node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG7560 | Mthfs | FBpp0075903 | FBpp0111637 | GH04035p; FAD binding; methylenetetrahydrofolate reductase (NAD(P)H) activity. It is involved in the biological process described with: methionine biosynthetic process; tetrahydrofolate interconversion; one-carbon metabolic process; oxidation-reduction process. | 5-formyltetrahydrofolate cyclo-ligase activity. It is involved in the biological process described with: tetrahydrofolate interconversion; folic acid-containing compound biosynthetic process. | 0.411 |
CG7560 | Nmdmc | FBpp0075903 | FBpp0081476 | GH04035p; FAD binding; methylenetetrahydrofolate reductase (NAD(P)H) activity. It is involved in the biological process described with: methionine biosynthetic process; tetrahydrofolate interconversion; one-carbon metabolic process; oxidation-reduction process. | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; May play a role in spermatogenesis. | 0.970 |
CG7560 | Shmt | FBpp0075903 | FBpp0070792 | GH04035p; FAD binding; methylenetetrahydrofolate reductase (NAD(P)H) activity. It is involved in the biological process described with: methionine biosynthetic process; tetrahydrofolate interconversion; one-carbon metabolic process; oxidation-reduction process. | Serine hydroxymethyl transferase (Shmt) encodes a conserved pyridoxal phosphate-containing enzyme that converts serine into glycine and N5,N10-methylentetrahydrofolate. This reaction represents a major source for activated C1 units and tetrahydrofolate-mediated C1 metabolism; Belongs to the SHMT family. | 0.978 |
CG7560 | pug | FBpp0075903 | FBpp0081741 | GH04035p; FAD binding; methylenetetrahydrofolate reductase (NAD(P)H) activity. It is involved in the biological process described with: methionine biosynthetic process; tetrahydrofolate interconversion; one-carbon metabolic process; oxidation-reduction process. | C-1-tetrahydrofolate synthase, cytoplasmic; Pugilist (pug) encodes the trifunctional enzyme methylenetetrahydrofolate dehydrogenase involved in the pigmentation of pteridines and ommochromes; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family. | 0.975 |
Mthfs | CG7560 | FBpp0111637 | FBpp0075903 | 5-formyltetrahydrofolate cyclo-ligase activity. It is involved in the biological process described with: tetrahydrofolate interconversion; folic acid-containing compound biosynthetic process. | GH04035p; FAD binding; methylenetetrahydrofolate reductase (NAD(P)H) activity. It is involved in the biological process described with: methionine biosynthetic process; tetrahydrofolate interconversion; one-carbon metabolic process; oxidation-reduction process. | 0.411 |
Mthfs | Nmdmc | FBpp0111637 | FBpp0081476 | 5-formyltetrahydrofolate cyclo-ligase activity. It is involved in the biological process described with: tetrahydrofolate interconversion; folic acid-containing compound biosynthetic process. | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; May play a role in spermatogenesis. | 0.963 |
Mthfs | Shmt | FBpp0111637 | FBpp0070792 | 5-formyltetrahydrofolate cyclo-ligase activity. It is involved in the biological process described with: tetrahydrofolate interconversion; folic acid-containing compound biosynthetic process. | Serine hydroxymethyl transferase (Shmt) encodes a conserved pyridoxal phosphate-containing enzyme that converts serine into glycine and N5,N10-methylentetrahydrofolate. This reaction represents a major source for activated C1 units and tetrahydrofolate-mediated C1 metabolism; Belongs to the SHMT family. | 0.577 |
Mthfs | pug | FBpp0111637 | FBpp0081741 | 5-formyltetrahydrofolate cyclo-ligase activity. It is involved in the biological process described with: tetrahydrofolate interconversion; folic acid-containing compound biosynthetic process. | C-1-tetrahydrofolate synthase, cytoplasmic; Pugilist (pug) encodes the trifunctional enzyme methylenetetrahydrofolate dehydrogenase involved in the pigmentation of pteridines and ommochromes; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family. | 0.961 |
Nmdmc | CG7560 | FBpp0081476 | FBpp0075903 | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; May play a role in spermatogenesis. | GH04035p; FAD binding; methylenetetrahydrofolate reductase (NAD(P)H) activity. It is involved in the biological process described with: methionine biosynthetic process; tetrahydrofolate interconversion; one-carbon metabolic process; oxidation-reduction process. | 0.970 |
Nmdmc | Mthfs | FBpp0081476 | FBpp0111637 | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; May play a role in spermatogenesis. | 5-formyltetrahydrofolate cyclo-ligase activity. It is involved in the biological process described with: tetrahydrofolate interconversion; folic acid-containing compound biosynthetic process. | 0.963 |
