(5 nodes) Mixed, incl. SAPAP family, and Astral microtubule nucleation network (Drosophila melanogaster)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	CG8173	RE25723p; Protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: protein phosphorylation; mitotic cell cycle. (398 aa)
	asp	Protein abnormal spindle; Required to maintain the structure of the centrosomal microtubule organizing center (MTOC) during mitosis. May have a preferential role in regulating neurogenesis. Required for germ cell mitosis and oocyte differentiation. (1954 aa)
	CG32318	RT07324p; ATP-dependent microtubule motor activity, plus-end-directed; microtubule motor activity; ATP binding; microtubule binding. It is involved in the biological process described with: microtubule-based movement; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (164 aa)
	CG42232	Uncharacterized protein. (3441 aa)
	mars	Mars (mars) encodes a microtubule-associated protein that shuttles between the mitotic spindle and the nucleus. It is required for mitotic spindle attachment to the centrosome; Belongs to the SAPAP family. (921 aa)

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CG32318	CG42232	FBpp0088995	FBpp0288574	RT07324p; ATP-dependent microtubule motor activity, plus-end-directed; microtubule motor activity; ATP binding; microtubule binding. It is involved in the biological process described with: microtubule-based movement; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.789
CG32318	CG8173	FBpp0088995	FBpp0074249	RT07324p; ATP-dependent microtubule motor activity, plus-end-directed; microtubule motor activity; ATP binding; microtubule binding. It is involved in the biological process described with: microtubule-based movement; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	RE25723p; Protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: protein phosphorylation; mitotic cell cycle.	0.831
CG32318	asp	FBpp0088995	FBpp0084071	RT07324p; ATP-dependent microtubule motor activity, plus-end-directed; microtubule motor activity; ATP binding; microtubule binding. It is involved in the biological process described with: microtubule-based movement; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Protein abnormal spindle; Required to maintain the structure of the centrosomal microtubule organizing center (MTOC) during mitosis. May have a preferential role in regulating neurogenesis. Required for germ cell mitosis and oocyte differentiation.	0.904
CG32318	mars	FBpp0088995	FBpp0311207	RT07324p; ATP-dependent microtubule motor activity, plus-end-directed; microtubule motor activity; ATP binding; microtubule binding. It is involved in the biological process described with: microtubule-based movement; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Mars (mars) encodes a microtubule-associated protein that shuttles between the mitotic spindle and the nucleus. It is required for mitotic spindle attachment to the centrosome; Belongs to the SAPAP family.	0.912
CG42232	CG32318	FBpp0288574	FBpp0088995	Uncharacterized protein.	RT07324p; ATP-dependent microtubule motor activity, plus-end-directed; microtubule motor activity; ATP binding; microtubule binding. It is involved in the biological process described with: microtubule-based movement; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.789
CG42232	CG8173	FBpp0288574	FBpp0074249	Uncharacterized protein.	RE25723p; Protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: protein phosphorylation; mitotic cell cycle.	0.710
CG42232	asp	FBpp0288574	FBpp0084071	Uncharacterized protein.	Protein abnormal spindle; Required to maintain the structure of the centrosomal microtubule organizing center (MTOC) during mitosis. May have a preferential role in regulating neurogenesis. Required for germ cell mitosis and oocyte differentiation.	0.914
CG42232	mars	FBpp0288574	FBpp0311207	Uncharacterized protein.	Mars (mars) encodes a microtubule-associated protein that shuttles between the mitotic spindle and the nucleus. It is required for mitotic spindle attachment to the centrosome; Belongs to the SAPAP family.	0.877
CG8173	CG32318	FBpp0074249	FBpp0088995	RE25723p; Protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: protein phosphorylation; mitotic cell cycle.	RT07324p; ATP-dependent microtubule motor activity, plus-end-directed; microtubule motor activity; ATP binding; microtubule binding. It is involved in the biological process described with: microtubule-based movement; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.831
