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Ufd1-like Ufd1-like CG11070 CG11070 Npl4 Npl4 TER94 TER94 CG42383 CG42383 CG5776 CG5776 CG4603 CG4603 CG8892 CG8892 Faf2 Faf2 Plap Plap
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ufd1-likeUbiquitin fusion degradation protein 1 homolog; Functions at a post-ubiquitation step in the ubiquitin fusion degradation (UFD) pathway; Belongs to the UFD1 family. (316 aa)
CG11070BcDNA.LD34475; Ubiquitin-ubiquitin ligase activity. It is involved in the biological process described with: ubiquitin-dependent ERAD pathway; protein polyubiquitination. (993 aa)
Npl4Nuclear protein localization protein 4 homolog; May be part of a complex that binds ubiquitinated proteins and that is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. Belongs to the NPL4 family. (652 aa)
TER94Transitional endoplasmic reticulum ATPase TER94; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Involved in the ubiquitin-proteasome system. Important for oskar mRNA localization and/ [...] (826 aa)
CG42383Uncharacterized protein; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; nuclear envelope reassembly; autophagosome assembly; membrane fusion; Golgi organization. (353 aa)
CG5776LD25466p; ATP binding; ATPase activity. (799 aa)
CG4603Ubiquitin thioesterase OTU1; Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. (371 aa)
CG8892UBX domain-containing protein 7. (496 aa)
Faf2Fas-associated factor 2 (Faf2) encodes a putative ubiquitin ligase with a proteosome dependent function. (464 aa)
PlapPhospholipase A2 activator protein, isoform A; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; ubiquitin recycling. (787 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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