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| | Or19b | Putative odorant receptor 19b; Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration. May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability (By similarity); Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or2a subfamily. (387 aa) |
| | Hmt4-20 | Histone-lysine N-methyltransferase Suv4-20; Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. Acts as a dominant suppressor of position-effect variegation; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily. (1300 aa) |
| | trr | Histone-lysine N-methyltransferase trr; Histone methyltransferase that acts as a coactivator for the ecdysone receptor during development. Specifically trimethylates 'Lys- 4' of histone H3, a specific tag for epigenetic transcriptional activation. Recruited by EcR in an ecdysone-dependent manner causing H3 'Lys-4' trimethylation at ecdysone-inducible promoters, leading to activate expression. Plays a central role in the developing compound eye, during the progression of the morphogenetic furrow and in post- furrow differentiation of the retinal epithelium, notably by activating express [...] (2431 aa) |
| | Smyd3 | SET and MYND domain containing, class 3; Histone-lysine N-methyltransferase activity; protein-lysine N-methyltransferase activity. It is involved in the biological process described with: histone lysine methylation. (468 aa) |
| | Hira | Protein HIRA homolog; Required for the periodic repression of histone gene transcription during the cell cycle (By similarity). Required for replication-independent chromatin assembly. Promotes remodeling of sperm chromatin following fertilization via the incorporation of histone H3.3 and histone H4. Belongs to the WD repeat HIR1 family. (1047 aa) |
| | Caf1-180 | Chromatin assembly factor 1, p180 subunit (Caf1-180) encodes a component of the chromatin assembly factor-1, which couples DNA replication to histone deposition. The product of Caf1-180 is involved in nucleosome organization, DNA endoduplication and double-strand DNA break repair. (1183 aa) |
| | Cfp1 | CXXC-type zinc finger protein 1; Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3. Essential for Set1 association with chromatin and trimethylation of histone H3 at 'Lys-4' at transcription puffs. Additionally, is critical for general chromosomal association of Set1. (663 aa) |
| | CG17440 | AT26187p; It is involved in the biological process described with: positive regulation of transcription, DNA-templated. (366 aa) |
| | Lpt | Lost PHDs of trr (Lpt) encodes a core component of COMPASS-like nuclear receptor coactivator complexes. It is involved in histone methylation and dpp/BMP signaling regulation. (1482 aa) |
| | HDAC1 | Histone deacetylase HDAC1; Catalyzes the deacetylation of lysine residues on the N- terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation may constitute a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. For instance, deacetylation of histone H3 may be a prerequisite for the subsequent recruitment of the histone methyltransferase Su(var)3-9 to histones. Involved in position-effect variegation (PEV). In the larval brain, part of a regulatory network including the transcript [...] (521 aa) |
| | SmydA-4 | SET and MYND domain containing, arthropod-specific, member 4, isoform A; Histone deacetylase binding. It is involved in the biological process described with: negative regulation of gene expression. (532 aa) |
| | Pa1 | PTIP associated 1; It is involved in the biological process described with: histone H3-K4 methylation. (122 aa) |
| | Set2 | Probable histone-lysine N-methyltransferase CG1716; Probable histone methyltransferase. Histone methylation gives specific tags for epigenetic transcriptional activation or repression (By similarity). (2362 aa) |
| | Su(var)3-3 | Possible lysine-specific histone demethylase 1; Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for heterochromatic gene silencing. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and tri-methylated 'Lys-4' of histone H3. May also demethylate 'Lys-9' of histone H3, Plays a role in the repression of neuronal genes; Belongs to the flavin monoamine oxidase family. (890 aa) |
| | asf1 | Histone chaperone asf1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Plays a role in the formation of silent heterochromatin. (218 aa) |
| | Chd3 | Chromodomain-helicase-DNA-binding protein 3; Chd3 (Chd3) encodes a nuclear ATP-dependent nucleosome remodeler of the CHD family. It associates with active chromatin and utilizes the energy of ATP hydrolysis to move nucleosomes along DNA. (892 aa) |
| | SmydA-2 | SET and MYND domain containing, arthropod-specific, member 2; Histone deacetylase binding. It is involved in the biological process described with: negative regulation of gene expression. (530 aa) |
| | Ptip | PAX transcription activation domain interacting protein (Ptip) encodes a component of a Histone H3K4 methyltransferase complex that contributes to Trithorax-mediated epigenetic imprinting during development. (2294 aa) |
| | Smyd4-2 | SET and MYND domain containing, class 4, member 2 (Smyd4-2) encodes a histone deacetylase involved in photoreceptor development, eclosion, and gene expression regulation. (663 aa) |
| | CG33268 | Uncharacterized protein. (94 aa) |
