(6 nodes) Excretion, and POT family network (Drosophila melanogaster)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Your Input:
	Oatp58Dc	Solute carrier organic anion transporter family member; Organic anion transporting polypeptide 58Dc (Oatp58Dc) encodes a membrane transporter implicated in renal elimination of organic compounds including ouabain and methotrexate. In the perineural glia of the blood brain barrier, the product of Oatp58Dc protects the brain from potentially toxic organic anions in the hemolymph. (789 aa)
	CG30344	GH23453p; Transporter activity. It is involved in the biological process described with: response to toxic substance; renal tubular secretion; transmembrane transport. (507 aa)
	CG8046	Uncharacterized protein, isoform A; Peptidoglycan transmembrane transporter activity. It is involved in the biological process described with: positive regulation of antimicrobial humoral response; peptidoglycan transport; transmembrane transport; positive regulation of peptidoglycan recognition protein signaling pathway. (519 aa)
	MRP	Multidrug-Resistance like protein 1, isoform A; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase-coupled inorganic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; anion transmembrane transport. (1549 aa)
	CG9444	Uncharacterized protein, isoform A; Peptide transmembrane transporter activity; oligopeptide transmembrane transporter activity; dipeptide transmembrane transporter activity; peptide:proton symporter activity. It is involved in the biological process described with: oligopeptide transport; transmembrane transport. (557 aa)
	Oatp58Db	Solute carrier organic anion transporter family member; Active transmembrane transporter activity; sodium-independent organic anion transmembrane transporter activity; transmembrane transporter activity. It is involved in the biological process described with: sodium-independent organic anion transport; organic substance transport; transmembrane transport; excretion. (680 aa)

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CG30344	CG9444	FBpp0087664	FBpp0305396	GH23453p; Transporter activity. It is involved in the biological process described with: response to toxic substance; renal tubular secretion; transmembrane transport.	Uncharacterized protein, isoform A; Peptide transmembrane transporter activity; oligopeptide transmembrane transporter activity; dipeptide transmembrane transporter activity; peptide:proton symporter activity. It is involved in the biological process described with: oligopeptide transport; transmembrane transport.	0.432
CG30344	MRP	FBpp0087664	FBpp0089070	GH23453p; Transporter activity. It is involved in the biological process described with: response to toxic substance; renal tubular secretion; transmembrane transport.	Multidrug-Resistance like protein 1, isoform A; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase-coupled inorganic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; anion transmembrane transport.	0.839
CG30344	Oatp58Dc	FBpp0087664	FBpp0071690	GH23453p; Transporter activity. It is involved in the biological process described with: response to toxic substance; renal tubular secretion; transmembrane transport.	Solute carrier organic anion transporter family member; Organic anion transporting polypeptide 58Dc (Oatp58Dc) encodes a membrane transporter implicated in renal elimination of organic compounds including ouabain and methotrexate. In the perineural glia of the blood brain barrier, the product of Oatp58Dc protects the brain from potentially toxic organic anions in the hemolymph.	0.913
CG8046	CG9444	FBpp0087701	FBpp0305396	Uncharacterized protein, isoform A; Peptidoglycan transmembrane transporter activity. It is involved in the biological process described with: positive regulation of antimicrobial humoral response; peptidoglycan transport; transmembrane transport; positive regulation of peptidoglycan recognition protein signaling pathway.	Uncharacterized protein, isoform A; Peptide transmembrane transporter activity; oligopeptide transmembrane transporter activity; dipeptide transmembrane transporter activity; peptide:proton symporter activity. It is involved in the biological process described with: oligopeptide transport; transmembrane transport.	0.827
CG8046	Oatp58Db	FBpp0087701	FBpp0312420	Uncharacterized protein, isoform A; Peptidoglycan transmembrane transporter activity. It is involved in the biological process described with: positive regulation of antimicrobial humoral response; peptidoglycan transport; transmembrane transport; positive regulation of peptidoglycan recognition protein signaling pathway.	Solute carrier organic anion transporter family member; Active transmembrane transporter activity; sodium-independent organic anion transmembrane transporter activity; transmembrane transporter activity. It is involved in the biological process described with: sodium-independent organic anion transport; organic substance transport; transmembrane transport; excretion.	0.603
