STRINGSTRING
CG1999 CG1999 CG3124 CG3124 Ppm1 Ppm1 CG13898 CG13898 CG9129 CG9129 CG2113 CG2113 CG18418 CG18418 CG11106 CG11106 ms(3)76Ca ms(3)76Ca goddard goddard CG13476 CG13476 CG17666 CG17666 CG12362 CG12362 S-Lap4 S-Lap4 CG3222 CG3222 CG3982 CG3982 S-Lap1 S-Lap1 CG17744 CG17744 CG4669 CG4669 CG2955 CG2955 CG3213 CG3213 CG8838 CG8838 CG8813 CG8813 CG31948 CG31948 nis nis CG5565 CG5565 CG4375 CG4375 CG10589 CG10589 Mst77F Mst77F CG33284 CG33284 CG18266 CG18266 Hsp60C Hsp60C CG18662 CG18662 Mst33A Mst33A CG4691 CG4691 ProtB ProtB ProtA ProtA CG5050 CG5050 CG31802 CG31802 CG17344 CG17344 CG15475 CG15475 CG17470 CG17470 Mst84Da Mst84Da Mst84Db Mst84Db Mst84Dc Mst84Dc Mst84Dd Mst84Dd Mst84B Mst84B sowi sowi CG10919 CG10919 CG14718 CG14718 I-t I-t ssp5 ssp5 vrs vrs CG8476 CG8476 CG3199 CG3199 CG14355 CG14355 CG9920 CG9920 CG7886 CG7886 CG14861 CG14861 CG5614 CG5614 CG31244 CG31244 CG3581 CG3581 Dic2 Dic2 Theg Theg tHMG1 tHMG1 Tpl94D Tpl94D CG10252 CG10252 CG33340 CG33340 CG5762 CG5762 CG5024 CG5024 CG3330 CG3330 mil mil Mst98Ca Mst98Ca Mst98Cb Mst98Cb Ppi1 Ppi1 ocn ocn CG2267 CG2267 eIF4H2 eIF4H2 CG31204 CG31204 CG8517 CG8517 CG15124 CG15124 CG15128 CG15128 CG10934 CG10934 S-Lap8 S-Lap8 CG5089 CG5089 CG10734 CG10734 CG12860 CG12860 CG12861 CG12861 S-Lap7 S-Lap7 CG4712 CG4712 CG12902 CG12902 CG30350 CG30350 CG8701 CG8701 CG2127 CG2127 salto salto sut4 sut4 CG18449 CG18449 dj dj CG9133 CG9133 CG34168 CG34168 loopin-1 loopin-1 CG4836 CG4836 CG15109 CG15109 CG12699 CG12699 tHMG2 tHMG2 Prtl99C Prtl99C CG43072 CG43072 CG15219 CG15219 CG17377 CG17377 CG15306 CG15306 CG13243 CG13243 Tektin-A Tektin-A CG13245 CG13245 CG8564 CG8564 CG6380 CG6380 CG4983 CG4983 CG13541 CG13541 CG31988 CG31988 CG14926 CG14926 CG18568 CG18568 CG1394 CG1394 CG6304 CG6304 CG46059 CG46059 CG46298 CG46298
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CG1999FI06480p. (210 aa)
CG3124AT07821p. (283 aa)
Ppm1AT28366p; Cation binding; protein serine/threonine phosphatase activity; magnesium-dependent protein serine/threonine phosphatase activity; phosphoprotein phosphatase activity. It is involved in the biological process described with: protein dephosphorylation. (352 aa)
CG13898GEO12020p1; Calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling. (151 aa)
CG9129FI08042p. (251 aa)
CG2113LP16467p; Actin binding. It is involved in the biological process described with: positive regulation of DNA-binding transcription factor activity; positive regulation of Rho protein signal transduction; positive regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II. (183 aa)
CG18418CG18418 protein; Oxoglutarate:malate antiporter activity. It is involved in the biological process described with: malate transport; mitochondrial transport; alpha-ketoglutarate transport; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
CG11106GEO08757p1. (112 aa)
ms(3)76CaMale sterile (3) 76Ca. (268 aa)
goddardGEO12017p1; Goddard (goddard) is a newly evolved gene that encodes a predicted disordered protein with no homology to other protein families. It is implicated in male reproduction, as males with reduced goddard expression fail to produce sperm. (113 aa)
CG13476GEO12094p1. (149 aa)
CG17666Uncharacterized protein, isoform A. (872 aa)
CG12362RBR-type E3 ubiquitin transferase; Ubiquitin conjugating enzyme binding; ubiquitin protein ligase activity; zinc ion binding; ubiquitin-protein transferase activity. It is involved in the biological process described with: positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ubiquitin-dependent protein catabolic process; protein polyubiquitination. (511 aa)
S-Lap4Sperm-Leucylaminopeptidase 4; Metalloexopeptidase activity; aminopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis. (524 aa)
CG3222Uncharacterized protein. (379 aa)
CG3982Uncharacterized protein. (349 aa)
S-Lap1Sperm-Leucylaminopeptidase 1; Aminopeptidase activity; metalloexopeptidase activity; manganese ion binding. It is involved in the biological process described with: mushroom body development; proteolysis. (555 aa)
CG17744AT01876p. (238 aa)
CG4669FI09606p. (611 aa)
CG2955GH14206p; Microtubule plus-end binding; microtubule binding. It is involved in the biological process described with: spindle assembly; regulation of microtubule polymerization or depolymerization; protein localization to microtubule plus-end; protein localization to microtubule. (565 aa)
CG3213FI13205p. (676 aa)
