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RpL22 RpL22 RpL17 RpL17 RpL29 RpL29 RpL23 RpL23 RpL12 RpL12 RpL39 RpL39 RpL19 RpL19 RpL8 RpL8 RpL28 RpL28 RpL37a RpL37a RpS12 RpS12 RpL14 RpL14 RpL13A RpL13A RpL35A RpL35A RpS27A RpS27A RpL34b RpL34b RpS25 RpS25 RpS20 RpS20 RpL34a RpL34a RpL4 RpL4 RpL32 RpL32 RpL6 RpL6 RpS18 RpS18 RpL18A RpL18A RpLP2 RpLP2 RpS23 RpS23 RpS8 RpS8 RpL15 RpL15 RpL37A RpL37A RpL13 RpL13 Rack1 Rack1 RpL21 RpL21 RpL27 RpL27 RpLP1 RpLP1 RpL18 RpL18 RpL10 RpL10 RpLP0 RpLP0 RpL40 RpL40 RpL27A RpL27A RpL3 RpL3 RpS19a RpS19a RpL30 RpL30 RpS9 RpS9 RpL24 RpL24 RpL7A RpL7A RpL7 RpL7 RpL36A RpL36A RpS13 RpS13 RpL26 RpL26
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RpL22Ribosomal protein L22 (RpL22) encodes a member of the eukaryotic ribosomal protein eL22 family. It is ubiquitously expressed, forms part of the large ribosomal subunit and is involved in protein synthesis. (299 aa)
RpL1760S ribosomal protein L17; Structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; Belongs to the universal ribosomal protein uL22 family. (186 aa)
RpL2960S ribosomal protein L29; Chromatin binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; Belongs to the eukaryotic ribosomal protein eL29 family. (76 aa)
RpL2360S ribosomal protein L23; Large ribosomal subunit rRNA binding; structural constituent of ribosome; myosin binding. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uL14 family. (140 aa)
RpL12Ribosomal protein L12 (RpL12) encodes a protein of the large subunit of the ribosome. It regulates transcription of ribosomal proteins and ribosome biogenesis genes as well as interacting with the Enhancer of Trithorax and Polycomb protein encoded by corto. (165 aa)
RpL3960S ribosomal protein L39; Structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; translation; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa)
RpL19Ribosomal protein L19 (RpL19) encodes a ribosomal structural constituent; Belongs to the eukaryotic ribosomal protein eL19 family. (203 aa)
RpL8Ribosomal protein L8 (RpL8) encodes a ribosomal structural constituent. (256 aa)
RpL2860S ribosomal protein L28; Structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; translation; Belongs to the eukaryotic ribosomal protein eL28 family. (144 aa)
RpL37aProbable 60S ribosomal protein L37-A; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (93 aa)
RpS12Ribosomal protein S12 (RpS12) is an essential gene encoding a protein component of the cytoplasmic small ribosomal subunit. (139 aa)
RpL14Ribosomal protein L14 (RpL14) encodes a component of the large subunit of cytoplasmic ribosomes, which translate mRNAs encoded by the nuclear genome. RpL14 is haploinsufficient - heterozygous mutants display the 'Minute' phenotype, characterized by a slower developmental rate and small adult bristles. (166 aa)
RpL13ARibosomal protein L13A (RpL13A) encodes a component of the large ribosomal subunit, and thus involved in mRNA translation. Mutations in genes encoding ribosomal proteins affect fertility, viability and other Drosophila phenotypes, described as Minute; Belongs to the universal ribosomal protein uL13 family. (205 aa)
RpL35ARibosomal protein L35A; Structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; ribosomal large subunit biogenesis. (157 aa)
RpS27AUbiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involve [...] (156 aa)
RpL34bRibosomal protein L34b (RpL34b) encodes a ribosomal structural constituent. (168 aa)
RpS2540S ribosomal protein S25; Structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; Belongs to the eukaryotic ribosomal protein eS25 family. (117 aa)
RpS2040S ribosomal protein S20; RNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; translation. (120 aa)
RpL34aRibosomal protein L34a, isoform A; Structural constituent of ribosome; myosin binding. It is involved in the biological process described with: translation; ribosome biogenesis; cytoplasmic translation. (162 aa)
RpL460S ribosomal protein L4; Structural constituent of ribosome; RNA binding. It is involved in the biological process described with: cytoplasmic translation; translation; Belongs to the universal ribosomal protein uL4 family. (401 aa)
