GEO10396p1; Cullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family.

LD45245p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.

GEO10396p1; Cullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family.

Cullin homolog 1; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larv [...]

GEO10396p1; Cullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family.

Cullin 6; Ubiquitin-protein transferase activity; ubiquitin protein ligase binding; Belongs to the cullin family.

GEO10396p1; Cullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family.

F-box protein 11 (FBXO11) encodes a subunit of a SCF-like E3 ubiquitin ligase involved in gene silencing mediated by both siRNAs and miRNAs.s.

GEO10396p1; Cullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family.

Partner of paired, isoform B; Partner of paired (Ppa) encodes a protein involved in response to oxidative stress.

GEO10396p1; Cullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family.

RING-box protein 1A; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Required for the specific SCF-dependent proteolysis of CI, but not that of ARM, suggesting that it also participates in the selection of substrates inside the SCF complex. During early metamorphosis, part of [...]

GEO10396p1; Cullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family.

S-phase kinase-associated protein 2 (Skp2) encodes the substrate recognizing component of the SCF-Skp2 ubiquitin ligase. It functions with the product of Cks85A to target the product of dap for destruction. It is required for larval growth and to maintain diploidy in imaginal tissues.

GEO10396p1; Cullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family.

F-box/WD repeat-containing protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Probably recognizes and binds to phosphorylated target proteins (By similarity). In the wing and eye, negatively regulates cell growth and proliferation by mediating the degradation of Myc and cyclin E, respectively. Required for endocycles, but not mitosis in follicle cell epithelium.

GEO10396p1; Cullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family.

Supernumerary limbs (slmb) encodes an essential, conserved F-box protein and a component of the SCF (Skp/Cullin/F-box) E3 ubiquitin-ligase, providing substrate specificity to the SCF. It negatively regulates multiple signaling pathways and cellular processes by promoting the proteasome-mediated degradation or cleavage of its targets, including the products of arm and ci (Wg and Hh signaling), SAK, per and Cap-H2.

LD45245p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.

GEO10396p1; Cullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family.

LD45245p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.

Cullin homolog 1; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larv [...]

LD45245p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.

Cullin 6; Ubiquitin-protein transferase activity; ubiquitin protein ligase binding; Belongs to the cullin family.

LD45245p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.

F-box protein 11 (FBXO11) encodes a subunit of a SCF-like E3 ubiquitin ligase involved in gene silencing mediated by both siRNAs and miRNAs.s.

LD45245p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.

Partner of paired, isoform B; Partner of paired (Ppa) encodes a protein involved in response to oxidative stress.

LD45245p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.

RING-box protein 1A; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Required for the specific SCF-dependent proteolysis of CI, but not that of ARM, suggesting that it also participates in the selection of substrates inside the SCF complex. During early metamorphosis, part of [...]

LD45245p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.

S-phase kinase-associated protein 2 (Skp2) encodes the substrate recognizing component of the SCF-Skp2 ubiquitin ligase. It functions with the product of Cks85A to target the product of dap for destruction. It is required for larval growth and to maintain diploidy in imaginal tissues.

LD45245p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.

SKP1-related A (SkpA) encodes a subunit of Skp, Cullin, F-box (SCF)-containing ubiquitin ligase complexes. It regulates centrosome duplication, chromatin condensation, cell cycle progression, cell polarity, dendrite pruning and endoreduplication.

LD45245p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.

Cullin family protein binding. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family.

LD45245p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.

Cullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family.

Cullin homolog 1; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larv [...]

GEO10396p1; Cullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family.