| | Plod | Procollagen-lysine,2-oxoglutarate 5-dioxygenase; Procollagen lysyl hydroxylase (Plod) encodes a lysyl dehydrogenase with roles in Collagen IV biosynthesis. It localizes to the endoplasmic reticulum and is required for the secretion Collagen IV from haemocytes and fat body. (721 aa) |
| | SuUR | Protein suppressor of underreplication; Required for underreplication of DNA, which is found in many late replicating euchromatic regions of salivary gland polytene chromosomes. Functions by promoting the localization and retention of Rif1 to active DNA replication forks where Rif1 inhibits replication fork progression. Controls chromatin organization in polytene chromosomes. (962 aa) |
| | Rbbp5 | Retinoblastoma-binding protein 5 homolog; Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 and of the MLL3/4 complex which also methylates histone H3 'Lys-4'. (489 aa) |
| | Hat1 | Histone acetyltransferase 1 (Hat1) encodes a B-type histone acetyltransferase that localizes to both the cytoplasm and the nucleus. It is involved in the escort machinery of newly synthesized histones encoded by His3 and His4 to chromatin and acetylates the product of His4 at lysines 5 and 12. It also forms a complex with centromeric histone encoded by cid and is involved in cid chromatin assembly. (405 aa) |
| | CG31915 | Glycosyltransferase 25 family member; Procollagen galactosyltransferase activity. (612 aa) |
| | Su(var)205 | Heterochromatin protein 1; Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. (206 aa) |
| | Wdr82 | WD repeat domain 82 (Wdr82) encodes a component of the Compass complex, which performs K4 methylation of the histone encoded by His3. (317 aa) |
| | Utx | Utx histone demethylase (Utx) encodes a Jumonji C containing protein that catalyzes the removal of methyl groups from Histone H3 lysine 27. Together with the products of trr and Lpt, it is thought to regulate chromatin structure at transcriptional enhancers. (1136 aa) |
| | Dpy-30L1 | Dpy-30-like 1 (Dpy-30L1) encodes a protein that is part of the COMPASS complex, a histone H3K4 methyltransferase complex thought to be responsible for the bulk of the histone H3K4 di- and trimethylation. The product of Dpy-30L1 binds to, and thereby inhibits, the metal-responsive transcription factor encoded by MTF-1. (134 aa) |
| | Ranbp9 | Ran GTPase binding. It is involved in the biological process described with: protein import into nucleus. (1018 aa) |
| | PR-Set7 | Histone-lysine N-methyltransferase PR-Set7; Histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4. H4 'Lys-20' monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, possibly by contributing to the maintenance of proper higher-order structure of DNA and chromosome condensation during mitosis; Belongs to the class V-like SAM-binding methyltransferase superfa [...] (691 aa) |
| | trx | Histone-lysine N-methyltransferase trithorax; Histone methyltransferase that trimethylates 'Lys-9' of histone H3 (H3K9me3). H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional activation. Functions in segment determination through interaction with genes of bithorax (BX-C) and antennapedia (ANT-C) complexes. Acts as an activator of BX-C. Involved in the very early regulation of homeotic genes expressed only in the posterior region of the embryo. (3726 aa) |
| | His4r | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | CG14282 | IP09474p; It is involved in the biological process described with: histone H3-K4 methylation. (293 aa) |
| | Smyd5 | SET and MYND domain containing, class 5; S-adenosylmethionine-dependent methyltransferase activity. It is involved in the biological process described with: histone lysine methylation. (393 aa) |
| | CG10254 | Uncharacterized protein, isoform A; Ubiquitin-protein transferase activity; ubiquitin conjugating enzyme activity. It is involved in the biological process described with: protein polyubiquitination; ubiquitin-dependent protein catabolic process; protein monoubiquitination. (1398 aa) |
| | CG17784 | Uncharacterized protein. (237 aa) |
| | ash2 | Set1/Ash2 histone methyltransferase complex subunit ASH2; Transcriptional regulator. Regulates a number of genes involved in wing development including activation of net and bs and repression of rho and kni and controls vein-intervein patterning during wing development. Required for correct expression of a number of homeotic genes including Scr in the first leg imaginal disk and Ubx in the third leg imaginal disk and haltere disks. Required for stabilization of the histone-lysine N-methyltransferase trr and for trimethylation of 'Lys-4' of histone H3. Plays a role in maintenance of tra [...] (556 aa) |
| | NSD | Probable histone-lysine N-methyltransferase Mes-4; Probable histone methyltransferase. Histone methylation gives specific tags for epigenetic transcriptional activation or repression (By similarity); Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (1427 aa) |
| | Jasper | LD23804p. (475 aa) |
| | His1:CG31617 | Histone H1; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. (256 aa) |
| | His2A:CG31618 | Histone H2A; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (124 aa) |
| | His3:CG31613 | Histone H3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa) |
