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Eaat1 Eaat1 CG6927 CG6927 Moe Moe fh fh NtR NtR SERCA SERCA galene galene nAChRbeta1 nAChRbeta1 sesB sesB Grd Grd Ir64a Ir64a CG31935 CG31935 nAChRbeta3 nAChRbeta3 park park Rich Rich Itpr Itpr Nmdar1 Nmdar1 GluRIIA GluRIIA Dref Dref Task7 Task7 HisCl1 HisCl1 CG10864 CG10864 ort ort GluRIID GluRIID KaiR1D KaiR1D nAChRalpha2 nAChRalpha2 nAChRbeta2 nAChRbeta2 boss boss Elk Elk Hsc70-5 Hsc70-5 CG12344 CG12344 CG1688 CG1688 sand sand GluRIIB GluRIIB Sh Sh Lcch3 Lcch3 Ih Ih Pink1 Pink1 GluRIIE GluRIIE clumsy clumsy Ekar Ekar eag eag inaF-C inaF-C inaF-A inaF-A shakB shakB CG34396 CG34396 jus jus qvr qvr Ir75a Ir75a nAChRalpha4 nAChRalpha4 inaF-B inaF-B CG8916 CG8916 inaF-D inaF-D nAChRalpha7 nAChRalpha7 Ir75c Ir75c Rim Rim CG43155 CG43155 Smn Smn NaCP60E NaCP60E nAChRalpha1 nAChRalpha1 Slob Slob para para VGlut VGlut CG42340 CG42340 Galphaq Galphaq Fife Fife SecCl SecCl Rdl Rdl Shab Shab Task6 Task6 pHCl-1 pHCl-1 Ca-alpha1T Ca-alpha1T Grik Grik Irk1 Irk1 GluRIIC GluRIIC Adar Adar Irk2 Irk2 nAChRalpha3 nAChRalpha3 Irk3 Irk3 sei sei Ork1 Ork1 GluClalpha GluClalpha SK SK CG42594 CG42594 ATPsynD ATPsynD Rab6 Rab6 Piezo Piezo pHCl-2 pHCl-2 Pzl Pzl nAChRalpha5 nAChRalpha5 cac cac nAChRalpha6 nAChRalpha6
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proteins of unknown 3D structure
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Eaat1Excitatory amino acid transporter 1 (Eaat1) encodes a transmembrane protein with a glutamate:sodium symporter activity. It is regulated by Notch signalling and contributes to larval locomotion and lifespan. (479 aa)
CG6927LD07278p; Neurotransmitter receptor activity; GABA-A receptor activity; extracellular ligand-gated ion channel activity. It is involved in the biological process described with: chemical synaptic transmission; signal transduction; ion transmembrane transport; regulation of membrane potential; nervous system process. (524 aa)
MoeMoesin/ezrin/radixin homolog 1; Involved in connections of major cytoskeletal structures to the plasma membrane. Together with wgn, involved in control of axon targeting of R8 and R2-R5 photoreceptors, independent of egr. In the nucleus, recruited to sites of active transcription by RNA polymerase II where it has a role in nuclear mRNA export together with the mRNA export factor PCID2 and other messenger ribonucleoprotein (mRNP) particles. (649 aa)
fhFrataxin homolog, mitochondrial; Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+). May be able to store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization. Required for ecdysteroidogenesis in the prothoracic gland which is necessary for larval to pupal transition. Belongs to the frataxin family. (190 aa)
NtRNtR, isoform A; Neurotransmitter receptor activity; extracellular ligand-gated ion channel activity; transmembrane signaling receptor activity. It is involved in the biological process described with: signal transduction; regulation of membrane potential; nervous system process; ion transmembrane transport; chemical synaptic transmission. (585 aa)
SERCACalcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type; Sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) encodes an endoplasmic reticulum (ER) calcium pump with roles in ER calcium homeostasis and lipid storage. (1020 aa)
galeneFI03418p; Potassium channel activity; potassium ion leak channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (729 aa)
nAChRbeta1Acetylcholine receptor subunit beta-like 1; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. (521 aa)
sesBADP,ATP carrier protein; Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane. (312 aa)
GrdGamma-aminobutyric acid receptor alpha-like; GABA, an inhibitory neurotransmitter, mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel. May combine with the ligand-gated ion channel subunit Lcch3 to form cation-selective GABA-gated ion channels. (686 aa)
Ir64aIonotropic receptor 64a (Ir64a) encodes a member of the Ionotropic Receptor (IR) family of variant ionotropic glutamate receptors. It is part of a broad-specificity acid sensor that mediates avoidance behavior. (859 aa)
CG31935Rab3 GTPase-activating protein catalytic subunit; Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily. Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP (By similarity). (916 aa)
nAChRbeta3Nicotinic acetylcholine receptor beta 3 (Dbeta3) subunit; Transmembrane signaling receptor activity; acetylcholine-gated cation-selective channel activity; neurotransmitter receptor activity. (441 aa)
parkParkin (park) encodes an E3 ubiquitin ligase with a key role in protein ubiquitination. It is involved in mitochondrion organization, oxidative stress and locomotion; Belongs to the RBR family. Parkin subfamily. (482 aa)
