(6 nodes) Mixed, incl. NEDD8 ultimate buster 1, and Domain of unknown function DUF4806 network (Drosophila melanogaster)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CG9426	GH03286p; Actin binding. (627 aa)
	GILT3	GILT-like protein 3; Involved in the immune response to bacterial infection. (216 aa)
	CG5111	FI08017p; It is involved in the biological process described with: protein ubiquitination; regulation of ubiquitin-dependent protein catabolic process. (614 aa)
	CG42854	DUF4806 domain-containing protein. (160 aa)
	CG43290	Uncharacterized protein. (122 aa)
	Strn-Mlck	Stretchin-Mlck, isoform U; Stretchin-Mlck (Strn-Mlck) encodes a complex locus producing many large protein isoforms, which likely regulate cytoskeletal dynamics in muscles. A shorter isoform is specifically expressed in indirect flight muscle, localizes to the thick filament and is required to prevent flight muscle hypercontraction. Strn-Mlck mutants cannot fly and show flight muscle atrophy. (8255 aa)

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CG42854	CG43290	FBpp0292989	FBpp0297730	DUF4806 domain-containing protein.	Uncharacterized protein.	0.912
CG42854	CG5111	FBpp0292989	FBpp0084254	DUF4806 domain-containing protein.	FI08017p; It is involved in the biological process described with: protein ubiquitination; regulation of ubiquitin-dependent protein catabolic process.	0.835
CG42854	GILT3	FBpp0292989	FBpp0083826	DUF4806 domain-containing protein.	GILT-like protein 3; Involved in the immune response to bacterial infection.	0.791
CG43290	CG42854	FBpp0297730	FBpp0292989	Uncharacterized protein.	DUF4806 domain-containing protein.	0.912
CG43290	CG5111	FBpp0297730	FBpp0084254	Uncharacterized protein.	FI08017p; It is involved in the biological process described with: protein ubiquitination; regulation of ubiquitin-dependent protein catabolic process.	0.840
CG43290	GILT3	FBpp0297730	FBpp0083826	Uncharacterized protein.	GILT-like protein 3; Involved in the immune response to bacterial infection.	0.791
CG5111	CG42854	FBpp0084254	FBpp0292989	FI08017p; It is involved in the biological process described with: protein ubiquitination; regulation of ubiquitin-dependent protein catabolic process.	DUF4806 domain-containing protein.	0.835
CG5111	CG43290	FBpp0084254	FBpp0297730	FI08017p; It is involved in the biological process described with: protein ubiquitination; regulation of ubiquitin-dependent protein catabolic process.	Uncharacterized protein.	0.840
CG5111	CG9426	FBpp0084254	FBpp0080063	FI08017p; It is involved in the biological process described with: protein ubiquitination; regulation of ubiquitin-dependent protein catabolic process.	GH03286p; Actin binding.	0.994
CG5111	GILT3	FBpp0084254	FBpp0083826	FI08017p; It is involved in the biological process described with: protein ubiquitination; regulation of ubiquitin-dependent protein catabolic process.	GILT-like protein 3; Involved in the immune response to bacterial infection.	0.603
CG5111	Strn-Mlck	FBpp0084254	FBpp0307635	FI08017p; It is involved in the biological process described with: protein ubiquitination; regulation of ubiquitin-dependent protein catabolic process.	Stretchin-Mlck, isoform U; Stretchin-Mlck (Strn-Mlck) encodes a complex locus producing many large protein isoforms, which likely regulate cytoskeletal dynamics in muscles. A shorter isoform is specifically expressed in indirect flight muscle, localizes to the thick filament and is required to prevent flight muscle hypercontraction. Strn-Mlck mutants cannot fly and show flight muscle atrophy.	0.994
CG9426	CG5111	FBpp0080063	FBpp0084254	GH03286p; Actin binding.	FI08017p; It is involved in the biological process described with: protein ubiquitination; regulation of ubiquitin-dependent protein catabolic process.	0.994
CG9426	Strn-Mlck	FBpp0080063	FBpp0307635	GH03286p; Actin binding.	Stretchin-Mlck, isoform U; Stretchin-Mlck (Strn-Mlck) encodes a complex locus producing many large protein isoforms, which likely regulate cytoskeletal dynamics in muscles. A shorter isoform is specifically expressed in indirect flight muscle, localizes to the thick filament and is required to prevent flight muscle hypercontraction. Strn-Mlck mutants cannot fly and show flight muscle atrophy.	0.994
GILT3	CG42854	FBpp0083826	FBpp0292989	GILT-like protein 3; Involved in the immune response to bacterial infection.	DUF4806 domain-containing protein.	0.791
GILT3	CG43290	FBpp0083826	FBpp0297730	GILT-like protein 3; Involved in the immune response to bacterial infection.	Uncharacterized protein.	0.791
GILT3	CG5111	FBpp0083826	FBpp0084254	GILT-like protein 3; Involved in the immune response to bacterial infection.	FI08017p; It is involved in the biological process described with: protein ubiquitination; regulation of ubiquitin-dependent protein catabolic process.	0.603
Strn-Mlck	CG5111	FBpp0307635	FBpp0084254	Stretchin-Mlck, isoform U; Stretchin-Mlck (Strn-Mlck) encodes a complex locus producing many large protein isoforms, which likely regulate cytoskeletal dynamics in muscles. A shorter isoform is specifically expressed in indirect flight muscle, localizes to the thick filament and is required to prevent flight muscle hypercontraction. Strn-Mlck mutants cannot fly and show flight muscle atrophy.	FI08017p; It is involved in the biological process described with: protein ubiquitination; regulation of ubiquitin-dependent protein catabolic process.	0.994
Strn-Mlck	CG9426	FBpp0307635	FBpp0080063	Stretchin-Mlck, isoform U; Stretchin-Mlck (Strn-Mlck) encodes a complex locus producing many large protein isoforms, which likely regulate cytoskeletal dynamics in muscles. A shorter isoform is specifically expressed in indirect flight muscle, localizes to the thick filament and is required to prevent flight muscle hypercontraction. Strn-Mlck mutants cannot fly and show flight muscle atrophy.	GH03286p; Actin binding.	0.994