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ABCB7 ABCB7 Hmt-1 Hmt-1 mfrn mfrn Zip99C Zip99C CG7627 CG7627 CG4562 CG4562 Mvl Mvl Fer2LCH Fer2LCH Fer1HCH Fer1HCH
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ABCB7ATP binding cassette subfamily B member 7 (ABCB7) encodes a transporter that likely dimerizes to form a functional transporter. It may act in the mitochondria to transport substrates necessary for the maturation of ICS proteins, which are involved in iron homeostasis. (743 aa)
Hmt-1Heavy metal tolerance factor 1; It is involved in the biological process described with: heme transport; transmembrane transport; response to cadmium ion. (866 aa)
mfrnMitoferrin; Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly; Belongs to the mitochondrial carrier (TC 2.A.29) family. (379 aa)
Zip99CZinc/iron regulated transporter-related protein 99C (Zip99C) encodes an iron transporter located on the Golgi and endoplasmic reticulum that moves iron from the cytoplasm into the secretory compartments; Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily. (355 aa)
CG7627FI20146p1; ATPase activity; ATP binding; ATPase-coupled transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; wound healing. (1355 aa)
CG4562Uncharacterized protein, isoform E; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. (1408 aa)
MvlMalvolio (Mvl) encodes a member of the SLC11 family of metal ion transporters that transports divalent metal cations, including Mn[2+] and Fe[2+]. Its function has been linked to feeding-related decisions, possibly via modulation of dopaminergic signaling. (639 aa)
Fer2LCHFerritin 2 light chain homologue (Fer2LCH) encodes one of two subunits of the major iron storage complex, the ferritin molecule. In insects, ferritin is assembled from 12 Fer1HCH and 12 Fer2LCH subunits and can be found in the secretory pathway of cells and in hemolymph. The product of Fer2LCH provides iron nucleation sites in the internal cavity of the complex required for iron mineralization and is essential for embryogenesis. (236 aa)
Fer1HCHFerritin 1 heavy chain homologue (Fer1HCH) encodes one of two subunits of the major iron storage complex, the ferritin molecule. In insects, ferritin is assembled from 12 Fer1HCH and 12 Fer2LCH subunits and can be found in the secretory pathway of cells and in hemolymph. The product of Fer1HCH has ferroxidase activity required for iron loading into ferritin and is essential for embryogenesis. (245 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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