| | His4:CG31611 | Histone binding; DNA binding; protein heterodimerization activity. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG17949 | Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (123 aa) |
| | SmydA-5 | SET and MYND domain containing, arthropod-specific, member 5; Histone deacetylase binding. It is involved in the biological process described with: negative regulation of gene expression. (553 aa) |
| | SmydA-6 | SET and MYND domain containing, arthropod-specific, member 6; Histone deacetylase binding. It is involved in the biological process described with: negative regulation of gene expression. (498 aa) |
| | Rif1 | Telomere-associated protein RIF1; Regulates the timing of initiation of DNA replication. Functions in copy number control by promoting the underreplication of DNA, which is found in many late replicating euchromatic regions of salivary gland polytene chromosomes. Promotes underreplication by localizing to active DNA replication forks in a partially SuUR-dependent manner, and inhibiting replication fork progression. Might also work as an adapter to recruit Pp1-87B to multiple sites on the chromosome and may function with Pp1-87B to mediate underreplication. Plays an essential role in em [...] (1416 aa) |
| | Smyd4-4 | SET and MYND domain containing, class 4, member 4; Histone deacetylase binding. It is involved in the biological process described with: compound eye photoreceptor development; negative regulation of gene expression. (573 aa) |
| | Caf1-105 | Chromatin assembly factor 1, p105 subunit (Caf1-105) encodes one of the three subunits of Drosophila chromatin assembly factor 1 (CAF-1). It binds to histones and contributes to heterochromatin formation and maintenance, chromatin assembly, and developmental signal transduction such the Notch signaling pathway. (747 aa) |
| | Smyd4-1 | SET and MYND domain containing, class 4, member 1, isoform B; Histone deacetylase binding. It is involved in the biological process described with: negative regulation of gene expression; compound eye photoreceptor development. (751 aa) |
| | CG10931 | IP10415p; Histone methyltransferase activity (H3-K4 specific). It is involved in the biological process described with: histone H3-K4 methylation; histone H3 acetylation. (345 aa) |
| | His1:CG33801 | Histone H1; Nucleosomal DNA binding; double-stranded DNA binding; chromatin DNA binding. (256 aa) |
| | His3:CG33803 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33804 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His3:CG33806 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33807 | Histone H1; Nucleosomal DNA binding; double-stranded DNA binding; chromatin DNA binding. (256 aa) |
| | His2A:CG33808 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33809 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33810 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His3:CG33812 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33813 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33814 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33815 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33816 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33817 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33818 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33819 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33820 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33821 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33822 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33823 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33824 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33825 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33826 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33827 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33828 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33829 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33830 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33831 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33832 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33833 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33834 | Histone H1; Double-stranded DNA binding; chromatin DNA binding; nucleosomal DNA binding. (256 aa) |
| | His2A:CG33835 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33836 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33837 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33838 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33839 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33840 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33841 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33842 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33843 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33844 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33845 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33846 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33847 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33848 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33849 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33850 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33851 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33852 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33853 | Histone H2A; Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin organization; Belongs to the histone H2A family. (124 aa) |
