node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MAPk-Ak2 | p38a | FBpp0292066 | FBpp0083966 | MAP kinase-activated protein kinase 2; Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25); Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | P38a MAP kinase (p38a) encodes a member of the mitogen-activated protein kinases responsive to diverse stresses. In immune response, it activates its downstream component encoded by Atf-2 that in turn regulates Duox expression. | 0.990 |
MAPk-Ak2 | p38b | FBpp0292066 | FBpp0080111 | MAP kinase-activated protein kinase 2; Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25); Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | P38b MAP kinase (p38b) encodes the serine/threonine kinase that constitutes MAP kinase signaling cascades. It is phosphorylated by MAPK kinases and phosphorylates various substrates that play roles in stress responses, immune responses and differentiation; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. | 0.988 |
MAPk-Ak2 | p38c | FBpp0292066 | FBpp0083967 | MAP kinase-activated protein kinase 2; Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25); Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | Putative mitogen-activated protein kinase 14C; P38c MAP kinase (p38c) encodes a protein involved in the stress and wound responses, regulating the expression of Duox and Ddc. | 0.606 |
Ras85D | Rgl | FBpp0081600 | FBpp0303219 | Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. | Ral guanine nucleotide dissociation stimulator-like, isoform E; Ral guanyl-nucleotide exchange factor activity; Ras GTPase binding. It is involved in the biological process described with: regulation of Ras protein signal transduction; small GTPase mediated signal transduction; activation of GTPase activity. | 0.972 |
Ras85D | p38b | FBpp0081600 | FBpp0080111 | Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. | P38b MAP kinase (p38b) encodes the serine/threonine kinase that constitutes MAP kinase signaling cascades. It is phosphorylated by MAPK kinases and phosphorylates various substrates that play roles in stress responses, immune responses and differentiation; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. | 0.452 |
Rgl | Ras85D | FBpp0303219 | FBpp0081600 | Ral guanine nucleotide dissociation stimulator-like, isoform E; Ral guanyl-nucleotide exchange factor activity; Ras GTPase binding. It is involved in the biological process described with: regulation of Ras protein signal transduction; small GTPase mediated signal transduction; activation of GTPase activity. | Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. | 0.972 |
p38a | MAPk-Ak2 | FBpp0083966 | FBpp0292066 | P38a MAP kinase (p38a) encodes a member of the mitogen-activated protein kinases responsive to diverse stresses. In immune response, it activates its downstream component encoded by Atf-2 that in turn regulates Duox expression. | MAP kinase-activated protein kinase 2; Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25); Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.990 |
p38a | p38b | FBpp0083966 | FBpp0080111 | P38a MAP kinase (p38a) encodes a member of the mitogen-activated protein kinases responsive to diverse stresses. In immune response, it activates its downstream component encoded by Atf-2 that in turn regulates Duox expression. | P38b MAP kinase (p38b) encodes the serine/threonine kinase that constitutes MAP kinase signaling cascades. It is phosphorylated by MAPK kinases and phosphorylates various substrates that play roles in stress responses, immune responses and differentiation; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. | 0.973 |
p38a | p38c | FBpp0083966 | FBpp0083967 | P38a MAP kinase (p38a) encodes a member of the mitogen-activated protein kinases responsive to diverse stresses. In immune response, it activates its downstream component encoded by Atf-2 that in turn regulates Duox expression. | Putative mitogen-activated protein kinase 14C; P38c MAP kinase (p38c) encodes a protein involved in the stress and wound responses, regulating the expression of Duox and Ddc. | 0.927 |
p38b | MAPk-Ak2 | FBpp0080111 | FBpp0292066 | P38b MAP kinase (p38b) encodes the serine/threonine kinase that constitutes MAP kinase signaling cascades. It is phosphorylated by MAPK kinases and phosphorylates various substrates that play roles in stress responses, immune responses and differentiation; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. | MAP kinase-activated protein kinase 2; Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25); Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.988 |
p38b | Ras85D | FBpp0080111 | FBpp0081600 | P38b MAP kinase (p38b) encodes the serine/threonine kinase that constitutes MAP kinase signaling cascades. It is phosphorylated by MAPK kinases and phosphorylates various substrates that play roles in stress responses, immune responses and differentiation; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. | Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. | 0.452 |
p38b | p38a | FBpp0080111 | FBpp0083966 | P38b MAP kinase (p38b) encodes the serine/threonine kinase that constitutes MAP kinase signaling cascades. It is phosphorylated by MAPK kinases and phosphorylates various substrates that play roles in stress responses, immune responses and differentiation; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. | P38a MAP kinase (p38a) encodes a member of the mitogen-activated protein kinases responsive to diverse stresses. In immune response, it activates its downstream component encoded by Atf-2 that in turn regulates Duox expression. | 0.973 |
p38b | p38c | FBpp0080111 | FBpp0083967 | P38b MAP kinase (p38b) encodes the serine/threonine kinase that constitutes MAP kinase signaling cascades. It is phosphorylated by MAPK kinases and phosphorylates various substrates that play roles in stress responses, immune responses and differentiation; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. | Putative mitogen-activated protein kinase 14C; P38c MAP kinase (p38c) encodes a protein involved in the stress and wound responses, regulating the expression of Duox and Ddc. | 0.927 |
p38c | MAPk-Ak2 | FBpp0083967 | FBpp0292066 | Putative mitogen-activated protein kinase 14C; P38c MAP kinase (p38c) encodes a protein involved in the stress and wound responses, regulating the expression of Duox and Ddc. | MAP kinase-activated protein kinase 2; Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25); Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.606 |
p38c | p38a | FBpp0083967 | FBpp0083966 | Putative mitogen-activated protein kinase 14C; P38c MAP kinase (p38c) encodes a protein involved in the stress and wound responses, regulating the expression of Duox and Ddc. | P38a MAP kinase (p38a) encodes a member of the mitogen-activated protein kinases responsive to diverse stresses. In immune response, it activates its downstream component encoded by Atf-2 that in turn regulates Duox expression. | 0.927 |
p38c | p38b | FBpp0083967 | FBpp0080111 | Putative mitogen-activated protein kinase 14C; P38c MAP kinase (p38c) encodes a protein involved in the stress and wound responses, regulating the expression of Duox and Ddc. | P38b MAP kinase (p38b) encodes the serine/threonine kinase that constitutes MAP kinase signaling cascades. It is phosphorylated by MAPK kinases and phosphorylates various substrates that play roles in stress responses, immune responses and differentiation; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. | 0.927 |