26 items (Drosophila grimshawi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DgriGH14000	GH14000. (598 aa)
	DgriGH15267	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (138 aa)
	DgriGH16382	GH16382; Belongs to the small Tim family. (92 aa)
	DgriGH17079	GH17079; Belongs to the GroES chaperonin family. (104 aa)
	DgriGH19719	GH19719. (541 aa)
	DgriGH21004	GH21004. (536 aa)
	GH20828	Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer; Belongs to the SDHAF2 family. (147 aa)
	DgriGH20634	Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (206 aa)
	DgriGH20407	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5298 aa)
	DgriGH10210	GH10210; Belongs to the small Tim family. (82 aa)
	DgriGH11666	T-complex protein 1 subunit delta. (533 aa)
	DgriGH22450	GH22450; Belongs to the GroES chaperonin family. (102 aa)
	DgriGH18252	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (501 aa)
	DgriGH18159	T-complex protein 1 subunit gamma. (544 aa)
	DgriGH18653	Tubulin-specific chaperone A; Belongs to the TBCA family. (110 aa)
	DgriGH19579	Calreticulin. (403 aa)
	DgriGH11842	GH11842; Belongs to the small Tim family. (85 aa)
	DgriGH12396	GH12396. (533 aa)
	DgriGH12183	GH12183; Belongs to the small Tim family. (88 aa)
	DgriGH24729	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (200 aa)
	DgriGH24158	GH24158. (532 aa)
	DgriGH18443	GH18443. (557 aa)
	DgriGH24010	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (196 aa)
	DgriGH17336	Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. Belongs to the PSMG2 family. (247 aa)
	DgriGH22689	GH22689. (546 aa)
	DgriGH23157	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (215 aa)

Your Current Organism:

Drosophila grimshawi

NCBI taxonomy Id: 7222
Other names: D. grimshawi, Idiomyia grimshawi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DgriGH10210	DgriGH12183	B4JBH8	B4JJT8	GH10210; Belongs to the small Tim family.	GH12183; Belongs to the small Tim family.	0.982
DgriGH11666	DgriGH12396	B4JCN1	B4JIV9	T-complex protein 1 subunit delta.	GH12396.	0.999
DgriGH11666	DgriGH15267	B4JCN1	B4IX17	T-complex protein 1 subunit delta.	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.	0.863
DgriGH11666	DgriGH17079	B4JCN1	B4J027	T-complex protein 1 subunit delta.	GH17079; Belongs to the GroES chaperonin family.	0.732
DgriGH11666	DgriGH18159	B4JCN1	B4JG86	T-complex protein 1 subunit delta.	T-complex protein 1 subunit gamma.	0.993
DgriGH11666	DgriGH18252	B4JCN1	B4JFJ6	T-complex protein 1 subunit delta.	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.999
DgriGH11666	DgriGH18443	B4JCN1	B4JSB6	T-complex protein 1 subunit delta.	GH18443.	0.999
DgriGH11666	DgriGH18653	B4JCN1	B4JH66	T-complex protein 1 subunit delta.	Tubulin-specific chaperone A; Belongs to the TBCA family.	0.595
DgriGH11666	DgriGH19579	B4JCN1	B4JHQ4	T-complex protein 1 subunit delta.	Calreticulin.	0.576
DgriGH11666	DgriGH19719	B4JCN1	B4J4M7	T-complex protein 1 subunit delta.	GH19719.	0.999
DgriGH11666	DgriGH21004	B4JCN1	B4J534	T-complex protein 1 subunit delta.	GH21004.	0.993
DgriGH11666	DgriGH22450	B4JCN1	B4K155	T-complex protein 1 subunit delta.	GH22450; Belongs to the GroES chaperonin family.	0.732
DgriGH11666	DgriGH22689	B4JCN1	B4JVE5	T-complex protein 1 subunit delta.	GH22689.	0.999
DgriGH11666	DgriGH23157	B4JCN1	B4JVP2	T-complex protein 1 subunit delta.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.673
DgriGH11666	DgriGH24010	B4JCN1	B4JTK4	T-complex protein 1 subunit delta.	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family.	0.900
DgriGH11666	DgriGH24158	B4JCN1	B4JND6	T-complex protein 1 subunit delta.	GH24158.	0.993
DgriGH11666	DgriGH24729	B4JCN1	B4JN13	T-complex protein 1 subunit delta.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.673
DgriGH12183	DgriGH10210	B4JJT8	B4JBH8	GH12183; Belongs to the small Tim family.	GH10210; Belongs to the small Tim family.	0.982
DgriGH12183	DgriGH16382	B4JJT8	B4IZA8	GH12183; Belongs to the small Tim family.	GH16382; Belongs to the small Tim family.	0.982
DgriGH12183	DgriGH17079	B4JJT8	B4J027	GH12183; Belongs to the small Tim family.	GH17079; Belongs to the GroES chaperonin family.	0.556