| | His3:CG33854 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33855 | Histone H1; Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33856 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33857 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33858 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33859 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33860 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33861 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33862 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33863 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33864 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33865 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33866 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His2B:CG33868 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33869 | DNA binding; protein heterodimerization activity; histone binding. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33870 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33871 | Histone binding; DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33872 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33873 | DNA binding; protein heterodimerization activity; histone binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33874 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33875 | Histone binding; protein heterodimerization activity; DNA binding. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33876 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33877 | Histone binding; DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33878 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33879 | Histone binding; protein heterodimerization activity; DNA binding. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33880 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33881 | Protein heterodimerization activity; DNA binding; histone binding. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33882 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33883 | Protein heterodimerization activity; DNA binding; histone binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33884 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33885 | Histone binding; DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33886 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33887 | Histone binding; DNA binding; protein heterodimerization activity. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33888 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33889 | Protein heterodimerization activity; DNA binding; histone binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33890 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33891 | Protein heterodimerization activity; DNA binding; histone binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33892 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33893 | DNA binding; protein heterodimerization activity; histone binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33894 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33895 | Histone binding; protein heterodimerization activity; DNA binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33896 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33897 | DNA binding; protein heterodimerization activity; histone binding. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33898 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33899 | Histone binding; protein heterodimerization activity; DNA binding. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33900 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33901 | His4:CG33901 (His4:CG33901) encodes a histone H4 replacement variant that is part of the nucleosome core. It is the predominant histone H4 in non-dividing cells. Its amino acid sequence is identical to the cell-cycle regulated histone encoded by His4. (103 aa) |
| | His2B:CG33902 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33903 | Histone binding; protein heterodimerization activity; DNA binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33904 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33905 | Histone binding; protein heterodimerization activity; DNA binding. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33906 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33907 | Histone binding; protein heterodimerization activity; DNA binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33908 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33909 | Histone binding; DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33910 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | Df31 | Decondensation factor 31 (Df31) encodes a histone binding protein involved in nucleosome assembly. (183 aa) |
| | Mnn1 | Menin 1 (Mnn1) encodes a protein that regulates the response of several stresses including hypoxia, hyperosmolarity, heat shock, and oxidative stress. It is important during the mitotic G1 DNA damage checkpoint in a process mediated by the product of CHES-1-like. (763 aa) |
| | CG4565 | Uncharacterized protein; Histone methyltransferase activity (H3-K36 specific); zinc ion binding. It is involved in the biological process described with: histone methylation; histone lysine methylation. (269 aa) |
