node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG9961 | PCB | FBpp0077420 | FBpp0087543 | Phosphoglycerate kinase activity; ADP binding; ATP binding. It is involved in the biological process described with: positive regulation of oxidative phosphorylation; gluconeogenesis; glycolytic process. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.599 |
CG9961 | Pgi | FBpp0077420 | FBpp0087760 | Phosphoglycerate kinase activity; ADP binding; ATP binding. It is involved in the biological process described with: positive regulation of oxidative phosphorylation; gluconeogenesis; glycolytic process. | Phosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis. | 0.977 |
CG9961 | Pgk | FBpp0077420 | FBpp0306279 | Phosphoglycerate kinase activity; ADP binding; ATP binding. It is involved in the biological process described with: positive regulation of oxidative phosphorylation; gluconeogenesis; glycolytic process. | Phosphoglycerate kinase (Pgk) encodes an enzyme involved in myoblast fusion; Belongs to the phosphoglycerate kinase family. | 0.805 |
CG9961 | Tpi | FBpp0077420 | FBpp0084948 | Phosphoglycerate kinase activity; ADP binding; ATP binding. It is involved in the biological process described with: positive regulation of oxidative phosphorylation; gluconeogenesis; glycolytic process. | Triose phosphate isomerase (Tpi) encodes a soluble metabolic protein dimer that functions in glycolysis catalyzing the isomerization between dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, which is essential for efficient ATP production. | 0.998 |
CG9961 | fbp | FBpp0077420 | FBpp0312559 | Phosphoglycerate kinase activity; ADP binding; ATP binding. It is involved in the biological process described with: positive regulation of oxidative phosphorylation; gluconeogenesis; glycolytic process. | Fructose-1,6-bisphosphatase, isoform F; Fructose 1,6-bisphosphate 1-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; fructose 6-phosphate metabolic process; fructose metabolic process; fructose 1,6-bisphosphate metabolic process; sucrose biosynthetic process; Belongs to the FBPase class 1 family. | 0.577 |
G6P | PCB | FBpp0111930 | FBpp0087543 | Glucose-6-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; glucose 6-phosphate metabolic process. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.649 |
G6P | Pepck1 | FBpp0111930 | FBpp0085880 | Glucose-6-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; glucose 6-phosphate metabolic process. | Phosphoenolpyruvate carboxykinase 1 (Pepck1) encodes an enzyme that converts oxaloacetate into phosphoenolpyruvate. It catalyzes the first committed step in gluconeogenesis and thus plays an essential role in glucose metabolism. | 0.936 |
G6P | Pepck2 | FBpp0111930 | FBpp0085878 | Glucose-6-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; glucose 6-phosphate metabolic process. | Phosphoenolpyruvate carboxykinase (GTP) activity; manganese ion binding; GTP binding. | 0.923 |
G6P | Pgi | FBpp0111930 | FBpp0087760 | Glucose-6-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; glucose 6-phosphate metabolic process. | Phosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis. | 0.929 |
G6P | fbp | FBpp0111930 | FBpp0312559 | Glucose-6-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; glucose 6-phosphate metabolic process. | Fructose-1,6-bisphosphatase, isoform F; Fructose 1,6-bisphosphate 1-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; fructose 6-phosphate metabolic process; fructose metabolic process; fructose 1,6-bisphosphate metabolic process; sucrose biosynthetic process; Belongs to the FBPase class 1 family. | 0.598 |
PCB | CG9961 | FBpp0087543 | FBpp0077420 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoglycerate kinase activity; ADP binding; ATP binding. It is involved in the biological process described with: positive regulation of oxidative phosphorylation; gluconeogenesis; glycolytic process. | 0.599 |
PCB | G6P | FBpp0087543 | FBpp0111930 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Glucose-6-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; glucose 6-phosphate metabolic process. | 0.649 |
PCB | Pepck1 | FBpp0087543 | FBpp0085880 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoenolpyruvate carboxykinase 1 (Pepck1) encodes an enzyme that converts oxaloacetate into phosphoenolpyruvate. It catalyzes the first committed step in gluconeogenesis and thus plays an essential role in glucose metabolism. | 0.974 |
PCB | Pepck2 | FBpp0087543 | FBpp0085878 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoenolpyruvate carboxykinase (GTP) activity; manganese ion binding; GTP binding. | 0.971 |
PCB | Pgi | FBpp0087543 | FBpp0087760 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis. | 0.737 |
PCB | Pgk | FBpp0087543 | FBpp0306279 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoglycerate kinase (Pgk) encodes an enzyme involved in myoblast fusion; Belongs to the phosphoglycerate kinase family. | 0.618 |
PCB | Tpi | FBpp0087543 | FBpp0084948 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Triose phosphate isomerase (Tpi) encodes a soluble metabolic protein dimer that functions in glycolysis catalyzing the isomerization between dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, which is essential for efficient ATP production. | 0.733 |
PCB | fbp | FBpp0087543 | FBpp0312559 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Fructose-1,6-bisphosphatase, isoform F; Fructose 1,6-bisphosphate 1-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; fructose 6-phosphate metabolic process; fructose metabolic process; fructose 1,6-bisphosphate metabolic process; sucrose biosynthetic process; Belongs to the FBPase class 1 family. | 0.681 |
Pepck1 | G6P | FBpp0085880 | FBpp0111930 | Phosphoenolpyruvate carboxykinase 1 (Pepck1) encodes an enzyme that converts oxaloacetate into phosphoenolpyruvate. It catalyzes the first committed step in gluconeogenesis and thus plays an essential role in glucose metabolism. | Glucose-6-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; glucose 6-phosphate metabolic process. | 0.936 |
Pepck1 | PCB | FBpp0085880 | FBpp0087543 | Phosphoenolpyruvate carboxykinase 1 (Pepck1) encodes an enzyme that converts oxaloacetate into phosphoenolpyruvate. It catalyzes the first committed step in gluconeogenesis and thus plays an essential role in glucose metabolism. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.974 |