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DgriGH16316 DgriGH16316 DgriGH15789 DgriGH15789 DgriGH15548 DgriGH15548 DgriGH15937 DgriGH15937 DgriGH16613 DgriGH16613 DgriGH16006 DgriGH16006 DgriGH16652 DgriGH16652 DgriGH16653 DgriGH16653 DgriGH16098 DgriGH16098 DgriGH14789 DgriGH14789 DgriGH19727 DgriGH19727 DgriGH20987 DgriGH20987 DgriGH21038 DgriGH21038 DgriGH21072 DgriGH21072 DgriGH20203 DgriGH20203 DgriGH20767 DgriGH20767 DgriGH21209 DgriGH21209 DgriGH21806 DgriGH21806 DgriGH21865 DgriGH21865 DgriGH20609 DgriGH20609 DgriGH19969 DgriGH19969 DgriGH21923 DgriGH21923 DgriGH21411 DgriGH21411 DgriGH19848 DgriGH19848 DgriGH22041 DgriGH22041 DgriGH11385 DgriGH11385 DgriGH11386 DgriGH11386 DgriGH10350 DgriGH10350 DgriGH10920 DgriGH10920 DgriGH11027 DgriGH11027 DgriGH11637 DgriGH11637 DgriGH11165 DgriGH11165 DgriGH10404 DgriGH10404 DgriGH11370 DgriGH11370 DgriGH10362 DgriGH10362 DgriGH19142 DgriGH19142 DgriGH19224 DgriGH19224 DgriGH19225 DgriGH19225 DgriGH19398 DgriGH19398 DgriGH19400 DgriGH19400 DgriGH18893 DgriGH18893 DgriGH19517 DgriGH19517 DgriGH19519 DgriGH19519 DgriGH19550 DgriGH19550 DgriGH19579 DgriGH19579 DgriGH19001 DgriGH19001 DgriGH18481 DgriGH18481 DgriGH12373 DgriGH12373 DgriGH12353 DgriGH12353 DgriGH12509 DgriGH12509 DgriGH12086 DgriGH12086 DgriGH12748 DgriGH12748 DgriGH24550 DgriGH24550 DgriGH24372 DgriGH24372 DgriGH24161 DgriGH24161 DgriGH13337 DgriGH13337 DgriGH13249 DgriGH13249 DgriGH13233 DgriGH13233 DgriGH13785 DgriGH13785 DgriGH21449 DgriGH21449 DgriGH19274 DgriGH19274 DgriGH17453 DgriGH17453 DgriGH15056 DgriGH15056 DgriGH14669 DgriGH14669 DgriGH14021 DgriGH14021 DgriGH22892 DgriGH22892 DgriGH22826 DgriGH22826 DgriGH22755 DgriGH22755 DgriGH17612 DgriGH17612 DgriGH14013 DgriGH14013 DgriGH14000 DgriGH14000 DgriGH22334 DgriGH22334 DgriGH22329 DgriGH22329 DgriGH22384 DgriGH22384 DgriGH23974 DgriGH23974 DgriGH22549 DgriGH22549
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DgriGH16316Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (460 aa)
DgriGH15789GH15789. (4644 aa)
DgriGH15548V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (92 aa)
DgriGH15937V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (85 aa)
DgriGH16613GH16613. (192 aa)
DgriGH16006GH16006. (192 aa)
DgriGH16652V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (161 aa)
DgriGH16653V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (159 aa)
DgriGH16098GH16098. (285 aa)
DgriGH14789V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (89 aa)
DgriGH19727V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (869 aa)
DgriGH20987Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
DgriGH21038GH21038; Belongs to the peptidase C1 family. (349 aa)
DgriGH21072GH21072. (169 aa)
DgriGH20203Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
DgriGH20767GH20767; Belongs to the peptidase C1 family. (329 aa)
DgriGH21209Phosphatidylinositol 3-kinase catalytic subunit type 3. (945 aa)
DgriGH21806Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (99 aa)
DgriGH21865GH21865. (382 aa)
DgriGH20609GH20609; Belongs to the CD36 family. (460 aa)
DgriGH19969GH19969. (246 aa)
DgriGH21923GH21923. (792 aa)
DgriGH21411GH21411; Belongs to the peptidase C1 family. (391 aa)
DgriGH19848GH19848. (1835 aa)
DgriGH22041GH22041; Belongs to the CD36 family. (507 aa)
DgriGH11385GH11385. (614 aa)
DgriGH11386GH11386. (748 aa)
DgriGH10350GH10350. (614 aa)
DgriGH10920V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (173 aa)
DgriGH11027GH11027. (1060 aa)
DgriGH11637GH11637; Belongs to the CD36 family. (504 aa)
DgriGH11165Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (738 aa)
DgriGH10404Integrin beta. (778 aa)
DgriGH11370V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (816 aa)
DgriGH10362GH10362. (546 aa)
DgriGH19142Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
DgriGH19224V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (837 aa)
DgriGH19225V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (848 aa)
DgriGH19398GH19398. (185 aa)
DgriGH19400GH19400. (398 aa)
DgriGH18893Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (490 aa)
DgriGH19517GH19517; Belongs to the V-ATPase proteolipid subunit family. (212 aa)
DgriGH19519GH19519; Belongs to the V-ATPase proteolipid subunit family. (207 aa)
DgriGH19550GH19550. (88 aa)
DgriGH19579Calreticulin. (403 aa)
DgriGH19001Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
DgriGH18481GH18481. (207 aa)
DgriGH12373Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
DgriGH12353GH12353; Belongs to the synaptobrevin family. (211 aa)
DgriGH12509Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (504 aa)
DgriGH12086GH12086. (661 aa)
DgriGH12748GH12748. (250 aa)
DgriGH24550GH24550. (146 aa)
DgriGH24372GH24372. (376 aa)
DgriGH24161Integrin beta; Belongs to the integrin beta chain family. (895 aa)
DgriGH13337Nitric oxide synthase; Produces nitric oxide (NO). (1359 aa)
DgriGH13249GH13249. (476 aa)
DgriGH13233GH13233. (325 aa)
DgriGH13785GH13785. (216 aa)
DgriGH21449V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
DgriGH19274GH19274. (195 aa)
DgriGH17453V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (682 aa)
DgriGH15056Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
DgriGH14669GH14669. (226 aa)
DgriGH14021Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (512 aa)
DgriGH22892V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (161 aa)
DgriGH22826GH22826; Belongs to the peptidase C1 family. (340 aa)
DgriGH22755GH22755. (340 aa)
DgriGH17612V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (352 aa)
DgriGH14013GH14013. (113 aa)
DgriGH14000GH14000. (598 aa)
DgriGH22334Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (455 aa)
DgriGH22329V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (124 aa)
DgriGH22384V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
DgriGH23974GH23974; Belongs to the peptidase C1 family. (337 aa)
DgriGH22549GH22549; Belongs to the CD36 family. (279 aa)
Your Current Organism:
Drosophila grimshawi
NCBI taxonomy Id: 7222
Other names: D. grimshawi, Idiomyia grimshawi
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