CG8838Uncharacterized protein. (223 aa)
CG8813GH27752p. (284 aa)
CG31948Uncharacterized protein, isoform B. (372 aa)
nisLP24076p. (659 aa)
CG5565CG5565 protein; Phosphatase activity; magnesium ion binding. (240 aa)
CG4375AT13819p. (169 aa)
CG10589GH01788p. (386 aa)
Mst77FHistone-like protein 18C; Not known. Encoded in the intron of cAMP-dependent protein kinase regulatory chain type I. (215 aa)
CG33284Uncharacterized protein. (115 aa)
CG18266GH11218p. (486 aa)
Hsp60CHeat shock protein 60C (Hsp60C) encodes one of the four Hsp60 family chaperone proteins. It is widely expressed and essential for embryonic viability and tracheal formation. It has essential roles in spermatogenesis and oogenesis, possibly through interaction with F-Actin. (576 aa)
CG18662Protein histidine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation; peptidyl-histidine dephosphorylation. (146 aa)
Mst33AMst33A, isoform A. (359 aa)
CG4691GH20441p. (262 aa)
ProtBProtamine B (ProtB) encodes a protamine protein involved in packaging the paternal genome in sperm. Protamines are small highly basic proteins with numerous cysteines. (144 aa)
ProtAProtamine A (ProtA) encodes a protamine protein involved in packaging the paternal genome in sperm. Protamines are small highly basic proteins with numerous cysteines. (146 aa)
CG5050AT13217p1. (327 aa)
CG31802AT22559p; Calcium ion binding. It is involved in the biological process described with: centriole replication; mitotic cell cycle. (186 aa)
CG17344Uncharacterized protein. (154 aa)
CG15475Uncharacterized protein. (233 aa)
CG17470GH26094p; It is involved in the biological process described with: mesoderm development. (215 aa)
Mst84DaMale-specific sperm protein Mst84Da; It is involved in the biological process described with: sperm axoneme assembly; spermatogenesis. (63 aa)
Mst84DbIt is involved in the biological process described with: spermatogenesis; sperm axoneme assembly. (74 aa)
Mst84DcMale-specific sperm protein Mst84Dc; It is involved in the biological process described with: sperm axoneme assembly; spermatogenesis. (55 aa)
Mst84DdMale-specific sperm protein Mst84Dd; It is involved in the biological process described with: sperm axoneme assembly; spermatogenesis; Belongs to the MST(3)CGP family. (72 aa)
Mst84BUncharacterized protein, isoform B. (578 aa)
sowiIP07034p; Calcium ion binding. (217 aa)
CG10919IP07908p. (187 aa)
CG14718GH13594p; mRNA binding; transcription coregulator activity; RNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. (446 aa)
I-tInhibitor-t (I-t) encodes a protein phosphatase inhibitor. (184 aa)
ssp5Short spindle 5. (711 aa)
vrsGH03227p; It is involved in the biological process described with: chromatin organization. (387 aa)
CG8476J domain-containing protein. (242 aa)
CG3199FI08034p. (232 aa)
CG14355GH11706p. (1024 aa)
CG9920AT30951p; Chaperone binding; unfolded protein binding; metal ion binding. It is involved in the biological process described with: chaperone cofactor-dependent protein refolding; Belongs to the GroES chaperonin family. (102 aa)
CG7886Protein Cep78 homolog; May play a role in cilium biogenesis. Belongs to the CEP78 family. (818 aa)
CG14861EF-hand domain-containing protein; Calcium ion binding. (364 aa)
CG5614FI08029p; It is involved in the biological process described with: cilium assembly. (358 aa)
CG31244MIP05121p; Protein phosphatase 1 binding. (321 aa)
CG3581AT12577p. (253 aa)
Dic2Dicarboxylate carrier 2, isoform A; Belongs to the mitochondrial carrier (TC 2.A.29) family. (304 aa)
ThegCG6332 protein. (353 aa)
tHMG1Testis-enriched HMG-box-containing protein 1 (tHMG1) encodes a chromosomal protein involved in spermatogenesis. (126 aa)
Tpl94DTransition protein-like 94D (Tpl94D) encodes a HMG-box domain protein that is expressed during chromatin reorganization in spermatids. (164 aa)
CG10252CG10252 protein. (229 aa)
CG33340MIP30339p. (229 aa)
CG5762GH07296p. (200 aa)
CG5024GEO08667p1; Calcium ion binding; enzyme regulator activity. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. (165 aa)
CG3330Uncharacterized protein. (288 aa)
milAT14585p; Milkah (mil) encodes a nucleosome assembly factor of the Nap family. It is involved in spermatogenesis, long-term memory formation and male courtship. (283 aa)
Mst98CaMale-specific RNA 98Ca; It is involved in the biological process described with: spermatid development. (334 aa)
Mst98CbMale-specific RNA 98Cb; It is involved in the biological process described with: spermatid development. (265 aa)
