	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Uncharacterized protein; Belongs to the ATP-dependent DNA ligase family.	0.462
DanaGF10392	DanaGF23902	B3MAD1	B3M4K3	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Uncharacterized protein, isoform A; Belongs to the cyclin family.	0.694
DanaGF10392	DanaGF25171	B3MAD1	B3MAT4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.993
DanaGF10598	DanaGF10392	B3M5C1	B3MAD1	Uncharacterized protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.999