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CG3038 | Hexosyltransferase; Transferase activity, transferring hexosyl groups; acetylglucosaminyltransferase activity; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; acetylgalactosaminyltransferase activity. It is involved in the biological process described with: protein N-linked glycosylation; oligosaccharide biosynthetic process; protein O-linked glycosylation; protein glycosylation. (388 aa) | ||||
CG13369 | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (304 aa) | ||||
Pgd | 6-phosphogluconate dehydrogenase, decarboxylating; Phosphogluconate dehydrogenase (Pgd) encodes a cytosolic enzyme that catalyzes the oxidation of 6-phosphogluconate to ribulose 5-phosphate, with the concomitant reduction of NADP[+] to NADPH. The products of Pgd and Zw are the two NADP[+] reducing enzymes in the pentose phosphate pathway. (481 aa) | ||||
N | Processed neurogenic locus Notch protein; Essential signaling protein which has a major role in many developmental processes. Functions as a receptor for membrane-bound ligands Delta and Serrate to regulate cell-fate determination. Upon ligand activation, and releasing from the cell membrane, the Notch intracellular domain (NICD) forms a transcriptional activator complex with Su(H) (Suppressor of hairless) and activates genes of the E(spl) complex. Regulates oogenesis, the differentiation of the ectoderm and the development of the central and peripheral nervous system, eye, wing disk, [...] (2703 aa) | ||||
brn | Beta-1,3-galactosyltransferase brn; Neurogenic protein essential for the development and maintenance of epithelial structure. Required in the germline for establishing the follicular epithelium and for determining the dorsal- ventral polarity. Collaborates with Notch on the apical surface of follicle cells to mediate germline-follicle cell adhesion. Brn has a role in chorion formation. (325 aa) | ||||
GlcAT-I | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase I; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins. Shows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl, exhibiting negligible incorporation into other galactoside substrates; Belongs to the glycosyltransferase 43 family. (306 aa) | ||||
CG6903 | LD22376p; Transferase activity, transferring acyl groups. It is involved in the biological process described with: lysosomal transport. (576 aa) | ||||
CG16756 | GEO08277p1; Lysozyme activity. It is involved in the biological process described with: defense response to Gram-negative bacterium; Belongs to the glycosyl hydrolase 22 family. (152 aa) | ||||
Hexo2 | Beta-hexosaminidase; Hexosaminidase 2 (Hexo2) encodes a beta-N-acetylglucosaminidase involved in carbohydrate metabolism. (622 aa) | ||||
Hex-A | Phosphotransferase; Hexokinase A (Hex-A) encodes a hexokinase involved in glucose homeostasis. (541 aa) | ||||
MFS16 | Major facilitator superfamily transporter 16, isoform B; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (566 aa) | ||||
CG9485 | Uncharacterized protein, isoform B; 4-alpha-glucanotransferase activity; amylo-alpha-1,6-glucosidase activity. It is involved in the biological process described with: glycogen biosynthetic process; glycogen catabolic process. (1629 aa) | ||||
Taldo | Probable transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (331 aa) | ||||
Gale | UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP- Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconvers [...] (350 aa) | ||||
LysE | Lysozyme E; Unlikely to play an active role in the humoral immune defense. May have a function in the digestion of bacteria in the food; Belongs to the glycosyl hydrolase 22 family. (140 aa) | ||||
LysS | Lysozyme S; Unlikely to play an active role in the humoral immune defense. May have a function in the digestion of bacteria in the food; Belongs to the glycosyl hydrolase 22 family. (140 aa) | ||||
LysP | Lysozyme P; Unlikely to play an active role in the humoral immune defense. May have a function in the digestion of bacteria in the food. Belongs to the glycosyl hydrolase 22 family. (141 aa) | ||||
