STRINGSTRING
CG9961 CG9961 Tpi Tpi Pepck2 Pepck2 Pepck1 Pepck1 PCB PCB Pgi Pgi G6P G6P Pgk Pgk fbp fbp
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CG9961Phosphoglycerate kinase activity; ADP binding; ATP binding. It is involved in the biological process described with: positive regulation of oxidative phosphorylation; gluconeogenesis; glycolytic process. (448 aa)
TpiTriose phosphate isomerase (Tpi) encodes a soluble metabolic protein dimer that functions in glycolysis catalyzing the isomerization between dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, which is essential for efficient ATP production. (348 aa)
Pepck2Phosphoenolpyruvate carboxykinase (GTP) activity; manganese ion binding; GTP binding. (638 aa)
Pepck1Phosphoenolpyruvate carboxykinase 1 (Pepck1) encodes an enzyme that converts oxaloacetate into phosphoenolpyruvate. It catalyzes the first committed step in gluconeogenesis and thus plays an essential role in glucose metabolism. (647 aa)
PCBPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1197 aa)
PgiPhosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis. (558 aa)
G6PGlucose-6-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; glucose 6-phosphate metabolic process. (350 aa)
PgkPhosphoglycerate kinase (Pgk) encodes an enzyme involved in myoblast fusion; Belongs to the phosphoglycerate kinase family. (415 aa)
fbpFructose-1,6-bisphosphatase, isoform F; Fructose 1,6-bisphosphate 1-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; fructose 6-phosphate metabolic process; fructose metabolic process; fructose 1,6-bisphosphate metabolic process; sucrose biosynthetic process; Belongs to the FBPase class 1 family. (343 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (36%) [HD]