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CG32727 CG32727 ttm2 ttm2 CG6878 CG6878 Tim17b1 Tim17b1 Tim17a2 Tim17a2 CG7382 CG7382 Tim17a1 Tim17a1 CG11779 CG11779 Hsc70-5 Hsc70-5 Roe1 Roe1 Tim23 Tim23 CG1409 CG1409 CG7394 CG7394 Tim17b2 Tim17b2 blp blp ttm50 ttm50
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CG32727GEO10507p1; ATPase activator activity. It is involved in the biological process described with: protein import into mitochondrial matrix. (122 aa)
ttm2Mitochondrial import inner membrane translocase subunit TIM50-B; Tiny tim 2 (ttm2) encodes a mitochondrial inner membrane protein that is involved in mitochondrial protein translocation and maintenance of mitochondrial membrane potential; Belongs to the TIM50 family. (409 aa)
CG6878RH56103p; It is involved in the biological process described with: protein import into mitochondrial matrix; regulation of autophagy of mitochondrion; protein insertion into mitochondrial inner membrane. (79 aa)
Tim17b1Probable mitochondrial import inner membrane translocase subunit Tim17 1; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (179 aa)
Tim17a2Probable mitochondrial import inner membrane translocase subunit Tim17 4; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (224 aa)
CG7382GM05057p; It is involved in the biological process described with: protein import into mitochondrial matrix. (236 aa)
Tim17a1Probable mitochondrial import inner membrane translocase subunit Tim17 3; Tim17a1 (Tim17a1) encodes a subunit of the TIM23 complex, which is a presequence translocase responsible for transporting proteins across the inner mitochondrial membrane. It modulates the gating of the transmembrane channel of TIM23 and plays a role in both matrix translocation as well as lateral membrane sorting. (222 aa)
CG11779Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (459 aa)
Hsc70-5Heat shock 70 kDa protein cognate 5. (686 aa)
Roe1GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity). (213 aa)
Tim23Translocase of inner mitochondrial membrane 23; Protein transmembrane transporter activity. It is involved in the biological process described with: protein import into mitochondrial matrix. (206 aa)
CG1409Uncharacterized protein; It is involved in the biological process described with: protein import into mitochondrial matrix. (150 aa)
CG7394Mitochondrial import inner membrane translocase subunit TIM14; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity). (128 aa)
Tim17b2Translocase inner membrane 17, isoform A; P-P-bond-hydrolysis-driven protein transmembrane transporter activity. It is involved in the biological process described with: protein import into mitochondrial matrix; protein targeting to mitochondrion. (176 aa)
blpMitochondrial import inner membrane translocase subunit Tim16; Black pearl (blp) encodes a conserved mitochondrial inner membrane protein. Its loss decreases cytochrome c oxidase activity and causes ROS production, leading to melanotic lesions ("black pearls") in blp-deficient flies; Belongs to the TIM16/PAM16 family. (141 aa)
ttm50Mitochondrial import inner membrane translocase subunit TIM50-C; Tiny tim 50 (ttm50) encodes a mitochondrial inner membrane protein that is involved in mitochondrial protein translocation and maintenance of mitochondrial membrane potential. It plays active roles in regulating metabolic levels for modulation of growth in development. (428 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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