RichGuanine nucleotide exchange factor subunit Rich; Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the Golgi (By similarity). Plays a role in regulating Rab6-dependent CadN transport in photoreceptor cells which is required for the formation of normal synaptic connections between axons from the inner photoreceptor cells in the eye and postsynaptic cells in the brain medulla layer M6, and for the generation of normal postsynaptic responses. (1429 aa)
ItprInositol 1,4,5,-trisphosphate receptor (Itpr) encodes an intracellular ligand gated calcium channel. It functions downstream of G-protein coupled receptors that activate Gq/PLCbeta signaling and generate inositol tris-phosphate. Itpr depletion affects ecdysone release, response to nutritional stress, lipid metabolism and flight; Belongs to the InsP3 receptor family. (2837 aa)
Nmdar1Glutamate [NMDA] receptor subunit 1; NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. Plays a role in associative learning and in long-term memory consolidation. (997 aa)
GluRIIAGlutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. (907 aa)
DrefDNA replication-related element factor (Dref) encodes a BED finger-type transcription factor that binds to the DRE sequence (TATCGATA). The Dref product is involved in tumor suppressor, TOR, JNK and EGFR signalling pathways. It also plays a role in chromatin organization including insulator function, chromatin remodeling, and telomere maintenance. (709 aa)
Task7TWIK-related acid-sensitive K[+] channel 7 (Task7) encodes an ion channel involved in the transmembrane transport of potassium. (340 aa)
HisCl1Histamine-gated chloride channel subunit 1 (HisCl1) encodes an ion transmembrane transport complex subunit that contributes to thermotaxis and chloride transport; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (426 aa)
CG10864Uncharacterized protein; Potassium ion leak channel activity; potassium channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (389 aa)
ortOra transientless (ort) encodes an ionotropic histamine-gated chloride channel required for vision. It is essential in the first-order interneurons to receive histaminergic inputs from the photoreceptors. In the central brain the product of ort modulates preference and tolerance for high and low temperature; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (485 aa)
GluRIIDGlutamate receptor IID (GluRIID) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. (902 aa)
KaiR1DKainate-type ionotropic glutamate receptor subunit 1D; It is involved in the biological process described with: calcium ion import across plasma membrane; regulation of synaptic activity; synaptic transmission, glutamatergic; positive regulation of neuromuscular synaptic transmission; modulation of chemical synaptic transmission. (853 aa)
nAChRalpha2Acetylcholine receptor subunit alpha-like 2; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. (576 aa)
nAChRbeta2Nicotinic Acetylcholine Receptor beta2 (nAChRbeta2) encodes a subunit of the nicotinic acetylcholine receptor, which is part of the superfamily of ligand-gated ion channels. These channels open to facilitate the passage of cations across synaptic membranes in response to the binding of their native ligand, acetylcholine. Mutations in nAChRbeta2 have been associated with resistance phenotypes to several neonicotinoid insecticides. (519 aa)
bossProtein bride of sevenless; Acts as a ligand for sevenless tyrosine-kinase receptor during eye development. (896 aa)
ElkEag-like K[+] channel, isoform A; Voltage-gated potassium channel activity; voltage-gated cation channel activity. It is involved in the biological process described with: regulation of membrane potential; potassium ion transmembrane transport; potassium ion transport. (1284 aa)
Hsc70-5Heat shock 70 kDa protein cognate 5. (686 aa)
CG12344RH55021p; Chloride channel activity; transmembrane signaling receptor activity; glycine-gated chloride ion channel activity; extracellular ligand-gated ion channel activity; neurotransmitter receptor activity; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (449 aa)
CG1688BcDNA.GH04802; Potassium channel activity; potassium ion leak channel activity. It is involved in the biological process described with: stabilization of membrane potential; potassium ion transmembrane transport; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (918 aa)
sandRE21922p; Potassium ion leak channel activity; potassium channel activity. It is involved in the biological process described with: negative regulation of membrane potential; negative regulation of circadian sleep/wake cycle, sleep; stabilization of membrane potential; potassium ion transmembrane transport; cellular response to dopamine; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (395 aa)