Nmdmc | Shmt | FBpp0081476 | FBpp0070792 | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; May play a role in spermatogenesis. | Serine hydroxymethyl transferase (Shmt) encodes a conserved pyridoxal phosphate-containing enzyme that converts serine into glycine and N5,N10-methylentetrahydrofolate. This reaction represents a major source for activated C1 units and tetrahydrofolate-mediated C1 metabolism; Belongs to the SHMT family. | 0.998 |
Nmdmc | pug | FBpp0081476 | FBpp0081741 | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; May play a role in spermatogenesis. | C-1-tetrahydrofolate synthase, cytoplasmic; Pugilist (pug) encodes the trifunctional enzyme methylenetetrahydrofolate dehydrogenase involved in the pigmentation of pteridines and ommochromes; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family. | 0.980 |
Shmt | CG7560 | FBpp0070792 | FBpp0075903 | Serine hydroxymethyl transferase (Shmt) encodes a conserved pyridoxal phosphate-containing enzyme that converts serine into glycine and N5,N10-methylentetrahydrofolate. This reaction represents a major source for activated C1 units and tetrahydrofolate-mediated C1 metabolism; Belongs to the SHMT family. | GH04035p; FAD binding; methylenetetrahydrofolate reductase (NAD(P)H) activity. It is involved in the biological process described with: methionine biosynthetic process; tetrahydrofolate interconversion; one-carbon metabolic process; oxidation-reduction process. | 0.978 |
Shmt | Mthfs | FBpp0070792 | FBpp0111637 | Serine hydroxymethyl transferase (Shmt) encodes a conserved pyridoxal phosphate-containing enzyme that converts serine into glycine and N5,N10-methylentetrahydrofolate. This reaction represents a major source for activated C1 units and tetrahydrofolate-mediated C1 metabolism; Belongs to the SHMT family. | 5-formyltetrahydrofolate cyclo-ligase activity. It is involved in the biological process described with: tetrahydrofolate interconversion; folic acid-containing compound biosynthetic process. | 0.577 |
Shmt | Nmdmc | FBpp0070792 | FBpp0081476 | Serine hydroxymethyl transferase (Shmt) encodes a conserved pyridoxal phosphate-containing enzyme that converts serine into glycine and N5,N10-methylentetrahydrofolate. This reaction represents a major source for activated C1 units and tetrahydrofolate-mediated C1 metabolism; Belongs to the SHMT family. | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; May play a role in spermatogenesis. | 0.998 |
Shmt | pug | FBpp0070792 | FBpp0081741 | Serine hydroxymethyl transferase (Shmt) encodes a conserved pyridoxal phosphate-containing enzyme that converts serine into glycine and N5,N10-methylentetrahydrofolate. This reaction represents a major source for activated C1 units and tetrahydrofolate-mediated C1 metabolism; Belongs to the SHMT family. | C-1-tetrahydrofolate synthase, cytoplasmic; Pugilist (pug) encodes the trifunctional enzyme methylenetetrahydrofolate dehydrogenase involved in the pigmentation of pteridines and ommochromes; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family. | 0.995 |
pug | CG7560 | FBpp0081741 | FBpp0075903 | C-1-tetrahydrofolate synthase, cytoplasmic; Pugilist (pug) encodes the trifunctional enzyme methylenetetrahydrofolate dehydrogenase involved in the pigmentation of pteridines and ommochromes; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family. | GH04035p; FAD binding; methylenetetrahydrofolate reductase (NAD(P)H) activity. It is involved in the biological process described with: methionine biosynthetic process; tetrahydrofolate interconversion; one-carbon metabolic process; oxidation-reduction process. | 0.975 |
pug | Mthfs | FBpp0081741 | FBpp0111637 | C-1-tetrahydrofolate synthase, cytoplasmic; Pugilist (pug) encodes the trifunctional enzyme methylenetetrahydrofolate dehydrogenase involved in the pigmentation of pteridines and ommochromes; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family. | 5-formyltetrahydrofolate cyclo-ligase activity. It is involved in the biological process described with: tetrahydrofolate interconversion; folic acid-containing compound biosynthetic process. | 0.961 |
pug | Nmdmc | FBpp0081741 | FBpp0081476 | C-1-tetrahydrofolate synthase, cytoplasmic; Pugilist (pug) encodes the trifunctional enzyme methylenetetrahydrofolate dehydrogenase involved in the pigmentation of pteridines and ommochromes; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family. | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; May play a role in spermatogenesis. | 0.980 |
pug | Shmt | FBpp0081741 | FBpp0070792 | C-1-tetrahydrofolate synthase, cytoplasmic; Pugilist (pug) encodes the trifunctional enzyme methylenetetrahydrofolate dehydrogenase involved in the pigmentation of pteridines and ommochromes; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family. | Serine hydroxymethyl transferase (Shmt) encodes a conserved pyridoxal phosphate-containing enzyme that converts serine into glycine and N5,N10-methylentetrahydrofolate. This reaction represents a major source for activated C1 units and tetrahydrofolate-mediated C1 metabolism; Belongs to the SHMT family. | 0.995 |