Ppi1Protein phosphatase 1 binding. (998 aa)
ocnBcDNA.GH02250; Protein histidine phosphatase activity. It is involved in the biological process described with: peptidyl-histidine dephosphorylation. (148 aa)
CG2267GH11073p. (390 aa)
eIF4H2Translation initiation factor activity; nucleic acid binding; mRNA binding. It is involved in the biological process described with: translational initiation. (459 aa)
CG31204FI22218p1. (491 aa)
CG8517GEO08746p1; Protein disulfide oxidoreductase activity; disulfide oxidoreductase activity. It is involved in the biological process described with: glycerol ether metabolic process; cell redox homeostasis. (145 aa)
CG15124IP07030p. (191 aa)
CG15128FI19322p1. (580 aa)
CG10934GH26058p. (194 aa)
S-Lap8Sperm-Leucylaminopeptidase 8; Aminopeptidase activity; metalloexopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis. (534 aa)
CG5089GH06435p. (436 aa)
CG10734IP11711p. (368 aa)
CG12860Uncharacterized protein. (316 aa)
CG12861AT13777p. (239 aa)
S-Lap7Sperm-Leucylaminopeptidase 7, isoform A; Manganese ion binding; metalloexopeptidase activity; aminopeptidase activity. It is involved in the biological process described with: proteolysis; multicellular organism reproduction. (527 aa)
CG4712FI19336p1. (674 aa)
CG12902GEO08891p1. (64 aa)
CG30350GH17930p; Peptidyl-prolyl cis-trans isomerase activity. It is involved in the biological process described with: protein peptidyl-prolyl isomerization. (369 aa)
CG8701GH07855p. (246 aa)
CG2127AT21693p. (305 aa)
saltoUncharacterized protein, isoform A. (832 aa)
sut4Sugar transporter 4; Carbohydrate:proton symporter activity. It is involved in the biological process described with: glucose import; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (444 aa)
CG18449GEO12122p1. (159 aa)
djSperm-specific protein Don juan; May be involved in the final steps of mitochondrial differentiation within the flagellum. (248 aa)
CG9133AT07490p. (332 aa)
CG34168GEO13348p1. (60 aa)
loopin-1Loopin-1, isoform A; Loopin-1 (loopin-1) encodes a testis-specific protein with homology to several leucine aminopeptidases. Sequence analysis suggest that it doesn't have enzymatic activity. It accumulates inside the axoneme-associated mitochondrial derivative in mature sperms. (526 aa)
CG4836Uncharacterized protein, isoform E; L-iditol 2-dehydrogenase activity. It is involved in the biological process described with: oxidation-reduction process; sorbitol catabolic process. (1224 aa)
CG15109Uncharacterized protein, isoform E. (389 aa)
CG12699GH14656p. (145 aa)
tHMG2Testis-enriched HMG-box-containing protein 2 (tHMG2) encodes a chromosomal protein involved in spermatogenesis. (134 aa)
Prtl99CProtamine-like 99C (Prtl99C) encodes a sperm chromatin-associated protein that is essential for male fertility. It acts additively together with the products of Mst77F, ProtA and ProtB to compact the paternal chromatin; Belongs to the UPF0771 family. (201 aa)
CG43072GEO02514p1. (82 aa)
CG15219LP09525p. (119 aa)
CG17377Uncharacterized protein, isoform E. (207 aa)
CG15306Uncharacterized protein, isoform A; Microtubule plus-end binding; microtubule binding. It is involved in the biological process described with: spindle assembly; regulation of microtubule polymerization or depolymerization; protein localization to microtubule plus-end; protein localization to microtubule. (357 aa)
CG13243AT09889p. (405 aa)
Tektin-ATektin A, isoform A; It is involved in the biological process described with: cilium movement involved in cell motility; cilium assembly. (585 aa)
CG13245GH06096p. (80 aa)
CG8564Uncharacterized protein, isoform C; Zinc ion binding; metallocarboxypeptidase activity. It is involved in the biological process described with: proteolysis. (520 aa)
CG6380AT25465p; Protein phosphatase inhibitor activity. It is involved in the biological process described with: regulation of phosphoprotein phosphatase activity; regulation of signal transduction. (293 aa)
CG4983GH17939p. (367 aa)
CG13541IP06556p. (172 aa)
CG31988GH01042p; Transcription coregulator activity. (178 aa)
CG14926CG14926 protein. (174 aa)
CG18568GH18325p. (334 aa)
CG1394GH14622p. (167 aa)
CG6304GH09088p. (422 aa)
CG46059Uncharacterized protein, isoform A. (47 aa)
CG46298Uncharacterized protein, isoform A. (129 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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