25 items (Drosophila grimshawi) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	DgriGH18477	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (452 aa)
	DgriGH15740	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (410 aa)
	DgriGH16382	GH16382; Belongs to the small Tim family. (92 aa)
	Sgf11-1	SAGA-associated factor 11 homolog 1; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Binds independently on SAGA to promoters in an RNA- dependent manner. Bi [...] (211 aa)
	Sgf11-2	SAGA-associated factor 11 homolog 2; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Binds independently on SAGA to promoters in an RNA- dependent manner. Bi [...] (211 aa)
	DgriGH20846	Nuclear pore complex protein Nup75; Functions as a component of the nuclear pore complex (NPC). (679 aa)
	DgriGH21806	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (99 aa)
	DgriGH10210	GH10210; Belongs to the small Tim family. (82 aa)
	DgriGH10458	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (576 aa)
	DgriGH10449	GH10449. (145 aa)
	DgriGH11309	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (890 aa)
	DgriGH18990	Nuclear pore protein. (797 aa)
	e(y)2	Enhancer of yellow 2 transcription factor; Involved in mRNA export coupled transcription activation by association with both the AMEX and the SAGA complexes. The SAGA complex is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Involved in t [...] (102 aa)
	DgriGH11842	GH11842; Belongs to the small Tim family. (85 aa)
	DgriGH12183	GH12183; Belongs to the small Tim family. (88 aa)
	DgriGH11983	Translocating chain-associated membrane protein; Belongs to the TRAM family. (372 aa)
	DgriGH11910	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (340 aa)
	e(y)2-2	Enhancer of yellow 2 transcription factor; Involved in mRNA export coupled transcription activation by association with both the AMEX and the SAGA complexes. The SAGA complex is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Involved in t [...] (94 aa)
	DgriGH24494	GH24494. (95 aa)
	DgriGH24034	GH24034. (123 aa)
	DgriGH13249	GH13249. (476 aa)
	DgriGH22682	GH22682. (92 aa)
	DgriGH17674	Nuclear pore protein. (845 aa)
	DgriGH17760	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (407 aa)
	DgriGH17531	GH17531. (145 aa)

Your Current Organism:

Drosophila grimshawi

NCBI taxonomy Id: 7222
Other names: D. grimshawi, Idiomyia grimshawi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DgriGH10210	DgriGH12183	B4JBH8	B4JJT8	GH10210; Belongs to the small Tim family.	GH12183; Belongs to the small Tim family.	0.982
DgriGH10210	DgriGH18477	B4JBH8	B4JII9	GH10210; Belongs to the small Tim family.	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	0.576
DgriGH10210	DgriGH22682	B4JBH8	B4JVF8	GH10210; Belongs to the small Tim family.	GH22682.	0.977
DgriGH10210	DgriGH24034	B4JBH8	B4JMF2	GH10210; Belongs to the small Tim family.	GH24034.	0.817
DgriGH10210	DgriGH24494	B4JBH8	B4JLP9	GH10210; Belongs to the small Tim family.	GH24494.	0.839
DgriGH10458	DgriGH12183	B4JE03	B4JJT8	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	GH12183; Belongs to the small Tim family.	0.405
DgriGH10458	DgriGH15740	B4JE03	B4IYK0	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.413
DgriGH10458	DgriGH18477	B4JE03	B4JII9	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	0.710
DgriGH10458	DgriGH22682	B4JE03	B4JVF8	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	GH22682.	0.549
DgriGH11309	DgriGH11910	B4JE54	B4JL90	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family.	0.982
DgriGH11309	DgriGH17674	B4JE54	B4JWX6	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nuclear pore protein.	0.976
DgriGH11309	DgriGH18990	B4JE54	B4JHU7	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nuclear pore protein.	0.976
DgriGH11309	DgriGH20846	B4JE54	B4J5I7	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nuclear pore complex protein Nup75; Functions as a component of the nuclear pore complex (NPC).	0.999
DgriGH11910	DgriGH11309	B4JL90	B4JE54	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family.	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	0.982
DgriGH11910	DgriGH17674	B4JL90	B4JWX6	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family.	Nuclear pore protein.	0.963
DgriGH11910	DgriGH18990	B4JL90	B4JHU7	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family.	Nuclear pore protein.	0.963
DgriGH11910	DgriGH20846	B4JL90	B4J5I7	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family.	Nuclear pore complex protein Nup75; Functions as a component of the nuclear pore complex (NPC).	0.967
DgriGH11983	DgriGH13249	B4JKV7	B4JQ75	Translocating chain-associated membrane protein; Belongs to the TRAM family.	GH13249.	0.476
DgriGH12183	DgriGH10210	B4JJT8	B4JBH8	GH12183; Belongs to the small Tim family.	GH10210; Belongs to the small Tim family.	0.982
DgriGH12183	DgriGH10458	B4JJT8	B4JE03	GH12183; Belongs to the small Tim family.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.405