58 items (Drosophila ananassae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF11091	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (320 aa)
	DanaGF18949	HDAg domain-containing protein. (1255 aa)
	DanaGF16578	Uncharacterized protein. (537 aa)
	DanaGF23902	Uncharacterized protein, isoform A; Belongs to the cyclin family. (1139 aa)
	DanaGF24452	TPR_REGION domain-containing protein. (1137 aa)
	DanaGF10598	Uncharacterized protein. (803 aa)
	DanaGF10157	RRM domain-containing protein. (281 aa)
	DanaGF24952	Uncharacterized protein, isoform A. (1122 aa)
	DanaGF10841	Uncharacterized protein, isoform A. (1110 aa)
	DanaGF10392	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (497 aa)
	DanaGF25165	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (149 aa)
	DanaGF25171	CYCLIN domain-containing protein; Belongs to the cyclin family. (324 aa)
	DanaGF11005	General transcription factor IIH subunit. (422 aa)
	DanaGF11564	TPR_REGION domain-containing protein. (1112 aa)
	DanaGF13399	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (116 aa)
	DanaGF11940	Helicase ATP-binding domain-containing protein. (768 aa)
	DanaGF13498	Uncharacterized protein. (587 aa)
	DanaGF12460	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (728 aa)
	DanaGF13008	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (403 aa)
	DanaGF12445	Uncharacterized protein. (210 aa)
	DanaGF11885	Plus3 domain-containing protein. (781 aa)
	DanaGF11242	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (902 aa)
	DanaGF12606	Uncharacterized protein, isoform A; Belongs to the SKP1 family. (117 aa)
	DanaGF12341	Transcription elongation factor SPT5. (1081 aa)
	DanaGF11166	Uncharacterized protein. (351 aa)
	Eaf	Ell-associated factor Eaf; Promotes transcriptional elongation by Su(Tpl)/ELL. Essential for development (By similarity); Belongs to the EAF family. (503 aa)
	DanaGF17851	WD_REPEATS_REGION domain-containing protein. (332 aa)
	DanaGF15386	Uncharacterized protein; Belongs to the cyclin family. (402 aa)
	lilli	AF4/FMR2 family member lilli; Has a role in transcriptional regulation. Acts in parallel with the Ras/MAPK and the PI3K/PKB pathways in the control of cell identity and cellular growth. Essential for regulation of the cytoskeleton and cell growth but not for cell proliferation or growth rate. Required specifically for the microtubule-based basal transport of lipid droplets. Plays a partially redundant function downstream of Raf in cell fate specification in the developing eye. Pair-rule protein that regulates embryonic cellularization, gastrulation and segmentation (By similarity); Bel [...] (1587 aa)
	DanaGF15561	Uncharacterized protein. (315 aa)
	DanaGF15107	RNA_pol_L_2 domain-containing protein. (117 aa)
	DanaGF14734	Uncharacterized protein. (329 aa)
	DanaGF15714	Uncharacterized protein. (73 aa)
	DanaGF20366	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1889 aa)
	DanaGF20387	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1870 aa)
	DanaGF21119	Uncharacterized protein. (591 aa)
	DanaGF20951	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (352 aa)
	DanaGF21518	Uncharacterized protein, isoform B. (549 aa)
	DanaGF22456	Plus3 domain-containing protein. (295 aa)
	DanaGF11507	AHD domain-containing protein. (949 aa)
	DanaGF11496	Uncharacterized protein. (155 aa)
	DanaGF19568	Uncharacterized protein. (578 aa)
	DanaGF11824	Uncharacterized protein. (173 aa)
	DanaGF19061	TFIIS N-terminal domain-containing protein. (752 aa)
	DanaGF26439	Uncharacterized protein. (328 aa)
	DanaGF12628	Uncharacterized protein. (57 aa)
	DanaGF19666	RPOLD domain-containing protein. (275 aa)
	DanaGF16986	TFIIS N-terminal domain-containing protein. (648 aa)
	DanaGF16336	Uncharacterized protein, isoform A. (694 aa)
	DanaGF17437	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (281 aa)
	DanaGF17638	Uncharacterized protein. (503 aa)
	DanaGF16238	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1176 aa)
	DanaGF17248	Uncharacterized protein. (131 aa)
	DanaGF16163	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (129 aa)
	DanaGF17223	Uncharacterized protein. (67 aa)
	DanaGF18332	Ubiquitin-like domain-containing protein. (118 aa)
	DanaGF18359	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (577 aa)
	DanaGF18911	Uncharacterized protein. (548 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF10157	DanaGF10598	B3M688	B3M5C1	RRM domain-containing protein.	Uncharacterized protein.	0.519
DanaGF10157	DanaGF10841	B3M688	B3M8T5	RRM domain-containing protein.	Uncharacterized protein, isoform A.	0.783
DanaGF10157	DanaGF11005	B3M688	B3MBA0	RRM domain-containing protein.	General transcription factor IIH subunit.	0.492
DanaGF10157	DanaGF11166	B3M688	B3MHD7	RRM domain-containing protein.	Uncharacterized protein.	0.429
DanaGF10157	DanaGF11242	B3M688	B3MG83	RRM domain-containing protein.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.695
DanaGF10157	DanaGF11496	B3M688	B3MX76	RRM domain-containing protein.	Uncharacterized protein.	0.500
DanaGF10157	DanaGF11507	B3M688	B3MX75	RRM domain-containing protein.	AHD domain-containing protein.	0.500
DanaGF10157	DanaGF11824	B3M688	B3MXA0	RRM domain-containing protein.	Uncharacterized protein.	0.825
DanaGF10157	DanaGF12341	B3M688	B3MGG2	RRM domain-containing protein.	Transcription elongation factor SPT5.	0.985
DanaGF10157	DanaGF12445	B3M688	B3MEP0	RRM domain-containing protein.	Uncharacterized protein.	0.863
DanaGF10157	DanaGF12460	B3M688	B3ME79	RRM domain-containing protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.779
DanaGF10157	DanaGF12606	B3M688	B3MGF9	RRM domain-containing protein.	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	0.709
DanaGF10157	DanaGF12628	B3M688	A0A0P9ACH2	RRM domain-containing protein.	Uncharacterized protein.	0.857
DanaGF10157	DanaGF13008	B3M688	B3MEC6	RRM domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.953
DanaGF10157	DanaGF13399	B3M688	B3MCU0	RRM domain-containing protein.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.965
DanaGF10157	DanaGF14734	B3M688	B3MN97	RRM domain-containing protein.	Uncharacterized protein.	0.491
DanaGF10157	DanaGF15107	B3M688	B3MMI8	RRM domain-containing protein.	RNA_pol_L_2 domain-containing protein.	0.821
DanaGF10157	DanaGF15386	B3M688	B3MK78	RRM domain-containing protein.	Uncharacterized protein; Belongs to the cyclin family.	0.862
DanaGF10157	DanaGF15561	B3M688	B3MMA2	RRM domain-containing protein.	Uncharacterized protein.	0.422
DanaGF10157	DanaGF16163	B3M688	B3LZX4	RRM domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.827