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| | Nxt1 | NTF2-related export protein; Stimulator of protein export for NES-containing proteins (By similarity). Plays a role in the nuclear export of mRNA. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA (By similarity). In the ovaries, forms a complex with nxf2, Panx and piwi which acts as effectors of cotranscriptional transposon silencing. (133 aa) |
| | egh | Beta-1,4-mannosyltransferase egh; Glycosyltransferase with a proposed role in glycosphingolipid biosynthesis. Neurogenic protein implicated in epithelial development. Critical component of a differential oocyte-follicle cell adhesive system; Belongs to the glycosyltransferase 2 family. (457 aa) |
| | thoc7 | THO complex protein 7; The THO complex is required for cell proliferation and for proper export of heat-shock mRNAs under heat stress. Belongs to the THOC7 family. (288 aa) |
| | sbr | Nuclear RNA export factor 1; Mediates the export of the majority of mRNAs from the nucleus to the cytoplasm. (672 aa) |
| | Dlic | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (493 aa) |
| | e(y)2 | Enhancer of yellow 2 transcription factor; Involved in mRNA export coupled transcription activation by association with both the AMEX and the SAGA complexes. The SAGA complex is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Involved in t [...] (101 aa) |
| | Nup93-1 | Nuclear pore complex protein Nup93-1; Required for nuclear pore complex assembly, maintenance and function. Required for nuclear import of phosphorylated Mad via importin msk. Has no role in classical nuclear localization signal (cNLS)-dependent nuclear import via importin-beta. Together with Nup62 and Nup154, contributes to karyosome morphology and chromatin organization including attachment to the nuclear envelope in oocytes and nurse cells ; Belongs to the nucleoporin interacting component (NIC) family. (823 aa) |
| | CG6961 | LD35981p; mRNA binding; nucleic acid binding. (474 aa) |
| | CG18259 | FI13061p; Nucleic acid binding. (474 aa) |
| | Moe | Moesin/ezrin/radixin homolog 1; Involved in connections of major cytoskeletal structures to the plasma membrane. Together with wgn, involved in control of axon targeting of R8 and R2-R5 photoreceptors, independent of egr. In the nucleus, recruited to sites of active transcription by RNA polymerase II where it has a role in nuclear mRNA export together with the mRNA export factor PCID2 and other messenger ribonucleoprotein (mRNP) particles. (649 aa) |
| | Trs20 | Probable trafficking protein particle complex subunit 2; May play a role in vesicular transport from endoplasmic reticulum to Golgi. Involved in dsRNA uptake. (139 aa) |
| | Arl1 | ADP-ribosylation factor-like protein 1; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. (180 aa) |
| | AGO2 | Protein argonaute-2; Essential for RNA interference (RNAi); double-stranded RNA induces potent and specific gene silencing. RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys or silences messenger RNAs homologous to the silencing trigger; Belongs to the argonaute family. Ago subfamily. (1217 aa) |
| | DCTN1-p150 | Dynactin 1, p150 subunit (DCTN1-p150) encodes the p150 subunit of the dynactin complex. Dynactin is thought to act as a dynein receptor that modulates binding of dynein to cellular cargoes and enhances the processivity of dynein movement. The roles of the product of DCTN1-p150 include oocyte polarity, mitotic cell division, embryonic development, neuronal transport and neurogenesis. (1265 aa) |
| | PCID2 | PCI domain-containing protein 2 homolog; Required for mRNA export together with Moe. Associates with translationally active polysomes. (395 aa) |
| | alphaTub67C | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. (462 aa) |
| | Cog3 | Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport. (905 aa) |
| | Hpr1 | Hpr1 protein; It is involved in the biological process described with: mRNA export from nucleus in response to heat stress; mRNA export from nucleus; regulation of DNA-templated transcription, elongation; signal transduction. (701 aa) |
| | Hel25E | ATP-dependent RNA helicase WM6; Required for mRNA export out of the nucleus. Probable RNA helicase that may regulate entry into mitosis by down-regulating the expression of other genes whose activity may be rate-limiting for entry into mitosis during embryogenesis. Binds to salivary gland chromosomes and modifies position effect variegation. Promotes an open chromatin structure that favors transcription during development by regulating the spread of heterochromatin. (424 aa) |
