STRINGSTRING
CG32755 CG32755 Lrp4 Lrp4 Hml Hml PVRAP PVRAP lectin-24A lectin-24A crq crq Tep3 Tep3 Tep2 Tep2 gcm2 gcm2 NimC4 NimC4 He He NimB4 NimB4 CG18477 CG18477 Tep1 Tep1 hig hig Pxn Pxn NimB3 NimB3 atilla atilla Hasp Hasp NimB1 NimB1 eater eater Tep4 Tep4 NimB5 NimB5 NimC1 NimC1 Sr-CI Sr-CI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CG32755Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. (315 aa)
Lrp4LDL receptor related protein 4 (Lrp4) encodes a type I transmembrane protein that is enriched in presynaptic terminals and regulates synaptic organization in the olfactory circuit. (2009 aa)
HmlHemolectin, isoform A; Hemolectin (Hml) encodes a large multidomain protein produced by hemocytes and involved in the clotting reaction. (3843 aa)
PVRAPPVR adaptor protein (PVRAP) encodes a protein implicated in VEGF/PDGF signaling. It binds to the product of Pvr and is required for downstream activation of Target of Rapamycin Complex 1. (474 aa)
lectin-24ALectin-24A; Galactose binding; carbohydrate binding. (282 aa)
crqCroquemort (crq) encodes a member of the scavenger receptor class B sub-family. It is expressed in plasmatocyte/macrophages and promotes apoptotic cell clearance. In epidermal cells it plays a role in phagosome maturation in both dendrite pruning and injury. (491 aa)
Tep3Thioester-containing protein 3 (Tep3) encodes a protein involved in the defense response to Gram-positive bacteria. (1469 aa)
Tep2Thioester-containing protein 2 (Tep2) is a member of the Thioester-containing proteins (TEP) family of genes. The product of Tep2 has endopeptidase inhibitor activity and participates in the cellular immune response to certain Gram-negative bacteria. (1420 aa)
gcm2Transcription factor glial cells missing 2; Transcription factor with a minor role promoting glial cell differentiation and a more significant role in hematocyte differentiation. Gcm2, together with gcm, is required for the proliferation of plasmatocyte precursors, the expression of Croquemort protein, and the ability of plasmatocytes to convert into macrophages. (606 aa)
NimC4Nimrod C4 (NimC4) encodes a transmembrane phagocytic receptor that binds phosphatidylserine exposed on apoptotic cells. Its roles include recognition and engulfment of apoptotic cells during development. (377 aa)
HeHemocyte-specific protein HEMESE; It is involved in the biological process described with: encapsulation of foreign target; negative regulation of lamellocyte differentiation; innate immune response. (156 aa)
NimB4Nimrod B4; It is involved in the biological process described with: defense response to bacterium. (448 aa)
CG18477LP15124p; It is involved in the biological process described with: proteolysis. (464 aa)
Tep1Thioester-containing protein 1; Endopeptidase inhibitor activity. It is involved in the biological process described with: innate immune response. (1354 aa)
higHikaru genki (hig) encodes a secretory matrix protein localized to the synaptic clefts of cholinergic synapses. It is required for the accumulation of acetylcholine receptor subunits on the postsynaptic membranes. (958 aa)
PxnPeroxidasin; Plays a role in extracellular matrix consolidation, phagocytosis and defense. (1527 aa)
NimB3GEO11169p1; It is involved in the biological process described with: defense response to bacterium. (122 aa)
atillaAtilla, isoform B. (143 aa)
HaspHig-anchoring scaffold protein, isoform G; Peptidase inhibitor activity. (1677 aa)
NimB1Nimrod B1, isoform B; It is involved in the biological process described with: defense response to bacterium. (403 aa)
eaterEater (eater) encodes a transmembrane receptor of the Nimrod family specifically expressed in hemocytes and required for the phagocytosis of Gram positive bacteria and the attachment of hemocytes to sessile niches. (1074 aa)
Tep4Thioester-containing protein 4 (Tep4) is a member of the Thioester-containing proteins (TEP) family of genes. The product of Tep4 has endopeptidase inhibitor activity and participates in the cellular immune response to certain Gram-negative bacteria. (1498 aa)
NimB5Nimrod B5, isoform A; It is involved in the biological process described with: defense response to bacterium. (315 aa)
NimC1Nimrod C1, isoform B; It is involved in the biological process described with: defense response to bacterium; phagocytosis. (622 aa)
Sr-CIScavenger receptor class C, type I, isoform A; Scavenger receptor activity; polysaccharide binding. It is involved in the biological process described with: immune response; defense response to Gram-negative bacterium; endocytosis; response to bacterium; phagocytosis. (629 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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