LysD | Lysozyme D; Unlikely to play an active role in the humoral immune defense. May have a function in the digestion of bacteria in the food. Belongs to the glycosyl hydrolase 22 family. (140 aa) | ||||
LysX | Lysozyme X; Unlikely to play an active role in the humoral immune defense. May have a function in the digestion of bacteria in the food. May be involved in the clearance of bacteria from the larval gut before metamorphosis; Belongs to the glycosyl hydrolase 22 family. (142 aa) | ||||
FucTD | Alpha-(1->3)-fucosyltransferase activity. It is involved in the biological process described with: fucosylation; protein glycosylation. (447 aa) | ||||
oxt | Xylosyltransferase oxt; Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes; Belongs to the glycosyltransferase 14 family. XylT subfamily. (876 aa) | ||||
Ids | Iduronate-2-sulfatase activity; sulfuric ester hydrolase activity. (512 aa) | ||||
Hexo1 | Beta-hexosaminidase; Hexosaminidase 1 (Hexo1) encodes a beta-N-acetylglucosaminidase involved in protein deglycosylation and rhodopsin biosynthesis. (622 aa) | ||||
CG17333 | Probable 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (243 aa) | ||||
Chsy | Hexosyltransferase; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity. (832 aa) | ||||
Gapdh2 | Glyceraldehyde 3 phosphate dehydrogenase 2 (Gapdh2) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glucose homeostasis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa) | ||||
Pfrx | 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase long form; ATP binding; 6-phosphofructo-2-kinase activity; fructose-2,6-bisphosphate 2-phosphatase activity. It is involved in the biological process described with: glycolytic process; fructose metabolic process; fructose 2,6-bisphosphate metabolic process; carbohydrate phosphorylation. (716 aa) | ||||
Zw | Glucose-6-phosphate 1-dehydrogenase; Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shunt, an alternative route to glycolysis for the dissimilation of carbohydrates and a major source of reducing power and metabolic intermediates for fatty acid and nucleic acid biosynthetic processes. (524 aa) | ||||
CG7328 | RE49431p; Carbohydrate kinase activity; fructokinase activity; ketohexokinase activity. (306 aa) | ||||
Papss | PAPS synthetase (Papss) encodes an enzyme that catalyzes the synthesis of 3'-phosphoadenosine 5'-phosphosulfate (PAPS), the sulfate donor compound in all sulfotransferase reactions. Maternally provided Papss product is required for the formation of the embryonic dorsal-ventral axis mediated by the sulfotransferase encoded by pip. (657 aa) | ||||
pip | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. (514 aa) | ||||
CG5103 | FI06132p; Transketolase activity; thiamine pyrophosphate binding. (623 aa) | ||||
CG12229 | AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process. (571 aa) | ||||
Papst2 | PAPS transporter 2 (Papst2) encodes the second transporter of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) and localizes in the cis-cisterna of the Golgi and the ER. It transfers PAPS from cytosol into the lumen of Golgi and ER. The product of Papst2 contributes to the sulfation of glycans and proteins, and is suggested to regulate several signaling pathways (Hh, Dpp, Wingless) mediated by glycosaminoglycans in development; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily. (396 aa) | ||||
Pgm1 | Phosphoglucomutase; This enzyme participates in both the breakdown and synthesis of glucose; Belongs to the phosphohexose mutase family. (560 aa) | ||||
FucTA | Glycoprotein 3-alpha-L-fucosyltransferase A; Alpha1,3-fucosyltransferase A (FucTA) encodes a Golgi fucosyltransferase that transfers fucose in alpha1,3-linkage to core N-acetylglucosamine residues of N-linked oligosaccharides. It is required for the synthesis of the anti-horseradish peroxidase epitope; Belongs to the glycosyltransferase 10 family. (503 aa) | ||||
dlp | Dally-like, isoform A; Dally-like (dlp) encodes a glypican that regulates the signaling strength and range of the morphogens encoded by hh and wg; Belongs to the glypican family. (765 aa) | ||||
