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clt clt Nrt Nrt Est-P Est-P CG5592 CG5592 SLC22A SLC22A CG7458 CG7458 Oatp30B Oatp30B CarT CarT Ace Ace CG14855 CG14855 CG14856 CG14856 CG14857 CG14857 CG8925 CG8925 CG6126 CG6126 CG17752 CG17752 CG16727 CG16727 CG6231 CG6231 CG4459 CG4459 CG4462 CG4462 CG4465 CG4465 Orct Orct CG6356 CG6356 Jhedup Jhedup Jhe Jhe Balat Balat CG6006 CG6006 CG4382 CG4382 CG7333 CG7333 CG10486 CG10486 CG17751 CG17751 CG42269 CG42269 CG7342 CG7342 CG4630 CG4630 Est-6 Est-6 Orct2 Orct2 CG4757 CG4757 CG5397 CG5397 CG10175 CG10175 CG8654 CG8654 CG7084 CG7084 CG44098 CG44098 CG6414 CG6414
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
cltRelated juvenile hormone esterase; Carboxylic ester hydrolase activity. It is involved in the biological process described with: male mating behavior. (562 aa)
NrtNeurotactin; May mediate or modulate cell adhesion between embryonic cells during development; In the C-terminal section; belongs to the type-B carboxylesterase/lipase family. (846 aa)
Est-PEsterase P; Carboxylic ester hydrolase activity; Belongs to the type-B carboxylesterase/lipase family. (544 aa)
CG5592MFS domain-containing protein; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (540 aa)
SLC22ASLC22A family member (SLC22A) encodes a plasma membrane transporter and a member of the conserved family of SLC22A transporters. The product of SLC22A is preferentially localized in the dendrites of mushroom body neurons, where it functions to terminate synaptic transmission from cholinergic projection neurons through uptake of the released neurotransmitter acetylcholine. Impairing the function of SLC22A enhances the acquisition and retention of olfactory memory by allowing the neurotransmitter signal from projection neurons to be more persistent. (568 aa)
CG7458FI24011p1; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (572 aa)
Oatp30BOrganic anion transporting polypeptide 30B (Oatp30B) encodes a transmembrane transporter involved in the transport of the cardiac glycoside ouabain. (1197 aa)
CarTCarcinine transporter (CarT) encodes a transporter belonging to the SLC22A transporter family that is involved in the photoreceptor histamine-carcinine cycle. Histamine neurotransmitter is released by photoreceptors and cleared by uptake into glia, where it is converted to carcinine. The product of CarT transports carcinine back to photoreceptors, where it is hydrolysed by the product of t to restore the pool of histamine; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. (674 aa)
AceAcetylcholinesterase 16 kDa subunit; Acetylcholine esterase (Ace) encodes an enzyme that catalyzes the hydrolysis of the neurotransmitter acetylcholine to acetate and choline, thus resetting the neurotransmission mechanism at neuromuscular junctions; Belongs to the type-B carboxylesterase/lipase family. (649 aa)
CG14855MFS domain-containing protein; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (556 aa)
CG14856FI01439p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (557 aa)
CG14857MFS domain-containing protein; It is involved in the biological process described with: transmembrane transport. (560 aa)
CG8925Uncharacterized protein, isoform A; Transporter activity. It is involved in the biological process described with: transmembrane transport. (670 aa)
CG6126GH09241p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (555 aa)
CG17752LP04053p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (538 aa)
CG16727LP02775p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (545 aa)
CG6231FI18650p1; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (585 aa)
CG4459Uncharacterized protein; It is involved in the biological process described with: transmembrane transport. (632 aa)
CG4462IP21853p; It is involved in the biological process described with: transmembrane transport. (573 aa)
CG4465Uncharacterized protein; It is involved in the biological process described with: transmembrane transport. (577 aa)
OrctOrganic cation transporter protein; Probably transports organic cations. (548 aa)
CG6356FI05810p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (570 aa)
JhedupCarboxylic ester hydrolase activity; Belongs to the type-B carboxylesterase/lipase family. (559 aa)
JheCarboxylic ester hydrolase; Juvenile hormone esterase (Jhe) encodes a juvenile-hormone esterase involved in response to ethanol, juvenile hormone catabolism and male mating behavior; Belongs to the type-B carboxylesterase/lipase family. (579 aa)
BalatBeta-alanine transporter; Beta-alanine transporter required for the uptake of beta- alanine by the glia. Required for the recycling process of the neurotransmitter histamine in photoreceptor neurons of the compound eye and therefore for photoreceptor synaptic transmission. Following histamine release from photoreceptors and its uptake by glia, histamine is conjugated to beta-alanine by e/Ebony to form the inactive metabolite, carcinine. (604 aa)
CG6006IP17430p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (603 aa)
CG4382FI17410p1; Carboxylic ester hydrolase activity. (580 aa)
CG7333MFS domain-containing protein; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (541 aa)
CG10486Uncharacterized protein, isoform B; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (706 aa)
CG17751MFS domain-containing protein; It is involved in the biological process described with: transmembrane transport. (533 aa)
CG42269MFS domain-containing protein; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (662 aa)
CG7342IP21962p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (540 aa)
CG4630Uncharacterized protein, isoform B; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (582 aa)
Est-6Esterase-6; Transferred from the ejaculatory bulbs of males to the female genitals upon copulation, plays an important role in the reproductive biology. (544 aa)
Orct2Organic cation transporter 2 (Orct2) encodes an organic cation transporter of the major facilitator superfamily, and a transcriptional target of the insulin receptor pathway. (567 aa)
CG4757Carboxylic ester hydrolase activity; Belongs to the type-B carboxylesterase/lipase family. (550 aa)
CG5397GH04232p; Carboxylic ester hydrolase activity. (665 aa)
CG10175Uncharacterized protein, isoform D; Carboxylic ester hydrolase activity; Belongs to the type-B carboxylesterase/lipase family. (707 aa)
CG8654MIP15932p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (502 aa)
CG7084RH23644p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (597 aa)
CG44098MIP13952p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (813 aa)
CG6414Carboxylic ester hydrolase activity; Belongs to the type-B carboxylesterase/lipase family. (583 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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