34 items (Drosophila grimshawi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DgriGH14704	GH14704. (419 aa)
	DgriGH16965	GH16965. (414 aa)
	DgriGH17093	Dihydrolipoyl dehydrogenase. (504 aa)
	DgriGH14994	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (517 aa)
	DgriGH14418	GH14418; Belongs to the aldehyde dehydrogenase family. (540 aa)
	DgriGH17185	GH17185; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (469 aa)
	DgriGH15449	GH15449; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
	DgriGH14768	GH14768; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (503 aa)
	DgriGH20865	GH20865; Belongs to the enoyl-CoA hydratase/isomerase family. (293 aa)
	DgriGH20195	GH20195; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa)
	DgriGH21754	GH21754. (581 aa)
	DgriGH19963	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (463 aa)
	DgriGH19800	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (322 aa)
	DgriGH11058	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family. (785 aa)
	DgriGH11066	GH11066. (617 aa)
	DgriGH11301	GH11301; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
	DgriGH18279	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (439 aa)
	DgriGH18965	GH18965; Belongs to the aldehyde dehydrogenase family. (485 aa)
	DgriGH24496	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (445 aa)
	DgriGH24555	GH24555. (520 aa)
	DgriGH24642	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (460 aa)
	DgriGH24264	GH24264. (551 aa)
	DgriGH24783	GH24783; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (255 aa)
	DgriGH13348	GH13348. (322 aa)
	DgriGH13343	GH13343. (306 aa)
	DgriGH13324	GH13324; Belongs to the aldehyde dehydrogenase family. (521 aa)
	DgriGH13227	GH13227; Belongs to the aldehyde dehydrogenase family. (518 aa)
	DgriGH16400	GH16400. (406 aa)
	DgriGH16630	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (354 aa)
	DgriGH15455	GH15455. (336 aa)
	DgriGH22640	GH22640; Belongs to the enoyl-CoA hydratase/isomerase family. (298 aa)
	DgriGH17897	GH17897; Belongs to the thiolase-like superfamily. Thiolase family. (409 aa)
	DgriGH14119	GH14119. (700 aa)
	DgriGH22516	GH22516. (424 aa)

Your Current Organism:

Drosophila grimshawi

NCBI taxonomy Id: 7222
Other names: D. grimshawi, Idiomyia grimshawi

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DgriGH11058	DgriGH11066	B4JCF5	B4JCH4	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH11066.	0.434
DgriGH11058	DgriGH11301	B4JCF5	B4JE38	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH11301; Belongs to the thiolase-like superfamily. Thiolase family.	0.992
DgriGH11058	DgriGH13343	B4JCF5	B4JPT0	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH13343.	0.689
DgriGH11058	DgriGH14119	B4JCF5	B4JXZ5	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH14119.	0.956
DgriGH11058	DgriGH14704	B4JCF5	B4IX89	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH14704.	0.978
DgriGH11058	DgriGH14994	B4JCF5	B4J0K9	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.752
DgriGH11058	DgriGH15449	B4JCF5	B4J2E4	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH15449; Belongs to the thiolase-like superfamily. Thiolase family.	0.977
DgriGH11058	DgriGH15455	B4JCF5	B4JUM4	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH15455.	0.971
DgriGH11058	DgriGH16400	B4JCF5	B4JT09	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH16400.	0.971
DgriGH11058	DgriGH16630	B4JCF5	B4JU41	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.953
DgriGH11058	DgriGH16965	B4JCF5	B4IYD8	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH16965.	0.971
DgriGH11058	DgriGH17897	B4JCF5	B4JX76	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH17897; Belongs to the thiolase-like superfamily. Thiolase family.	0.975
DgriGH11058	DgriGH19800	B4JCF5	B4JA17	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.469
DgriGH11058	DgriGH19963	B4JCF5	B4J8F1	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.593
DgriGH11058	DgriGH20195	B4JCF5	B4J635	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH20195; Belongs to the thiolase-like superfamily. Thiolase family.	0.999
DgriGH11058	DgriGH20865	B4JCF5	B4J590	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH20865; Belongs to the enoyl-CoA hydratase/isomerase family.	0.963
DgriGH11058	DgriGH21754	B4JCF5	B4J6K3	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH21754.	0.966
DgriGH11058	DgriGH22516	B4JCF5	B4K041	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH22516.	0.958
DgriGH11058	DgriGH22640	B4JCF5	B4JVM4	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH22640; Belongs to the enoyl-CoA hydratase/isomerase family.	0.411
DgriGH11058	DgriGH24264	B4JCF5	B4JMV1	GH11058; Belongs to the enoyl-CoA hydratase/isomerase family.	GH24264.	0.429