GlcAT-P | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase P; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins. Enzyme has a broad specificity. (479 aa) | ||||
CG32055 | Uncharacterized protein. (534 aa) | ||||
sfl | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase; Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in diffusion of morphogen wingless (wg) via its role in heparan sulfate proteoglycans (HSPGs) biosynthesis, HSPGs being required for movement of wg morphogens. Required for wg signaling dur [...] (1048 aa) | ||||
CG2964 | Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process. (554 aa) | ||||
CG9961 | Phosphoglycerate kinase activity; ADP binding; ATP binding. It is involved in the biological process described with: positive regulation of oxidative phosphorylation; gluconeogenesis; glycolytic process. (448 aa) | ||||
GlyP | Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). Required for glycogen breakdown in skeletal muscle. (844 aa) | ||||
Got2 | Aspartate aminotransferase; Glutamate oxaloacetate transaminase 2 (Got2) encodes an L-aspartate:2-oxoglutarate aminotransferase involved in glutamate biosynthesis, which in turn regulates postsynaptic receptor field size. (431 aa) | ||||
Eno | Enolase (Eno) encodes a phosphopyruvate hydratase involved in glucose homeostasis; Belongs to the enolase family. (500 aa) | ||||
CG11249 | Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process. (642 aa) | ||||
beta-Man | Beta-Mannosidase, isoform A; Beta-mannosidase activity. It is involved in the biological process described with: glycoprotein catabolic process. (908 aa) | ||||
Oscillin | Identical protein binding; glucosamine-6-phosphate deaminase activity. (273 aa) | ||||
CG9550 | Sulfotransfer_1 domain-containing protein; N-acetylglucosamine 6-O-sulfotransferase activity. It is involved in the biological process described with: sulfur compound metabolic process; N-acetylglucosamine metabolic process. (363 aa) | ||||
CG31637 | LD35051p; N-acetylglucosamine 6-O-sulfotransferase activity. It is involved in the biological process described with: sulfur compound metabolic process; N-acetylglucosamine metabolic process. (486 aa) | ||||
Galt | Galactose-1-phosphate uridylyltransferase (Galt) encodes an enzyme that contributes to galactose homeostasis and adult locomotory behavior. (350 aa) | ||||
CG13397 | LP03571p; alpha-N-acetylglucosaminidase activity. (778 aa) | ||||
LManVI | Alpha-mannosidase activity; carbohydrate binding. It is involved in the biological process described with: protein deglycosylation; mannose metabolic process. (1007 aa) | ||||
Aldh | Aldehyde dehydrogenase (Aldh) encodes an NAD[+] dependent mitochondrial aldehyde dehydrogenase. Its functions include detoxifying endogenous aldehydes generated by lipid peroxidation, and detoxifying acetaldehyde derived from dietary ethanol. (520 aa) | ||||
CG6201 | LD15174p; L-iduronidase activity; hydrolase activity, hydrolyzing O-glycosyl compounds. It is involved in the biological process described with: carbohydrate metabolic process. (636 aa) | ||||
CG31743 | Sulfotransferase activity. It is involved in the biological process described with: carbohydrate biosynthetic process. (329 aa) | ||||
Hs2st | Heparan sulfate 2-O-sulfotransferase (Hs2st) encodes a heparan sulfate modifying enzyme, which transfers a sulfate group to 2-O position of glucuronic or iduronic acid residues of heparan sulfate. Loss of Hs2st function eliminates 2-O sulfation, but increases 6-O sulfation performed by the product of Hs6st. Simultaneous elimination of Hs6st and Hs2st functions disrupts FGF, Wg and Dpp signaling pathways. (349 aa) | ||||
vls | Protein valois; Involved in specific localization of cytoplasmic proteins during the formation of pole plasm. Required for synthesis and/or stability of oskar protein (osk) and localization of tudor (tud) in both the nuage and posterior pole of the oocyte. Required for normal posterior localization of osk in later stages of oogenesis and for posterior localization of the vasa (vas) protein during the entire process of pole plasm assembly. May act by regulating the complex that contains the arginine N-methyltransferase csul. (367 aa) | ||||
