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Dhfr | Dihydrofolate reductase (Dhfr) encodes an NADPH-dependent enzyme used to convert folic acid and dihydrofolate to tetrahydrofolate, which is used as a cofactor for the biosynthesis of purines, thymidylate, and several amino acids. Dhfr product contributes to cell proliferation and cell growth. (182 aa) | ||||
Shmt | Serine hydroxymethyl transferase (Shmt) encodes a conserved pyridoxal phosphate-containing enzyme that converts serine into glycine and N5,N10-methylentetrahydrofolate. This reaction represents a major source for activated C1 units and tetrahydrofolate-mediated C1 metabolism; Belongs to the SHMT family. (537 aa) | ||||
Spat | Serine pyruvate aminotransferase (Spat) encodes an alanine-glyoxylate transaminase involved in glyoxylate catabolism. (394 aa) | ||||
CG10184 | LD34157p; L-allo-threonine aldolase activity. It is involved in the biological process described with: threonine catabolic process; glycine biosynthetic process. (383 aa) |