| | Set1 | Histone-lysine N-methyltransferase SETD1; Catalytic component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 and is the main di- and trimethyltransferase throughout development. Set1-dependent trimethylation regulates chromatin changes at active promoters that ensure optimal RNA polymerase II release into productive elongation, thereby contributing to optimal transcription. (1641 aa) |
| | CG42381 | GH02741p1. (76 aa) |
| | CG42379 | GH02741p2. (84 aa) |
| | CG3347 | FI16849p1; It is involved in the biological process described with: positive regulation of transcription, DNA-templated. (538 aa) |
| | CoRest | CoRest, isoform G; CoRest (CoRest) encodes a DNA binding factor that controls transcription in cooperation with other transcriptional regulators. It positively modulates Notch signaling as well as showing co-repressor activity via histone modification regulation. (824 aa) |
| | CG13613 | Uncharacterized protein. (219 aa) |
| | gpp | Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase. Methylates 'Lys-79' of histone H3. Required for Polycomb Group (PcG) and trithorax Group (trxG) maintenance of expression. Also involved in telomeric silencing but do not in centric heterochromatin. Probably participates in pairing sensitivity. (2137 aa) |
| | HDAC11 | Histone deacetylase activity. (343 aa) |
| | CG33060 | Uncharacterized protein; It is involved in the biological process described with: histone H3-K4 methylation. (121 aa) |
| | Chd1 | Chromodomain-helicase-DNA-binding protein 1; ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin remodeling, but also required to maintain a specific chromatin configuration across the genome (By similarity). Involv [...] (1900 aa) |
| | Nap1 | Nucleosome assembly protein 1 (Nap1) encodes a core histone chaperone involved in histone nuclear transfer and chromatin assembly. (370 aa) |
| | CG8223 | Protein NASP homolog; Histone binding. It is involved in the biological process described with: DNA replication-dependent nucleosome assembly; CENP-A containing nucleosome assembly; Belongs to the NASP family. (492 aa) |
| | Su(var)3-9 | Histone-lysine N-methyltransferase Su(var)3-9; Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting Su(var)205/HP1 to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric regions. Involved in heterochromatic gene silencing including the modification of position-effect-variegation. Belongs to the cl [...] (635 aa) |
| | Ncoa6 | Nuclear receptor coactivator 6 (Ncoa6) encodes a subunit of the Trithorax-related (Trr) complex, a COMPASS-like complex that mediates the methylation of histone H3K4. The product of Ncoa6 is required for transcriptional output of the Hippo pathway by directly interacting with the protein encoded by yki and recruiting the Trr complex to Hippo target genes. (2467 aa) |
| | yem | Yemanuclein (yem) is a maternally expressed gene essential in the oocyte for meiosis and in the zygote for male pronucleus chromatin assembly. yem encodes a chaperone of H3.3 histone variant in partnership with the protein encoded by Hira. It also interacts with components of the Cohesin and the synaptonemal complexes. (1101 aa) |
| | HDAC6 | Histone deacetylase 6, isoform G; Histone deacetylase 6 (HDAC6) encodes a cytosolic deacetylase that functions as a key modulator of proteostasis by mediating ubiquitin-proteasomal and lysosomal degradation of native and/or misfolded proteins. (1179 aa) |
| | CG3708 | Uncharacterized protein; Chromatin binding; histone binding. It is involved in the biological process described with: cell differentiation; nucleosome assembly. (362 aa) |
| | CG43799 | Uncharacterized protein. (249 aa) |
| | SmydA-3 | SET and MYND domain containing, arthropod-specific, member 3, isoform D. (507 aa) |
| | G9a | G9a, isoform B; G9a (G9a) encodes a histone-lysine methyltransferase involved in epigenetic regulation. It contributes to multiple processes including gene expression, dendrite morphogenesis, larval locomotory behavior as well as short and long-term memory. (1657 aa) |
| | His3.3A | Histone H3.3A; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes and is specifically enriched in modifications associated with active chromatin. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular mach [...] (136 aa) |
| | Tasp1 | Taspase 1 (Tasp1) encodes a threonine-type endopeptidase involved in spermatogenesis and the defense response to Gram-negative bacteria. (365 aa) |
| | Alh | Alhambra, isoform P; Alhambra (Alh) encodes a zinc finger/leucine zipper nuclear protein. It is required in the nervous system for maintaining eve expression and normal growth. It is also involved in muscle development and male courtship behavior. (1717 aa) |
| | CG10947 | FI04554p; S-adenosylmethionine-dependent methyltransferase activity; calmodulin-lysine N-methyltransferase activity. It is involved in the biological process described with: regulation of translation. (404 aa) |
| | HmgD | High mobility group protein D; Binds preferentially single-stranded DNA and unwinds double- stranded DNA. Prefers sites containing the sequence 5'-ttg-3'. Facilitates DNA bending. Associated with early embryonic chromatin in the absence of histone H1. (112 aa) |