CG8036 | LP07963p; Transketolase activity; thiamine pyrophosphate binding. It is involved in the biological process described with: regulation of chromatin silencing. (626 aa) | ||||
Sodh-2 | Sorbitol dehydrogenase-2; L-iditol 2-dehydrogenase activity; zinc ion binding. It is involved in the biological process described with: oxidation-reduction process; sorbitol catabolic process. (360 aa) | ||||
Ect3 | Beta-galactosidase activity. It is involved in the biological process described with: carbohydrate metabolic process. (637 aa) | ||||
Pglym87 | Phosphoglycerate mutase activity. It is involved in the biological process described with: glycolytic process; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (292 aa) | ||||
GlyS | Glycogen synthase (GlyS) encodes a glycosyltransferase that catalyzes linkage of glucose monomers into glycogen. Regulation of the product of GlyS activity by glucose 6-phosphate and phosphorylation helps control cellular glycogen levels. (709 aa) | ||||
CG3534 | LD23605p; Xylulokinase activity; phosphotransferase activity, alcohol group as acceptor. It is involved in the biological process described with: phosphorylation; xylulose metabolic process; carbohydrate phosphorylation. (552 aa) | ||||
Mdh2 | Malate dehydrogenase 2 (Mdh2) encodes one of the enzymes in the tricarboxylic acid cycle in mitochondria; Belongs to the LDH/MDH superfamily. (336 aa) | ||||
CG14309 | Uncharacterized protein. (966 aa) | ||||
Sgsh | RE63280p; Sulfuric ester hydrolase activity; N-acetylglucosamine-6-sulfatase activity; glycosaminoglycan binding; N-sulfoglucosamine sulfohydrolase activity. It is involved in the biological process described with: heparan sulfate proteoglycan catabolic process; glycosaminoglycan catabolic process. (524 aa) | ||||
PyK | Pyruvate kinase (PyK) encodes an enzyme involved in muscle development, glycolysis and glucose homeostasis; Belongs to the pyruvate kinase family. (533 aa) | ||||
CG7069 | Pyruvate kinase activity; potassium ion binding; magnesium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process. (744 aa) | ||||
CG7059 | Phosphoglycerate mutase activity. It is involved in the biological process described with: glycolytic process; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (267 aa) | ||||
beta4GalT7 | Beta-4-galactosyltransferase 7 (beta4GalT7) encodes an enzyme that transfers a Gal to the Xyl-O-Ser in the tetrasaccharide structure of the protein-linkage region of glycosaminoglycans (GAGs). It is involved in Hh and Dpp signaling pathways mediated by GAGs in development. (322 aa) | ||||
Ald1 | Fructose-bisphosphate aldolase; May take part in developmental stage-specific or tissue -specific sugar-phosphate metabolisms. Protein acts on two substrates fructose 1,6-bisphosphate and fructose 1-phosphate (like other class I aldolases). (363 aa) | ||||
Ald2 | Fructose-bisphosphate aldolase activity. It is involved in the biological process described with: fructose 1,6-bisphosphate metabolic process; glycolytic process. (364 aa) | ||||
Hex-t1 | Hexokinase type 1; Catalyzes the phosphorylation of various hexoses to hexose 6- phosphate. (465 aa) | ||||
Hex-t2 | Hexokinase type 2; Catalyzes the phosphorylation of various hexoses to hexose 6- phosphate. (486 aa) | ||||
Pglym78 | Phosphoglyceromutase 78 (Pglym78) encodes an enzyme involved in myoblast fusion and somatic muscle development; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (255 aa) | ||||
beta4GalNAcTB | beta1,4-N-acetylgalactosaminyltransferase B (beta4GalNAcTB) encodes a Golgi glycosyltransferase that transfers N-acetylgalactosamine to N-acetylglucosamine residues of glycosphingolipids. (323 aa) | ||||
CG1907 | SD09259p; Oxoglutarate:malate antiporter activity. It is involved in the biological process described with: alpha-ketoglutarate transport; mitochondrial transport; malate transport; Belongs to the mitochondrial carrier (TC 2.A.29) family. (317 aa) | ||||
Tpi | Triose phosphate isomerase (Tpi) encodes a soluble metabolic protein dimer that functions in glycolysis catalyzing the isomerization between dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, which is essential for efficient ATP production. (348 aa) | ||||