CG8173	CG42232	FBpp0074249	FBpp0288574	RE25723p; Protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: protein phosphorylation; mitotic cell cycle.	Uncharacterized protein.	0.710
CG8173	asp	FBpp0074249	FBpp0084071	RE25723p; Protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: protein phosphorylation; mitotic cell cycle.	Protein abnormal spindle; Required to maintain the structure of the centrosomal microtubule organizing center (MTOC) during mitosis. May have a preferential role in regulating neurogenesis. Required for germ cell mitosis and oocyte differentiation.	0.907
CG8173	mars	FBpp0074249	FBpp0311207	RE25723p; Protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: protein phosphorylation; mitotic cell cycle.	Mars (mars) encodes a microtubule-associated protein that shuttles between the mitotic spindle and the nucleus. It is required for mitotic spindle attachment to the centrosome; Belongs to the SAPAP family.	0.924
asp	CG32318	FBpp0084071	FBpp0088995	Protein abnormal spindle; Required to maintain the structure of the centrosomal microtubule organizing center (MTOC) during mitosis. May have a preferential role in regulating neurogenesis. Required for germ cell mitosis and oocyte differentiation.	RT07324p; ATP-dependent microtubule motor activity, plus-end-directed; microtubule motor activity; ATP binding; microtubule binding. It is involved in the biological process described with: microtubule-based movement; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.904
asp	CG42232	FBpp0084071	FBpp0288574	Protein abnormal spindle; Required to maintain the structure of the centrosomal microtubule organizing center (MTOC) during mitosis. May have a preferential role in regulating neurogenesis. Required for germ cell mitosis and oocyte differentiation.	Uncharacterized protein.	0.914
asp	CG8173	FBpp0084071	FBpp0074249	Protein abnormal spindle; Required to maintain the structure of the centrosomal microtubule organizing center (MTOC) during mitosis. May have a preferential role in regulating neurogenesis. Required for germ cell mitosis and oocyte differentiation.	RE25723p; Protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: protein phosphorylation; mitotic cell cycle.	0.907
asp	mars	FBpp0084071	FBpp0311207	Protein abnormal spindle; Required to maintain the structure of the centrosomal microtubule organizing center (MTOC) during mitosis. May have a preferential role in regulating neurogenesis. Required for germ cell mitosis and oocyte differentiation.	Mars (mars) encodes a microtubule-associated protein that shuttles between the mitotic spindle and the nucleus. It is required for mitotic spindle attachment to the centrosome; Belongs to the SAPAP family.	0.975
mars	CG32318	FBpp0311207	FBpp0088995	Mars (mars) encodes a microtubule-associated protein that shuttles between the mitotic spindle and the nucleus. It is required for mitotic spindle attachment to the centrosome; Belongs to the SAPAP family.	RT07324p; ATP-dependent microtubule motor activity, plus-end-directed; microtubule motor activity; ATP binding; microtubule binding. It is involved in the biological process described with: microtubule-based movement; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.912
mars	CG42232	FBpp0311207	FBpp0288574	Mars (mars) encodes a microtubule-associated protein that shuttles between the mitotic spindle and the nucleus. It is required for mitotic spindle attachment to the centrosome; Belongs to the SAPAP family.	Uncharacterized protein.	0.877
mars	CG8173	FBpp0311207	FBpp0074249	Mars (mars) encodes a microtubule-associated protein that shuttles between the mitotic spindle and the nucleus. It is required for mitotic spindle attachment to the centrosome; Belongs to the SAPAP family.	RE25723p; Protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: protein phosphorylation; mitotic cell cycle.	0.924
mars	asp	FBpp0311207	FBpp0084071	Mars (mars) encodes a microtubule-associated protein that shuttles between the mitotic spindle and the nucleus. It is required for mitotic spindle attachment to the centrosome; Belongs to the SAPAP family.	Protein abnormal spindle; Required to maintain the structure of the centrosomal microtubule organizing center (MTOC) during mitosis. May have a preferential role in regulating neurogenesis. Required for germ cell mitosis and oocyte differentiation.	0.975