RpL3260S ribosomal protein L32; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation. (147 aa)
RpL6Ribosomal protein L6, isoform B; RNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; ribosomal large subunit assembly. (262 aa)
RpS18Ribosomal protein S18 (RpS18) encodes a ribosomal protein located at the top of the head of the 40S subunit and contacts several helices of the 18S rRNA. (152 aa)
RpL18A60S ribosomal protein L18a; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the eukaryotic ribosomal protein eL20 family. (177 aa)
RpLP260S acidic ribosomal protein P2; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family. (113 aa)
RpS2340S ribosomal protein S23; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation. (143 aa)
RpS8Ribosomal protein S8 (RpS8) encodes a structural constituent of ribosomes that is involved in larval lymph gland hemopoiesis; Belongs to the eukaryotic ribosomal protein eS8 family. (208 aa)
RpL1560S ribosomal protein L15; Structural constituent of ribosome; RNA binding. It is involved in the biological process described with: cytoplasmic translation; Belongs to the eukaryotic ribosomal protein eL15 family. (204 aa)
RpL37A60S ribosomal protein L37a; Structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; translation; Belongs to the eukaryotic ribosomal protein eL43 family. (92 aa)
RpL13Ribosomal protein L13 (RpL13) encodes a ribosomal structural constituent; Belongs to the eukaryotic ribosomal protein eL13 family. (218 aa)
Rack1Guanine nucleotide-binding protein subunit beta-like protein; Involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes (By similarity). (318 aa)
RpL21Ribosomal protein L21, isoform A; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation. (159 aa)
RpL2760S ribosomal protein L27; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the eukaryotic ribosomal protein eL27 family. (135 aa)
RpLP1Ribosomal protein LP1 (RpLP1) encodes a member of the cytoplasmic large ribosomal protein family. (112 aa)
RpL1860S ribosomal protein L18; Structural constituent of ribosome; RNA binding. It is involved in the biological process described with: cytoplasmic translation; translation. (188 aa)
RpL1060S ribosomal protein L10; Structural constituent of ribosome. It is involved in the biological process described with: translation; ribosomal large subunit assembly; cytoplasmic translation. (218 aa)
RpLP060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10; Belongs to the universal ribosomal protein uL10 family. (317 aa)
RpL40Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] (128 aa)
RpL27ARibosomal protein L27A (RpL27A) encodes a ribosomal structural constituent; Belongs to the universal ribosomal protein uL15 family. (149 aa)
RpL360S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes. (416 aa)
RpS19aRibosomal protein S19a (RpS19a) encodes a structural constituent of ribosomes; Belongs to the eukaryotic ribosomal protein eS19 family. (156 aa)
RpL30Ribosomal protein L30, isoform B; RNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; translation. (111 aa)
RpS9Ribosomal protein S9 (RpS9) encodes a structural constituent of ribosomes. (195 aa)
RpL2460S ribosomal protein L24; Structural constituent of ribosome; RNA binding. It is involved in the biological process described with: cytoplasmic translation; assembly of large subunit precursor of preribosome; translation; ribosomal large subunit assembly; Belongs to the eukaryotic ribosomal protein eL24 family. (155 aa)
RpL7ARibosomal protein L7A (RpL7A) encodes a ribosomal structural constituent; Belongs to the eukaryotic ribosomal protein eL8 family. (271 aa)
RpL760S ribosomal protein L7; Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity). (252 aa)
RpL36ARibosomal protein L36A, isoform A; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the eukaryotic ribosomal protein eL42 family. (104 aa)
RpS13Ribosomal protein S13 (RpS13) encodes a structural constituent of ribosomes; Belongs to the universal ribosomal protein uS15 family. (151 aa)
RpL26Ribosomal protein L26 (RpL26) encodes a protein component of large ribosomal subunits. (149 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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