CG11159 | GEO12014p1; Lysozyme activity. It is involved in the biological process described with: defense response to Gram-negative bacterium; Belongs to the glycosyl hydrolase 22 family. (146 aa) | ||||
CG15117 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (670 aa) | ||||
Pepck1 | Phosphoenolpyruvate carboxykinase 1 (Pepck1) encodes an enzyme that converts oxaloacetate into phosphoenolpyruvate. It catalyzes the first committed step in gluconeogenesis and thus plays an essential role in glucose metabolism. (647 aa) | ||||
CG9010 | Glyceraldehyde-3-phosphate dehydrogenase; Peptidyl-cysteine S-nitrosylase activity; NADP binding; NAD binding; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. It is involved in the biological process described with: oxidation-reduction process; glycolytic process; glucose metabolic process. (343 aa) | ||||
CG7798 | GEO02684p1; Lysozyme activity. It is involved in the biological process described with: defense response to Gram-negative bacterium; Belongs to the glycosyl hydrolase 22 family. (148 aa) | ||||
Got1 | Glutamate oxaloacetate transaminase 1 (Got1) encodes an L-aspartate:2-oxoglutarate aminotransferase involved in glutamate biosynthesis. (437 aa) | ||||
Hex-C | Phosphotransferase; Hexokinase C (Hex-C) encodes a hexokinase involved in glucose homeostasis. (454 aa) | ||||
Pgm2b | Phosphoglucomutase 2b; Intramolecular transferase activity, phosphotransferases. It is involved in the biological process described with: carbohydrate metabolic process. (628 aa) | ||||
beta4GalNAcTA | beta1,4-N-acetylgalactosaminyltransferase A (beta4GalNAcTA) encodes a acetylgalactosaminyltransferase involved in glycolipid biosynthesis. It contributes to the development of the neuromuscular junction. (403 aa) | ||||
CG18278 | SD21168p; Glycosaminoglycan binding; N-acetylglucosamine-6-sulfatase activity. It is involved in the biological process described with: glycosaminoglycan metabolic process. (492 aa) | ||||
AGBE | 1,4-Alpha-Glucan Branching Enzyme (AGBE) encodes a protein that is inferred to be a hydrolase involved in glycogen synthesis and hypoxia, based on the function of its orthologs. It contributes to the determination of lifespan. (685 aa) | ||||
Dera | Deoxyribose-phosphate aldolase activity. It is involved in the biological process described with: carbohydrate catabolic process; deoxyribonucleotide catabolic process. (347 aa) | ||||
fdl | Probable beta-hexosaminidase fdl; Involved in brain restructurization via hormonal control during metamorphosis. Implicated in N-glycan processing. Belongs to the glycosyl hydrolase 20 family. (673 aa) | ||||
GalT1 | Hexosyltransferase; Beta1,3-galactosyltransferase 1 (GalT1) encodes an enzyme involved in protein N-linked glycosylation. (466 aa) | ||||
CG30037 | Hexosyltransferase; Acetylgalactosaminyltransferase activity; acetylglucosaminyltransferase activity; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; transferase activity, transferring hexosyl groups. It is involved in the biological process described with: protein N-linked glycosylation; protein glycosylation; protein O-linked glycosylation; oligosaccharide biosynthetic process. (420 aa) | ||||
CG30036 | Hexosyltransferase; Transferase activity, transferring hexosyl groups; acetylgalactosaminyltransferase activity; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; acetylglucosaminyltransferase activity. It is involved in the biological process described with: protein N-linked glycosylation; oligosaccharide biosynthetic process; protein glycosylation; protein O-linked glycosylation. (388 aa) | ||||
Pfk | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (950 aa) | ||||
PCB | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1197 aa) | ||||
Pgm2a | Phosphoglucomutase 2a; Magnesium ion binding; intramolecular transferase activity, phosphotransferases. It is involved in the biological process described with: carbohydrate metabolic process. (623 aa) | ||||
Pgi | Phosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis. (558 aa) | ||||
