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folD folD fba fba prs prs ALA35593.1 ALA35593.1 tkt tkt ALA35656.1 ALA35656.1 pgi pgi ALA35764.1 ALA35764.1 ALA35814.1 ALA35814.1 pyk pyk ALA35819.1 ALA35819.1 lpdA lpdA pdhB pdhB pdhA pdhA pta pta pgk pgk gap gap ALA35986.1 ALA35986.1 ulaD ulaD ALA35988.1 ALA35988.1 ALA35989.1 ALA35989.1 ALA35990.1 ALA35990.1 araD araD ackA ackA ALA36045.1 ALA36045.1 glyA glyA rpiB rpiB eno eno gpmI gpmI tpiA tpiA ldh ldh
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (269 aa)
fbaFructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (328 aa)
ALA35593.1Fructose permease IIC protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (694 aa)
tktTransketolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. (648 aa)
ALA35656.1PAP phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (430 aa)
ALA35764.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
ALA35814.16-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (328 aa)
pykPyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (508 aa)
ALA35819.1Carbamate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbamate kinase family. (309 aa)
lpdADihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
pdhB2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
pdhAPyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (358 aa)
ptaPhosphotransacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (409 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
ALA35986.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
ulaDCatalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
ALA35988.1PTS sugar transporter subunit IIAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
ALA35989.1PTS ascorbate transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
ALA35990.1PTS ascorbate transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (660 aa)
araDCatalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (390 aa)
ALA36045.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (406 aa)
rpiBRibose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (456 aa)
gpmIPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (508 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (244 aa)
ldhLactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (312 aa)
Your Current Organism:
Mycoplasma pneumoniae FH
NCBI taxonomy Id: 722438
Other names: M. pneumoniae FH, Mycoplasma pneumoniae ATCC 15531, Mycoplasma pneumoniae NCTC 10119, Mycoplasma pneumoniae str. FH, Mycoplasma pneumoniae strain FH
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