STRINGSTRING
Alg2 Alg2 Alg14 Alg14 wol wol Alg7 Alg7 Dpm1 Dpm1 Alg1 Alg1 Alg13 Alg13 CG8311 CG8311 Dpm3 Dpm3 Dpm2 Dpm2 Alg11 Alg11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Alg2ALG2, alpha-1,3/1,6-mannosyltransferase; Alpha-1,3-mannosyltransferase activity; GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation in endoplasmic reticulum; oligosaccharide-lipid intermediate biosynthetic process. (424 aa)
Alg14ALG14, UDP-N-acetylglucosaminyltransferase subunit; N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity. It is involved in the biological process described with: dolichol-linked oligosaccharide biosynthetic process. (191 aa)
wolDolichyl-phosphate beta-glucosyltransferase; Required for normal production of N-glycosylated proteins in the endoplasmic reticulum (ER). Required for embryonic segmentation, dorsal-ventral patterning and gastrulation. Required for chitin orientation and shaping of the apical and lateral plasma membranes of epidermal cells during cuticle differentiation. Also required for correctly shaping apical membrane topology of the epithelia of other organs such as the midgut and the hindgut. (326 aa)
Alg7GH19029p; phospho-N-acetylmuramoyl-pentapeptide-transferase activity; UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity. It is involved in the biological process described with: protein N-linked glycosylation; dolichyl diphosphate biosynthetic process. (409 aa)
Dpm1Probable dolichol-phosphate mannosyltransferase; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; Belongs to the glycosyltransferase 2 family. (241 aa)
Alg1ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase; Mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation. (446 aa)
Alg13Glyco_tran_28_C domain-containing protein; N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity. It is involved in the biological process described with: dolichol-linked oligosaccharide biosynthetic process. (171 aa)
CG8311Uncharacterized protein; Dolichol kinase activity. It is involved in the biological process described with: dolichyl monophosphate biosynthetic process. (503 aa)
Dpm3Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family. (94 aa)
Dpm2Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (81 aa)
Alg11ALG11, alpha-1,2-mannosyltransferase, isoform A; GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity. It is involved in the biological process described with: protein N-linked glycosylation; oligosaccharide-lipid intermediate biosynthetic process. (475 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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