GluRIIBGlutamate receptor IIB (GluRIIB) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. (913 aa)
ShPotassium voltage-gated channel protein Shaker; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Forms rapidly inactivating tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient and may contribute to A- type currents. Plays a role in the regulation of sleep need or efficiency ; Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) s [...] (655 aa)
Lcch3Gamma-aminobutyric acid receptor subunit beta-like; GABA, an inhibitory neurotransmitter, mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel. Combines with the ligand-gated ion channel subunit GRD to form cation-selective GABA-gated ion channels when coexpressed in Xenopus laevis oocytes. (496 aa)
IhI[[h]] channel (Ih) encodes a low-threshold, voltage-gated ion channel. It may influence excitatory postsynaptic potential kinetics and integration. (1327 aa)
Pink1PTEN-induced putative kinase 1 (Pink1) is the ortholog of human PINK1, a gene mutated in autosomal recessive Parkinson's disease. Pink1 encodes a mitochondrially targeted Ser-Thr kinase. It has been linked to a number of cellular functions including altering mitochondrial dynamics, the autophagic degradation of dysfunctional mitochondria, and the proper function of Complex I of the electron transport chain. (721 aa)
GluRIIEGlutamate receptor IIE (GluRIIE) encodes an ion channel subunit involved in calcium ion transport. (897 aa)
clumsyClumsy, isoform B; Glutamate receptor activity; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential; ligand-gated ion channel activity; signaling receptor activity; kainate selective glutamate receptor activity. It is involved in the biological process described with: ion transport; modulation of chemical synaptic transmission; synaptic transmission, glutamatergic; regulation of synaptic activity. (1002 aa)
EkarEye-enriched kainate receptor, isoform B; Eye-enriched kainate receptor (Ekar) encodes an ionotropic receptor that responds to the neurotransmitter glutamate. (899 aa)
eagPotassium voltage-gated channel protein eag; Structural component of a potassium channel. Mediates the potassium permeability of membranes; potassium current is regulated by CaMKII and CASK. Has a role in growth of the perineurial glial layer of the larval peripheral nerve. (1270 aa)
inaF-CGEO11103p1; Channel regulator activity. It is involved in the biological process described with: regulation of membrane potential. (140 aa)
inaF-AInaF-A; Channel regulator activity. It is involved in the biological process described with: regulation of membrane potential. (89 aa)
shakBInnexin shaking-B; Structural component of the gap junctions at electrical synapses in distal and mid-depth levels in the lamina. Isoform Lethal forms voltage sensitive intercellular channels through homotypic interactions; Belongs to the pannexin family. (532 aa)
CG34396Uncharacterized protein, isoform D; Potassium channel activity; potassium ion leak channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (975 aa)
jusJulius seizure (jus) encodes a two-transmembrane domain protein expressed in selected neurons in the optic lobe, subesophageal and thoracic-abdominal ganglia. It is mainly localized to axons and its developmental expression prevents epileptogenesis. (509 aa)
qvrProtein quiver; Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. (158 aa)
Ir75aIonotropic receptor 75a; Odorant receptor for acetic and propionic acid. Functions as part of an olfactory receptor complex including the ionotropic receptor coreceptor Ir8a; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (629 aa)
nAChRalpha4Nicotinic Acetylcholine Receptor alpha4 (nAChRalpha4) encodes a four-pass transmembrane channel that is part of a nicotinic acetycholine receptor complex. It promotes sleep and its expression level peaks when sleep need is high. Its activity is inhibited by the product of qvr. (539 aa)
inaF-BGEO10024p1; inaF-B (inaF-B) encodes a calcium channel regulator involved in response to light and the regulation of photoreceptor cell membrane potential. (81 aa)
CG8916IP12579p; Extracellular ligand-gated ion channel activity; GABA-A receptor activity; chloride channel activity; neurotransmitter receptor activity; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (612 aa)
inaF-DinaF-D (inaF-D) contains four small ORFs named inaF-A, B, C, and D, each of which is spliced to the same down-stream exon. Mutations in inaF-D greatly suppress the expression of the photoreceptor channel protein encoded by trp. (353 aa)