beta3GalTII | Hexosyltransferase; beta-1,3-Galactosyltransferase II (beta3GalTII) encodes a protein involved in the synthesis of a common linkage tetrasaccharide structure of heparan (HS) and chondroitin sulfates (CS). Its roles include regulation of several signaling pathways (Hh, Dpp, Wingless) mediated by HS and CS in development. (382 aa) | ||||
sut1 | Sugar transporter 1; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (507 aa) | ||||
sut2 | Sugar transporter 2; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (491 aa) | ||||
sut3 | Sugar transporter 3, isoform A; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; glucose homeostasis; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (476 aa) | ||||
azot | GEO08584p1; Ahuizotl (azot) encodes a calcium dependent protein that ensures the elimination of less fit cells. Fitness-based cell culling is used to maintain tissue health, delay aging, and extend lifespan. During development it also prevents malformations; Belongs to the calmodulin family. (148 aa) | ||||
Gapdh1 | Glyceraldehyde 3 phosphate dehydrogenase 1 (Gapdh1) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glycolysis, myoblast fusion and the development of somatic muscle. (332 aa) | ||||
Rpe | Metal ion binding; ribulose-phosphate 3-epimerase activity. It is involved in the biological process described with: cellular carbohydrate metabolic process; pentose catabolic process; pentose-phosphate shunt, non-oxidative branch. (221 aa) | ||||
UGP | UTP--glucose-1-phosphate uridylyltransferase; UGP (UGP) encodes an enzyme involved in hyperoxia response. (520 aa) | ||||
sea | Scheggia, isoform A; Scheggia (sea) encodes a carrier protein of the inner mitochondrial membrane that plays a central role in fatty acid and sterol biosynthesis. It catalyses an electroneutral exchange of citrate for another tricarboxylate, a dicarboxylate (L-malate), or phosphoenolpyruvate across the inner mitochondrial membrane. The product of sea is also required to prevent chromosome breaks. (317 aa) | ||||
sotv | Exostosin-2; Glycosyltransferase required for the biosynthesis of heparan- sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. Plays a central role in diffusion of morphogens hedgehog (hh), wingless (wg) and Decapentaplegic (dpp) via its role in heparan sulfate proteoglycans (HSPGs) biosynthesis, HSPGs being required for movement of Hh, Dpp and wg morphogens. (717 aa) | ||||
G6P | Glucose-6-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; glucose 6-phosphate metabolic process. (350 aa) | ||||
CG11357 | Hexosyltransferase; Transferase activity, transferring hexosyl groups; galactosyltransferase activity; acetylglucosaminyltransferase activity; acetylgalactosaminyltransferase activity. It is involved in the biological process described with: protein O-linked glycosylation; protein glycosylation. (434 aa) | ||||
frc | UDP-sugar transporter UST74c; Involved in the import of UDP-sugars from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35D subfamily. (373 aa) | ||||
FucTC | Fucosyltransferase activity; alpha-(1->3)-fucosyltransferase activity. It is involved in the biological process described with: fucosylation; protein glycosylation; Belongs to the glycosyltransferase 10 family. (425 aa) | ||||
kon | Kon-tiki, isoform B; Kon-tiki (kon) (also known as perdido) encodes a single transmembrane protein required to initiate muscle-tendon attachment in a group of embryonic and adult body muscles. kon mutants are embryonic lethal with rounded ventral longitudinal muscles. It concentrates at muscle attachment sites and genetically interacts with integrins. (2381 aa) | ||||
CG13937 | Sulfotransferase activity. It is involved in the biological process described with: carbohydrate biosynthetic process. (431 aa) | ||||
GlcAT-S | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase S; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins. Enzyme has a broad specificity. (486 aa) | ||||
LManIV | Alpha-mannosidase; Carbohydrate binding; alpha-mannosidase activity. It is involved in the biological process described with: protein deglycosylation; mannose metabolic process. (978 aa) | ||||
