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Cyp4g1 Cyp4g1 FarO FarO spidey spidey Sc2 Sc2 Baldspot Baldspot Fad2 Fad2 Elo68alpha Elo68alpha Hacd1 Hacd1 Hacd2 Hacd2 CG17928 CG17928 CG7910 CG7910 ELOVL ELOVL eloF eloF CG9458 CG9458 CG9459 CG9459 CG16904 CG16904 CG17562 CG17562 CG17560 CG17560 bond bond CG33110 CG33110 sit sit CG5326 CG5326 CG6660 CG6660 CG31141 CG31141 CG9743 CG9743 CG15531 CG15531 CG17821 CG17821 CG18609 CG18609 CG30008 CG30008 Elo68beta Elo68beta Cyt-b5-r Cyt-b5-r Sgp Sgp CG4020 CG4020 CG31523 CG31523 CG31522 CG31522 CG10097 CG10097
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Cyp4g1Cytochrome P450-4g1 (Cyp4g1) encodes the terminal oxidative decarbonylase in cuticular hydrocarbon biosynthesis within oenocytes. (556 aa)
FarOFatty acyl-CoA reductase in oenocytes (FarO) encodes a long-chain-fatty-acyl-CoA reductase involved in the regulation of cell growth and lipid storage. (504 aa)
spideyRH59310p; Spidey (spidey) encodes a member of the short chain dehydrogenase/reductase family. It regulates oenocyte growth and maturation, as well as the metabolism of ecdysteroids and cuticular hydrocarbons; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (321 aa)
Sc2Sc2; Oxidoreductase activity; oxidoreductase activity, acting on the CH-CH group of donors. It is involved in the biological process described with: very long-chain fatty acid biosynthetic process. (302 aa)
BaldspotElongation of very long chain fatty acids protein; Baldspot (Baldspot) encodes a protein involved in spermatogenesis. (316 aa)
Fad2Fad2 (Fad2) encodes a transmembrane fatty acid desaturase that utilizes mono-unsaturated long-chain fatty acids (LCFAs) to synthesize di-unsaturated LCFAs. It is involved in the synthesis of the female pheromones. (355 aa)
Elo68alphaElongation of very long chain fatty acids protein; Elongase 68alpha (Elo68alpha) encodes a transmembrane fatty acid elongase, elongating Delta9 unsaturated LCFAs (C14 and C16) to Delta11 LCFAs (C16 and C18), that is involved in the synthesis of the male pheromone cis-vaccenyl acetate. (262 aa)
Hacd1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (245 aa)
Hacd2Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (371 aa)
CG17928IP12339p; Oxidoreductase activity. It is involved in the biological process described with: lipid metabolic process. (441 aa)
CG7910AT07710p; Anandamide amidohydrolase activity; acylglycerol lipase activity. (530 aa)
ELOVLElongation of very long chain fatty acids protein; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. (329 aa)
eloFElongation of very long chain fatty acids protein F; Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids, to yield products up to 30 carbons in length. May also elongate diunsaturated fatty acids. Important for courtship behavior where it probably has a role in female pheromone biosynthesis. (257 aa)
CG9458Elongation of very long chain fatty acids protein; Fatty acid elongase activity. (264 aa)
CG9459Elongation of very long chain fatty acids protein; Fatty acid elongase activity. (265 aa)
CG16904Elongation of very long chain fatty acids protein; Fatty acid elongase activity. (262 aa)
CG17562Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (499 aa)
CG17560Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (499 aa)
bondJames bond (bond) encodes a member of the Elov1 family of enzymes that function as very long chain fatty acid elongases. It contributes to sperm generation and the production of the male sex pheromone CH503 in the ejaculatory bulb. (322 aa)
CG33110Elongation of very long chain fatty acids protein; Fatty acid elongase activity. (337 aa)
sitElongation of very long chain fatty acids protein; Fatty acid elongase activity. (295 aa)
CG5326Elongation of very long chain fatty acids protein; Fatty acid elongase activity. (277 aa)
CG6660Elongation of very long chain fatty acids protein; Fatty acid elongase activity. It is involved in the biological process described with: sphingolipid biosynthetic process; very long-chain fatty acid biosynthetic process; fatty acid elongation, saturated fatty acid; fatty acid elongation, polyunsaturated fatty acid; fatty acid elongation, monounsaturated fatty acid. (272 aa)
CG31141Elongation of very long chain fatty acids protein; Fatty acid elongase activity. (253 aa)
CG9743RH14937p; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family. (420 aa)
CG15531FA_desaturase domain-containing protein; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family. (334 aa)
CG17821Elongation of very long chain fatty acids protein; Fatty acid elongase activity. (262 aa)
CG18609Elongation of very long chain fatty acids protein; Fatty acid elongase activity. (263 aa)
CG30008Elongation of very long chain fatty acids protein; Fatty acid elongase activity. (266 aa)
Elo68betaElongation of very long chain fatty acids protein; Fatty acid elongase activity. (269 aa)
Cyt-b5-rCytochrome b5-related protein; May play a role in muscle cell metabolism. (436 aa)
SgpFatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (523 aa)
CG4020Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (494 aa)
CG31523Elongation of very long chain fatty acids protein; Fatty acid elongase activity. (354 aa)
CG31522Elongation of very long chain fatty acids protein; Fatty acid elongase activity. (392 aa)
CG10097Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (501 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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