nAChRalpha7Nicotinic Acetylcholine Receptor alpha7 (nAChRalpha7) encodes a subunit of the nicotinic acetylcholine receptor, a pentameric neurotransmitter-gated ion channel. (564 aa)
Ir75cIonotropic glutamate receptor activity; signaling receptor activity; ligand-gated ion channel activity. It is involved in the biological process described with: detection of chemical stimulus involved in sensory perception. (623 aa)
RimRab3 interacting molecule (Rim) encodes a scaffolding protein at the synaptic active zone, with important roles in promoting neurotransmitter release. (2798 aa)
CG43155Uncharacterized protein; Potassium channel activity; potassium ion leak channel activity. It is involved in the biological process described with: stabilization of membrane potential; potassium ion transmembrane transport; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (411 aa)
SmnSurvival motor neuron protein; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm, is required for pre-mRNA splicing in the nucleus and acts as a chaperone that discriminates target and non- target RNAs of Sm proteins. Required for normal expression of spliceosomal snRNAs and for U12 intron splicing. Required in cholinergic neurons, but not in motor neurons, to ensure correct splicing and proper levels of stas mRNA and normal neurotransmitter release by motor neurons. However, Smn is required in motor neurons, but not in cholinergic neurons, for nor [...] (226 aa)
NaCP60ENa channel protein 60E (NaCP60E) encodes a voltage-gated calcium-selective cation channel that likely modulates the stability of neural circuits, particularly under environmental stresses; Belongs to the sodium channel (TC 1.A.1.10) family. NaCP60E subfamily. (2896 aa)
nAChRalpha1Acetylcholine receptor subunit alpha-like 1; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. (597 aa)
SlobSlowpoke-binding protein; Regulator of calcium-activated channel Slo. Increases or decreases the voltage sensitivity of Slo, depending on the absence or presence of 14-3-3-zeta in the complex, respectively. (1347 aa)
paraSodium channel protein para; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. Belongs to the sodium channel (TC 1.A.1.10) family. Para subfamily. (2145 aa)
VGlutVesicular glutamate transporter, isoform A. (632 aa)
CG42340Uncharacterized protein, isoform B; Potassium ion leak channel activity. It is involved in the biological process described with: stabilization of membrane potential; potassium ion transmembrane transport; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (720 aa)
GalphaqG protein alpha q subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Could be the transducin analog, an amplifier and one of the transducers of a visual impulse that performs the coupling between opsin and cGMP-phosphodiesterase. Could mediate a subset of olfactory and gustatory responses. (396 aa)
FifeFife, isoform D; Fife (Fife) encodes a synaptic scaffolding protein that promotes neurotransmitter release and normal motor behavior. (1314 aa)
SecClIP12572p; Glycine-gated chloride ion channel activity; extracellular ligand-gated ion channel activity; GABA-A receptor activity; neurotransmitter receptor activity; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (509 aa)
RdlGamma-aminobutyric acid receptor subunit beta; Resistant to dieldrin (Rdl) encodes a widely-expressed ligand-gated chloride channel which mediates the fast inhibitory effects of GABA. It has been shown to have roles in the circuits underlying visual processing, odor coding, learning and memory, sleep and courtship behavior. (608 aa)
ShabPotassium voltage-gated channel protein Shab; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. (1607 aa)
Task6TWIK-related acid-sensitive K[+] channel 6 (Task6) encodes an ion channel involved in the transmembrane transport of potassium. (408 aa)
pHCl-1pH-sensitive chloride channel 1 (pHCl-1) encodes a protein involved in chloride transmembrane transport; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (978 aa)
Ca-alpha1TCa[2+]-channel protein alpha[[1]] subunit T (Ca-alpha1T) encodes an alpha 1 subunit of a T-type like voltage gated calcium channel. It mediates a low voltage activated transient calcium current in antennal lobe projection neurons and wing motoneurons that is sensitive to amiloride. (3218 aa)
GrikGrik, isoform C; Transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential; glutamate receptor activity; signaling receptor activity; kainate selective glutamate receptor activity; ligand-gated ion channel activity. It is involved in the biological process described with: ion transport; modulation of chemical synaptic transmission; synaptic transmission, glutamatergic; regulation of synaptic activity. (907 aa)
