node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG15725 | CG7148 | FBpp0073518 | FBpp0078102 | Uncharacterized protein; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | GH10766p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | 0.900 |
CG15725 | Cul1 | FBpp0073518 | FBpp0087922 | Uncharacterized protein; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Cullin homolog 1; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larv [...] | 0.499 |
CG15725 | Roc1a | FBpp0073518 | FBpp0300874 | Uncharacterized protein; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | RING-box protein 1A; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Required for the specific SCF-dependent proteolysis of CI, but not that of ARM, suggesting that it also participates in the selection of substrates inside the SCF complex. During early metamorphosis, part of [...] | 0.499 |
CG15725 | RpL40 | FBpp0073518 | FBpp0306837 | Uncharacterized protein; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] | 0.553 |
CG15725 | RpS27A | FBpp0073518 | FBpp0079606 | Uncharacterized protein; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involve [...] | 0.545 |
CG15725 | Skp2 | FBpp0073518 | FBpp0078593 | Uncharacterized protein; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | S-phase kinase-associated protein 2 (Skp2) encodes the substrate recognizing component of the SCF-Skp2 ubiquitin ligase. It functions with the product of Cks85A to target the product of dap for destruction. It is required for larval growth and to maintain diploidy in imaginal tissues. | 0.499 |
CG15725 | SkpA | FBpp0073518 | FBpp0099971 | Uncharacterized protein; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | SKP1-related A (SkpA) encodes a subunit of Skp, Cullin, F-box (SCF)-containing ubiquitin ligase complexes. It regulates centrosome duplication, chromatin condensation, cell cycle progression, cell polarity, dendrite pruning and endoreduplication. | 0.504 |
CG15725 | Ubi-p5E | FBpp0073518 | FBpp0311816 | Uncharacterized protein; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Ubiquitin-5E, isoform A; Protein tag; ubiquitin protein ligase binding. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; protein ubiquitination; modification-dependent protein catabolic process; cellular protein modification process. | 0.536 |
CG15725 | Ubi-p63E | FBpp0073518 | FBpp0073035 | Uncharacterized protein; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Polyubiquitin; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradatio [...] | 0.536 |
CG15725 | maf-S | FBpp0073518 | FBpp0309590 | Uncharacterized protein; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Maf-S, isoform B; DNA-binding transcription factor activity; sequence-specific DNA binding; protein heterodimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II; head development. | 0.900 |
CG7148 | CG15725 | FBpp0078102 | FBpp0073518 | GH10766p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | Uncharacterized protein; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | 0.900 |
CG7148 | Cul1 | FBpp0078102 | FBpp0087922 | GH10766p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | Cullin homolog 1; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larv [...] | 0.696 |
CG7148 | Roc1a | FBpp0078102 | FBpp0300874 | GH10766p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | RING-box protein 1A; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Required for the specific SCF-dependent proteolysis of CI, but not that of ARM, suggesting that it also participates in the selection of substrates inside the SCF complex. During early metamorphosis, part of [...] | 0.400 |
CG7148 | RpL40 | FBpp0078102 | FBpp0306837 | GH10766p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] | 0.499 |
CG7148 | RpS27A | FBpp0078102 | FBpp0079606 | GH10766p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involve [...] | 0.499 |
CG7148 | Skp2 | FBpp0078102 | FBpp0078593 | GH10766p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | S-phase kinase-associated protein 2 (Skp2) encodes the substrate recognizing component of the SCF-Skp2 ubiquitin ligase. It functions with the product of Cks85A to target the product of dap for destruction. It is required for larval growth and to maintain diploidy in imaginal tissues. | 0.400 |
CG7148 | SkpA | FBpp0078102 | FBpp0099971 | GH10766p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | SKP1-related A (SkpA) encodes a subunit of Skp, Cullin, F-box (SCF)-containing ubiquitin ligase complexes. It regulates centrosome duplication, chromatin condensation, cell cycle progression, cell polarity, dendrite pruning and endoreduplication. | 0.600 |
CG7148 | Ubi-p5E | FBpp0078102 | FBpp0311816 | GH10766p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | Ubiquitin-5E, isoform A; Protein tag; ubiquitin protein ligase binding. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; protein ubiquitination; modification-dependent protein catabolic process; cellular protein modification process. | 0.499 |
CG7148 | Ubi-p63E | FBpp0078102 | FBpp0073035 | GH10766p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | Polyubiquitin; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradatio [...] | 0.499 |
CG7148 | maf-S | FBpp0078102 | FBpp0309590 | GH10766p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | Maf-S, isoform B; DNA-binding transcription factor activity; sequence-specific DNA binding; protein heterodimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II; head development. | 0.499 |