(15 nodes) Mixed, incl. Sweet taste receptor activity, and Detection of chemical stimulus involved in sensory perception of bitter taste network (Drosophila melanogaster)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	Ir7a	Ionotropic receptor 7a; Ligand-gated ion channel activity. It is involved in the biological process described with: detection of chemical stimulus involved in sensory perception of bitter taste; sensory perception of taste; detection of chemical stimulus. (614 aa)
	Gr58c	Putative gustatory receptor 58c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr10a subfamily. (412 aa)
	Gr59d	Putative gustatory receptor 59d; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (390 aa)
	CG9876	FI01017p; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. (275 aa)
	CG12849	Uncharacterized protein. (172 aa)
	CG8945	Peptidase_M14 domain-containing protein; Zinc ion binding; metallocarboxypeptidase activity. It is involved in the biological process described with: proteolysis. (1430 aa)
	Ir67c	Ionotropic receptor 67c; Ligand-gated ion channel activity. It is involved in the biological process described with: detection of chemical stimulus. (573 aa)
	Gr36c	Putative gustatory receptor 36c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (390 aa)
	CG10864	Uncharacterized protein; Potassium ion leak channel activity; potassium channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (389 aa)
	Gr93d	Gustatory receptor; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. (381 aa)
	CG13634	Uncharacterized protein. (462 aa)
	Gr98b	Putative gustatory receptor 98b; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily. (403 aa)
	Gr98c	Putative gustatory receptor 98c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily. (408 aa)
	CG10280	Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis. (362 aa)
	Nach	Sodium channel protein Nach; Nach (Nach) encodes a predicted member of the Degenerin/Epithelial Sodium Channel family of proteins. It is mainly expressed in the tracheal system and functions in liquid clearance during tracheal development; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (553 aa)

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CG10280	CG10864	FBpp0301222	FBpp0083069	Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.	Uncharacterized protein; Potassium ion leak channel activity; potassium channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	0.684
CG10280	CG12849	FBpp0301222	FBpp0072283	Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.	Uncharacterized protein.	0.638
CG10280	CG13634	FBpp0301222	FBpp0084117	Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.	Uncharacterized protein.	0.684
CG10280	CG8945	FBpp0301222	FBpp0074185	Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.	Peptidase_M14 domain-containing protein; Zinc ion binding; metallocarboxypeptidase activity. It is involved in the biological process described with: proteolysis.	0.601
CG10280	CG9876	FBpp0301222	FBpp0071889	Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.	FI01017p; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated.	0.839
CG10280	Gr36c	FBpp0301222	FBpp0080517	Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.	Putative gustatory receptor 36c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.	0.690
CG10280	Gr58c	FBpp0301222	FBpp0071643	Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.	Putative gustatory receptor 58c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr10a subfamily.	0.641
CG10280	Gr59d	FBpp0301222	FBpp0071886	Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.	Putative gustatory receptor 59d; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.	0.473
CG10280	Gr98b	FBpp0301222	FBpp0084556	Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.	Putative gustatory receptor 98b; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily.	0.412
CG10280	Gr98c	FBpp0301222	FBpp0084557	Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.	Putative gustatory receptor 98c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily.	0.692
CG10280	Ir67c	FBpp0301222	FBpp0076022	Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.	Ionotropic receptor 67c; Ligand-gated ion channel activity. It is involved in the biological process described with: detection of chemical stimulus.	0.690
CG10280	Ir7a	FBpp0301222	FBpp0071032	Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.	Ionotropic receptor 7a; Ligand-gated ion channel activity. It is involved in the biological process described with: detection of chemical stimulus involved in sensory perception of bitter taste; sensory perception of taste; detection of chemical stimulus.	0.638
CG10280	Nach	FBpp0301222	FBpp0401613	Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.	Sodium channel protein Nach; Nach (Nach) encodes a predicted member of the Degenerin/Epithelial Sodium Channel family of proteins. It is mainly expressed in the tracheal system and functions in liquid clearance during tracheal development; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.803
CG10864	CG10280	FBpp0083069	FBpp0301222	Uncharacterized protein; Potassium ion leak channel activity; potassium channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.	0.684
CG10864	CG12849	FBpp0083069	FBpp0072283	Uncharacterized protein; Potassium ion leak channel activity; potassium channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	Uncharacterized protein.	0.700
CG10864	CG13634	FBpp0083069	FBpp0084117	Uncharacterized protein; Potassium ion leak channel activity; potassium channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	Uncharacterized protein.	0.811
CG10864	CG8945	FBpp0083069	FBpp0074185	Uncharacterized protein; Potassium ion leak channel activity; potassium channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	Peptidase_M14 domain-containing protein; Zinc ion binding; metallocarboxypeptidase activity. It is involved in the biological process described with: proteolysis.	0.666
CG10864	CG9876	FBpp0083069	FBpp0071889	Uncharacterized protein; Potassium ion leak channel activity; potassium channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	FI01017p; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated.	0.744
CG10864	Gr36c	FBpp0083069	FBpp0080517	Uncharacterized protein; Potassium ion leak channel activity; potassium channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	Putative gustatory receptor 36c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.	0.803
CG10864	Gr58c	FBpp0083069	FBpp0071643	Uncharacterized protein; Potassium ion leak channel activity; potassium channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	Putative gustatory receptor 58c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr10a subfamily.	0.690