(9 nodes) Neutral amino acid transmembrane transporter activity network (Drosophila melanogaster)

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	Sfxn1-3	Sideroflexin-1-3; Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria; Belongs to the sideroflexin family. (321 aa)
	NAAT1	Sodium-dependent nutrient amino acid transporter 1; Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine. (641 aa)
	Eaat2	Excitatory amino acid transporter 2 (Eaat2) encodes a transmembrane protein involved in aspartate and taurine transport. (579 aa)
	GlyT	Transporter; It is involved in the biological process described with: regulation of circadian rhythm; glycine import across plasma membrane; neurotransmitter transport; glycine transport; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (1188 aa)
	Balat	Beta-alanine transporter; Beta-alanine transporter required for the uptake of beta- alanine by the glia. Required for the recycling process of the neurotransmitter histamine in photoreceptor neurons of the compound eye and therefore for photoreceptor synaptic transmission. Following histamine release from photoreceptors and its uptake by glia, histamine is conjugated to beta-alanine by e/Ebony to form the inactive metabolite, carcinine. (604 aa)
	VGAT	Vesicular GABA Transporter (VGAT) encodes an essential transporter that is responsible for packaging the neurotransmitter GABA into synaptic vesicles. (549 aa)
	Eaat1	Excitatory amino acid transporter 1 (Eaat1) encodes a transmembrane protein with a glutamate:sodium symporter activity. It is regulated by Notch signalling and contributes to larval locomotion and lifespan. (479 aa)
	Ntl	Transporter; Neurotransmitter transporter-like (Ntl) encodes a glycine transporter of the SLC6 class, closely related to neurotransmitter transporters and other amino acid transporters. Ntl expression is testes-specific and its mutants are male-sterile, producing sperm with a significant reduction in glycylated tubulin; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (590 aa)
	Sfxn2	Sideroflexin-2; Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria; Belongs to the sideroflexin family. (327 aa)

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Eaat1	GlyT	FBpp0079401	FBpp0290385	Excitatory amino acid transporter 1 (Eaat1) encodes a transmembrane protein with a glutamate:sodium symporter activity. It is regulated by Notch signalling and contributes to larval locomotion and lifespan.	Transporter; It is involved in the biological process described with: regulation of circadian rhythm; glycine import across plasma membrane; neurotransmitter transport; glycine transport; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.657
Eaat1	NAAT1	FBpp0079401	FBpp0070763	Excitatory amino acid transporter 1 (Eaat1) encodes a transmembrane protein with a glutamate:sodium symporter activity. It is regulated by Notch signalling and contributes to larval locomotion and lifespan.	Sodium-dependent nutrient amino acid transporter 1; Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.	0.637
Eaat1	VGAT	FBpp0079401	FBpp0086703	Excitatory amino acid transporter 1 (Eaat1) encodes a transmembrane protein with a glutamate:sodium symporter activity. It is regulated by Notch signalling and contributes to larval locomotion and lifespan.	Vesicular GABA Transporter (VGAT) encodes an essential transporter that is responsible for packaging the neurotransmitter GABA into synaptic vesicles.	0.689
Eaat2	GlyT	FBpp0290531	FBpp0290385	Excitatory amino acid transporter 2 (Eaat2) encodes a transmembrane protein involved in aspartate and taurine transport.	Transporter; It is involved in the biological process described with: regulation of circadian rhythm; glycine import across plasma membrane; neurotransmitter transport; glycine transport; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.655
Eaat2	NAAT1	FBpp0290531	FBpp0070763	Excitatory amino acid transporter 2 (Eaat2) encodes a transmembrane protein involved in aspartate and taurine transport.	Sodium-dependent nutrient amino acid transporter 1; Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.	0.564
Eaat2	VGAT	FBpp0290531	FBpp0086703	Excitatory amino acid transporter 2 (Eaat2) encodes a transmembrane protein involved in aspartate and taurine transport.	Vesicular GABA Transporter (VGAT) encodes an essential transporter that is responsible for packaging the neurotransmitter GABA into synaptic vesicles.	0.669
GlyT	Eaat1	FBpp0290385	FBpp0079401	Transporter; It is involved in the biological process described with: regulation of circadian rhythm; glycine import across plasma membrane; neurotransmitter transport; glycine transport; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	Excitatory amino acid transporter 1 (Eaat1) encodes a transmembrane protein with a glutamate:sodium symporter activity. It is regulated by Notch signalling and contributes to larval locomotion and lifespan.	0.657
GlyT	Eaat2	FBpp0290385	FBpp0290531	Transporter; It is involved in the biological process described with: regulation of circadian rhythm; glycine import across plasma membrane; neurotransmitter transport; glycine transport; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	Excitatory amino acid transporter 2 (Eaat2) encodes a transmembrane protein involved in aspartate and taurine transport.	0.655
GlyT	VGAT	FBpp0290385	FBpp0086703	Transporter; It is involved in the biological process described with: regulation of circadian rhythm; glycine import across plasma membrane; neurotransmitter transport; glycine transport; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	Vesicular GABA Transporter (VGAT) encodes an essential transporter that is responsible for packaging the neurotransmitter GABA into synaptic vesicles.	0.694
NAAT1	Eaat1	FBpp0070763	FBpp0079401	Sodium-dependent nutrient amino acid transporter 1; Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.	Excitatory amino acid transporter 1 (Eaat1) encodes a transmembrane protein with a glutamate:sodium symporter activity. It is regulated by Notch signalling and contributes to larval locomotion and lifespan.	0.637
NAAT1	Eaat2	FBpp0070763	FBpp0290531	Sodium-dependent nutrient amino acid transporter 1; Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.	Excitatory amino acid transporter 2 (Eaat2) encodes a transmembrane protein involved in aspartate and taurine transport.	0.564
VGAT	Eaat1	FBpp0086703	FBpp0079401	Vesicular GABA Transporter (VGAT) encodes an essential transporter that is responsible for packaging the neurotransmitter GABA into synaptic vesicles.	Excitatory amino acid transporter 1 (Eaat1) encodes a transmembrane protein with a glutamate:sodium symporter activity. It is regulated by Notch signalling and contributes to larval locomotion and lifespan.	0.689
VGAT	Eaat2	FBpp0086703	FBpp0290531	Vesicular GABA Transporter (VGAT) encodes an essential transporter that is responsible for packaging the neurotransmitter GABA into synaptic vesicles.	Excitatory amino acid transporter 2 (Eaat2) encodes a transmembrane protein involved in aspartate and taurine transport.	0.669
VGAT	GlyT	FBpp0086703	FBpp0290385	Vesicular GABA Transporter (VGAT) encodes an essential transporter that is responsible for packaging the neurotransmitter GABA into synaptic vesicles.	Transporter; It is involved in the biological process described with: regulation of circadian rhythm; glycine import across plasma membrane; neurotransmitter transport; glycine transport; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.694