CG30062 | IP06881p; Lysozyme activity. It is involved in the biological process described with: defense response to Gram-negative bacterium; Belongs to the glycosyl hydrolase 22 family. (171 aa) | ||||
CG18095 | Uncharacterized protein, isoform B. (564 aa) | ||||
sll | Slalom (sll) encodes the first transporter of 3'-phosphoadenosine 5'-phosphosulfate (PAPS), that transfers PAPS from cytosol into the lumen of Golgi. It contributes to the sulfation of glycans and proteins, the regulation of several signaling pathways (Hh, Wingless) mediated by glycosaminoglycans during patterning and morphogenesis, and the determination of the embryonic dorsal/ventral axis; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily. (465 aa) | ||||
CG3253 | GH04269p; Glucuronosyltransferase activity. It is involved in the biological process described with: protein O-linked mannosylation. (389 aa) | ||||
Rpi | Ribose-5-phosphate isomerase activity. It is involved in the biological process described with: age-dependent response to reactive oxygen species; D-ribose metabolic process; pentose-phosphate shunt, non-oxidative branch. (241 aa) | ||||
dally | Division abnormally delayed (dally) encodes a core protein of heparan sulfate proteoglycans of the glypican family. It acts as a co-receptor for growth factors and morphogens, such as the products of dpp, wg, hh, upd1 and FGFs, affecting signaling and distribution of these ligands. The roles of the product of dally include wing development and germline stem cell maintenance. (626 aa) | ||||
aralar1 | Calcium-binding mitochondrial carrier protein Aralar1; Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. (707 aa) | ||||
CG31075 | Uncharacterized protein, isoform B; Aldehyde dehydrogenase (NAD+) activity. It is involved in the biological process described with: oxidation-reduction process; pyruvate metabolic process. (508 aa) | ||||
CG7766 | Probable phosphorylase b kinase regulatory subunit alpha; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin (By similarity). (1358 aa) | ||||
LManI | Lysosomal alpha-mannosidase I (LManI) encodes an enzyme that is involved in mannose metabolism using p-nitrophenyl-alpha-mannoside as a substrate. (950 aa) | ||||
CG14024 | Sulfotransferase activity. It is involved in the biological process described with: carbohydrate biosynthetic process. (444 aa) | ||||
CG7362 | Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process. (793 aa) | ||||
Hs3st-B | Heparan sulfate 3-O sulfotransferase-B (Hs3st-B) encodes a heparan sulfate modifying enzyme that transfers a sulfate group to the 3-O position of glucosamine residues of heparan sulfate. It regulates adult midgut homeostasis. (384 aa) | ||||
Gbs-70E | Protein phosphatase 1 regulatory subunit; Glycogen binding subunit 70E (Gbs-70E) is one of the glycogen binding subunits of protein phosphatase 1 (Pp1) that interacts with all of the known Pp1 catalytic subunits (encoded by Pp1-87B, flw, Pp1alpha-96A, and Pp1-13C). The product of Gbs-70E is involved in the regulation of glycogen metabolism, and plays a role in the egg development. (384 aa) | ||||
Glut1 | Glucose transporter 1 (Glut1) encodes a transmembrane protein that transports glucose but not galactose. (1440 aa) | ||||
Pgk | Phosphoglycerate kinase (Pgk) encodes an enzyme involved in myoblast fusion; Belongs to the phosphoglycerate kinase family. (415 aa) | ||||
CG8475 | Probable phosphorylase b kinase regulatory subunit beta; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation (By similarity). (1098 aa) | ||||
Hs6st | Heparan sulfate 6-O-sulfotransferase (Hs6st) encodes a heparan sulfate modifying enzyme, which transfers a sulfate group to the 6-O position of glucosamine residues of heparan sulfate. Loss of Hs6st eliminates 6-O sulfation, but increases 2-O sulfation performed by the product of Hs2st. Simultaneous elimination of Hs6st and Hs2st disrupts FGF, Wg and Dpp signaling pathways. (462 aa) | ||||
CG7882 | IP16073p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (516 aa) | ||||
CG9886 | Glycerate kinase activity. It is involved in the biological process described with: protein phosphorylation; Belongs to the glycerate kinase type-2 family. (487 aa) | ||||