Irk1Inwardly rectifying potassium channel 1 (Irk1) encodes a K[+] channel involved in transepithelial ion transport in the renal tubule and in regulating excitability of the LNv subset of circadian pacemaker neurons. (652 aa)
GluRIICGlutamate receptor IIC (GluRIIC) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. It is required for the synaptic localization of the products of GluRIIA and GluRIIB and for synaptic transmission. (940 aa)
AdarDouble-stranded RNA-specific editase Adar; Has A-to-I RNA editing activity on extended dsRNA: edits RNA- binding protein Rnp4F. A-to-I editing of pre-mRNAs acts predominantly through nervous system targets to affect adult nervous system integrity, function and behavior. Essential for adaptation to environmental stresses, such as oxygen deprivation, and for the prevention of premature neuronal degeneration, through the editing of ion channels as targets. (669 aa)
Irk2Inwardly rectifying potassium channel 2 (Irk2) encodes a protein that is required in transepithelial fluid secretion and potassium transport in the Malpighian tubule. It contributes to wing patterning, through the regulation of release of the product of dpp. (454 aa)
nAChRalpha3Nicotinic Acetylcholine Receptor alpha3 (nAChRalpha3) encodes a subunit of the nicotinic acetylcholine receptor, which is a pentameric neurotransmitter-gated ion channel. (795 aa)
Irk3Inwardly rectifying potassium channel 3 (Irk3) encodes a protein involved in wing disc development. (446 aa)
seiPutative potassium channel subunit homolog; Seizure (sei) encodes a protein involved in sound perception. (855 aa)
Ork1Open rectifier K[+] channel 1 (Ork1) encodes a member of the two pore open rectifier potassium channel gene family. It contributes to the regulation of membrane resting potential. The primary gating mechanism for the product of Ork1 appears to be based on phosphorylation of multiple serine, threonine and tyrosine residues in the large intracellular C-terminal tail. (1019 aa)
GluClalphaGlutamate-gated chloride channel; Glutamate-gated chloride channel subunit. Glutamate binding triggers a rapidly reversible current, while the anti-helmintic drug ivermectin triggers a permanently open channel configuration. (463 aa)
SKSmall conductance calcium-activated potassium channel protein; Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin (By similarity). (1174 aa)
CG42594Uncharacterized protein, isoform C; Potassium channel activity; potassium ion leak channel activity. It is involved in the biological process described with: stabilization of membrane potential; potassium ion transmembrane transport; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (1039 aa)
ATPsynDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (178 aa)
Rab6Ras-related protein Rab6; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Mediates membrane trafficking during egg chamber growth and organization, possibly upstream of exocyst component Sec5. Also during oogenesis, plays a role, together with BicD but independently of Sec5, in the polarization of the oocyte microtubule cytoskeleton, in the localization of oskar mRNA and in the anterodorsal secretion of grk. Required for anterograde opsin transport through the ER-Golgi complex. Plays a role, together with Rich, in regula [...] (208 aa)
PiezoPiezo-type mechanosensitive ion channel component; Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Plays a major role in nociception (response to strong or painful touch) ; Belongs to the PIEZO (TC 1.A.75) family. (2973 aa)
pHCl-2pH-sensitive chloride channel 2 (pHCl-2) encodes a channel involved in chloride transmembrane transport and renal water transport regulation; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (526 aa)
PzlCation channel activity; mechanosensitive ion channel activity. It is involved in the biological process described with: regulation of membrane potential; mechanosensory behavior; cellular response to mechanical stimulus; detection of mechanical stimulus. (2326 aa)
nAChRalpha5Nicotinic Acetylcholine Receptor alpha5 (nAChRalpha5) encodes a subunit of the nicotinic acetylcholine receptor, which is a pentameric neurotransmitter-gated ion channel. (837 aa)
cacVoltage-dependent calcium channel type A subunit alpha-1; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, neurotransmitter release, gene expression, cell motility, cell division and cell death (By similarity). Probably encodes a dihydropyridine- insensitive current. Vital for survival to adulthood. (2110 aa)
nAChRalpha6Nicotinic Acetylcholine Receptor alpha6 (nAChRalpha6) encodes a postsynaptic receptor involved in cation transport, synaptic transmission, muscle homeostasis and sensitivity to insecticides. (523 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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