STRINGSTRING
Hex-A Hex-A CG10996 CG10996 Gapdh2 Gapdh2 Zw Zw CG6650 CG6650 CG10467 CG10467 CG9961 CG9961 Eno Eno CG32444 CG32444 CG32445 CG32445 CG4988 CG4988 Hex-t1 Hex-t1 Hex-t2 Hex-t2 Tpi Tpi Pepck2 Pepck2 Pepck1 Pepck1 CG9010 CG9010 Hex-C Hex-C Pfk Pfk PCB PCB Pgi Pgi Gapdh1 Gapdh1 G6P G6P CG3552 CG3552 CG7140 CG7140 PhKgamma PhKgamma Pgk Pgk CG7322 CG7322 fbp fbp Gld Gld
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Hex-APhosphotransferase; Hexokinase A (Hex-A) encodes a hexokinase involved in glucose homeostasis. (541 aa)
CG10996Uncharacterized protein; Carbohydrate binding; aldose 1-epimerase activity. It is involved in the biological process described with: galactose catabolic process via UDP-galactose; glucose metabolic process. (392 aa)
Gapdh2Glyceraldehyde 3 phosphate dehydrogenase 2 (Gapdh2) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glucose homeostasis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
ZwGlucose-6-phosphate 1-dehydrogenase; Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shunt, an alternative route to glycolysis for the dissimilation of carbohydrates and a major source of reducing power and metabolic intermediates for fatty acid and nucleic acid biosynthetic processes. (524 aa)
CG6650LD24362p; ADP-specific glucokinase activity. It is involved in the biological process described with: carbohydrate metabolic process. (501 aa)
CG10467Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (364 aa)
CG9961Phosphoglycerate kinase activity; ADP binding; ATP binding. It is involved in the biological process described with: positive regulation of oxidative phosphorylation; gluconeogenesis; glycolytic process. (448 aa)
EnoEnolase (Eno) encodes a phosphopyruvate hydratase involved in glucose homeostasis; Belongs to the enolase family. (500 aa)
CG32444Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (370 aa)
CG32445Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (367 aa)
CG4988Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (368 aa)
Hex-t1Hexokinase type 1; Catalyzes the phosphorylation of various hexoses to hexose 6- phosphate. (465 aa)
Hex-t2Hexokinase type 2; Catalyzes the phosphorylation of various hexoses to hexose 6- phosphate. (486 aa)
TpiTriose phosphate isomerase (Tpi) encodes a soluble metabolic protein dimer that functions in glycolysis catalyzing the isomerization between dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, which is essential for efficient ATP production. (348 aa)
Pepck2Phosphoenolpyruvate carboxykinase (GTP) activity; manganese ion binding; GTP binding. (638 aa)
Pepck1Phosphoenolpyruvate carboxykinase 1 (Pepck1) encodes an enzyme that converts oxaloacetate into phosphoenolpyruvate. It catalyzes the first committed step in gluconeogenesis and thus plays an essential role in glucose metabolism. (647 aa)
CG9010Glyceraldehyde-3-phosphate dehydrogenase; Peptidyl-cysteine S-nitrosylase activity; NADP binding; NAD binding; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. It is involved in the biological process described with: oxidation-reduction process; glycolytic process; glucose metabolic process. (343 aa)
Hex-CPhosphotransferase; Hexokinase C (Hex-C) encodes a hexokinase involved in glucose homeostasis. (454 aa)
PfkATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (950 aa)
PCBPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1197 aa)
PgiPhosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis. (558 aa)
Gapdh1Glyceraldehyde 3 phosphate dehydrogenase 1 (Gapdh1) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glycolysis, myoblast fusion and the development of somatic muscle. (332 aa)
G6PGlucose-6-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; glucose 6-phosphate metabolic process. (350 aa)
CG3552Uncharacterized protein, isoform A; GDP-D-glucose phosphorylase activity. It is involved in the biological process described with: glucose metabolic process. (408 aa)
CG7140Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (533 aa)
PhKgammaPhosphorylase kinase gamma (PhKgamma) encodes a protein involved in gastrulation, embryonic mesoderm formation and adult leg musculature development. (560 aa)
PgkPhosphoglycerate kinase (Pgk) encodes an enzyme involved in myoblast fusion; Belongs to the phosphoglycerate kinase family. (415 aa)
CG7322RH57257p; Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; carbonyl reductase (NADPH) activity; L-xylulose reductase (NADP+) activity. It is involved in the biological process described with: xylulose metabolic process; glucose metabolic process. (242 aa)
fbpFructose-1,6-bisphosphatase, isoform F; Fructose 1,6-bisphosphate 1-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; fructose 6-phosphate metabolic process; fructose metabolic process; fructose 1,6-bisphosphate metabolic process; sucrose biosynthetic process; Belongs to the FBPase class 1 family. (343 aa)
GldGlucose dehydrogenase [FAD, quinone] short protein; Glucose dehydrogenase (Gld) encodes a dehydrogenase that belongs to the GMC oxidoreductase family. The product of Gld is essential for the enzymatic modification of the puparium wall that enables the newly developed adult fly to eclose. Gld is also highly expressed in the male and female reproductive tract and its product modulates sperm storage and utilization. (625 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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