LysB | Lysozyme B; Unlikely to play an active role in the humoral immune defense. May have a function in the digestion of bacteria in the food; Belongs to the glycosyl hydrolase 22 family. (140 aa) | ||||
Gyg | Glycogenin, isoform E; Glycogenin glucosyltransferase activity. It is involved in the biological process described with: glycogen biosynthetic process. (699 aa) | ||||
Csgalnact | Hexosyltransferase; Glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. It is involved in the biological process described with: wound healing. (540 aa) | ||||
LManIII | Alpha-mannosidase activity; carbohydrate binding. It is involved in the biological process described with: mannose metabolic process; protein deglycosylation. (1003 aa) | ||||
CG16799 | Uncharacterized protein, isoform A; Lysozyme activity. It is involved in the biological process described with: defense response to Gram-negative bacterium; Belongs to the glycosyl hydrolase 22 family. (179 aa) | ||||
Sdc | Syndecan (Sdc) encodes a transmembrane heparan sulfate proteoglycan. It binds to the products of sli and robo1 to regulate axon guidance at the CNS midline, and it cooperates with the product of Lar to promote synapse growth at the larval neuromuscular junction. (495 aa) | ||||
CG10638 | Uncharacterized protein, isoform A; Alcohol dehydrogenase (NADP+) activity; oxidoreductase activity; alditol:NADP+ 1-oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. (317 aa) | ||||
Mdh1 | Malate dehydrogenase 1 (Mdh1) encodes a L-malate dehydrogenase involved in the interconversion of malate and oxaloacetate. (337 aa) | ||||
Hs3st-A | Heparan sulfate 3-O sulfotransferase-A (Hs3st-A) encodes a heparan sulfate modifying enzyme that transfers a sulfate group to the 3-O position of glucosamine residues of heparan sulfate. It regulates adult midgut homeostasis by repressing EGFR signaling. (605 aa) | ||||
LManV | Alpha-mannosidase activity; carbohydrate binding. It is involved in the biological process described with: mannose metabolic process; protein deglycosylation. (982 aa) | ||||
CG7322 | RH57257p; Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; carbonyl reductase (NADPH) activity; L-xylulose reductase (NADP+) activity. It is involved in the biological process described with: xylulose metabolic process; glucose metabolic process. (242 aa) | ||||
Had1 | Beta hydroxy acid dehydrogenase 1, isoform A; NAD+ binding; L-gulonate 3-dehydrogenase activity; 3-hydroxyacyl-CoA dehydrogenase activity. It is involved in the biological process described with: oxidation-reduction process; fatty acid metabolic process. (315 aa) | ||||
Dic1 | Dicarboxylate carrier 1 (Dic1) encodes a protein of the inner mitochondrial membrane that catalyzes an electroneutral exchange across the inner mitochondrial membrane of dicarboxylates (e.g. malonate, malate, succinate) for inorganic phosphate and certain sulfur-containing compounds (e.g. sulfite, sulfate, thiosulfate). The main role of the product of is in gluconeogenesis. The carrier protein has also an anaplerotic role supplying substrates for the Krebs cycle. (280 aa) | ||||
Chpf | Hexosyltransferase; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. (819 aa) | ||||
FucTB | Alpha-(1,3)-fucosyltransferase B; Alpha-(1->3)-fucosyltransferase activity. It is involved in the biological process described with: fucosylation; protein glycosylation; Belongs to the glycosyltransferase 10 family. (444 aa) | ||||
fbp | Fructose-1,6-bisphosphatase, isoform F; Fructose 1,6-bisphosphate 1-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; fructose 6-phosphate metabolic process; fructose metabolic process; fructose 1,6-bisphosphate metabolic process; sucrose biosynthetic process; Belongs to the FBPase class 1 family. (343 aa) | ||||
ttv | Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. Botv is the trigger of heparan sulfate chain initiation and polymerization takes place by a complex of ttv and sotv. Plays a central role in the diffusion of morphogens hedgehog (hh), wingless (wg) and decapentaplegic (dpp) via its role in heparan sulfate proteoglycans (HSPGs) biosynthesis which are required for movement of hh, d [...] (772 aa) |