CG8046	Oatp58Dc	FBpp0087701	FBpp0071690	Uncharacterized protein, isoform A; Peptidoglycan transmembrane transporter activity. It is involved in the biological process described with: positive regulation of antimicrobial humoral response; peptidoglycan transport; transmembrane transport; positive regulation of peptidoglycan recognition protein signaling pathway.	Solute carrier organic anion transporter family member; Organic anion transporting polypeptide 58Dc (Oatp58Dc) encodes a membrane transporter implicated in renal elimination of organic compounds including ouabain and methotrexate. In the perineural glia of the blood brain barrier, the product of Oatp58Dc protects the brain from potentially toxic organic anions in the hemolymph.	0.491
CG9444	CG30344	FBpp0305396	FBpp0087664	Uncharacterized protein, isoform A; Peptide transmembrane transporter activity; oligopeptide transmembrane transporter activity; dipeptide transmembrane transporter activity; peptide:proton symporter activity. It is involved in the biological process described with: oligopeptide transport; transmembrane transport.	GH23453p; Transporter activity. It is involved in the biological process described with: response to toxic substance; renal tubular secretion; transmembrane transport.	0.432
CG9444	CG8046	FBpp0305396	FBpp0087701	Uncharacterized protein, isoform A; Peptide transmembrane transporter activity; oligopeptide transmembrane transporter activity; dipeptide transmembrane transporter activity; peptide:proton symporter activity. It is involved in the biological process described with: oligopeptide transport; transmembrane transport.	Uncharacterized protein, isoform A; Peptidoglycan transmembrane transporter activity. It is involved in the biological process described with: positive regulation of antimicrobial humoral response; peptidoglycan transport; transmembrane transport; positive regulation of peptidoglycan recognition protein signaling pathway.	0.827
MRP	CG30344	FBpp0089070	FBpp0087664	Multidrug-Resistance like protein 1, isoform A; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase-coupled inorganic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; anion transmembrane transport.	GH23453p; Transporter activity. It is involved in the biological process described with: response to toxic substance; renal tubular secretion; transmembrane transport.	0.839
MRP	Oatp58Dc	FBpp0089070	FBpp0071690	Multidrug-Resistance like protein 1, isoform A; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase-coupled inorganic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; anion transmembrane transport.	Solute carrier organic anion transporter family member; Organic anion transporting polypeptide 58Dc (Oatp58Dc) encodes a membrane transporter implicated in renal elimination of organic compounds including ouabain and methotrexate. In the perineural glia of the blood brain barrier, the product of Oatp58Dc protects the brain from potentially toxic organic anions in the hemolymph.	0.670
Oatp58Db	CG8046	FBpp0312420	FBpp0087701	Solute carrier organic anion transporter family member; Active transmembrane transporter activity; sodium-independent organic anion transmembrane transporter activity; transmembrane transporter activity. It is involved in the biological process described with: sodium-independent organic anion transport; organic substance transport; transmembrane transport; excretion.	Uncharacterized protein, isoform A; Peptidoglycan transmembrane transporter activity. It is involved in the biological process described with: positive regulation of antimicrobial humoral response; peptidoglycan transport; transmembrane transport; positive regulation of peptidoglycan recognition protein signaling pathway.	0.603
Oatp58Dc	CG30344	FBpp0071690	FBpp0087664	Solute carrier organic anion transporter family member; Organic anion transporting polypeptide 58Dc (Oatp58Dc) encodes a membrane transporter implicated in renal elimination of organic compounds including ouabain and methotrexate. In the perineural glia of the blood brain barrier, the product of Oatp58Dc protects the brain from potentially toxic organic anions in the hemolymph.	GH23453p; Transporter activity. It is involved in the biological process described with: response to toxic substance; renal tubular secretion; transmembrane transport.	0.913
Oatp58Dc	CG8046	FBpp0071690	FBpp0087701	Solute carrier organic anion transporter family member; Organic anion transporting polypeptide 58Dc (Oatp58Dc) encodes a membrane transporter implicated in renal elimination of organic compounds including ouabain and methotrexate. In the perineural glia of the blood brain barrier, the product of Oatp58Dc protects the brain from potentially toxic organic anions in the hemolymph.	Uncharacterized protein, isoform A; Peptidoglycan transmembrane transporter activity. It is involved in the biological process described with: positive regulation of antimicrobial humoral response; peptidoglycan transport; transmembrane transport; positive regulation of peptidoglycan recognition protein signaling pathway.	0.491
Oatp58Dc	MRP	FBpp0071690	FBpp0089070	Solute carrier organic anion transporter family member; Organic anion transporting polypeptide 58Dc (Oatp58Dc) encodes a membrane transporter implicated in renal elimination of organic compounds including ouabain and methotrexate. In the perineural glia of the blood brain barrier, the product of Oatp58Dc protects the brain from potentially toxic organic anions in the hemolymph.	Multidrug-Resistance like protein 1, isoform A; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase-coupled inorganic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; anion transmembrane transport.	0.670