| | Sem1 | Probable 26S proteasome complex subunit sem1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis. (79 aa) |
| | ninaC | Neither inactivation nor afterpotential protein C; Required for photoreceptor cell function. The ninaC proteins combines putative serine/threonine-protein kinase and myosin activities. Essential for the expression and stability of the rtp protein in the photoreceptors. The rtp/ninaC complex is required for stability of inad and inac and the normal termination of phototransduction in the retina. (1501 aa) |
| | Nup107 | Nuclear pore complex protein Nup107; Plays a role in nuclear pore complex (NPC) assembly and maintenance. Required for nuclear import of Mad. Plays a role in double strand break repair by relocalizing the heterochromatic double strain breaks (DSBs) to the nuclear periphery as part of the homologous recombination (HR) repair process. Regulates cytokinesis during spermatocyte meiosis by maintaining type-B lamin Lam localization to the spindle envelope. Regulates female gonad development and oogenesis. Belongs to the nucleoporin Nup84/Nup107 family. (845 aa) |
| | Nup160 | Nuclear pore complex protein Nup160 homolog; Functions as a component of the nuclear pore complex (NPC). Involved in poly(A)+ RNA transport (By similarity). Required for nuclear import of Mad. May play a role in double strand break DNA repair. Essential for nephrocyte development. (1411 aa) |
| | VhaSFD | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). (542 aa) |
| | nxf4 | Nuclear export factor 4; RNA binding. It is involved in the biological process described with: poly(A)+ mRNA export from nucleus. (301 aa) |
| | Nup214 | Nuclear pore complex protein Nup214; Serves as a docking site in the receptor-mediated import of substrates across the nuclear pore complex including emb, RanGAP and phosphorylated Mad. Protects mbo/Nup88 from proteasomal degradation at the nuclear pore. Together with mbo/Nup88, sequesters emb in the cytoplasm and thereby attenuates nuclear export signal (NES)-mediated nuclear export. Together with mbo/Nup88, required for the nuclear import of the Rel family transcription factors dorsal (dl) and Dorsal-related immunity factor (Dif) and the activation of an immune response. (1711 aa) |
| | Ref1 | RNA and export factor binding protein 1; mRNA binding; nucleic acid binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. (266 aa) |
| | tex | Tex protein; It is involved in the biological process described with: mRNA export from nucleus. (320 aa) |
| | CG8149 | LD31448p; It is involved in the biological process described with: wing disc dorsal/ventral pattern formation; larval lymph gland hemopoiesis. (308 aa) |
| | tomboy20 | GEO10511p1; P-P-bond-hydrolysis-driven protein transmembrane transporter activity; mitochondrion targeting sequence binding. It is involved in the biological process described with: protein targeting to mitochondrion; protein import into mitochondrial matrix; mitochondrial outer membrane translocase complex assembly; tRNA import into mitochondrion. (147 aa) |
| | CG14712 | LD43047p; Structural constituent of nuclear pore; nuclear localization sequence binding. It is involved in the biological process described with: protein import into nucleus; RNA export from nucleus. (1266 aa) |
| | mbo | Nuclear pore complex protein Nup88; Essential component of nuclear pore complex. Required for the anchoring of Nup214 and emb on the nuclear envelope and thereby attenuates nuclear export signal (NES)-mediated nuclear export. Together with Nup214, required for the nuclear import of the Rel family transcription factors dorsal (dl) and Dorsal-related immunity factor (Dif) and the activation of an immune response. (702 aa) |
| | sqd | RNA-binding protein squid; This protein is a component of ribonucleosomes. Could be needed to organize a concentration gradient of a dorsalizing morphogen (Dm) originating in the germinal vesicle. At least one of the isoforms is essential in somatic tissues. (344 aa) |
| | Nup93-2 | Structural constituent of nuclear pore. It is involved in the biological process described with: poly(A)+ mRNA export from nucleus; protein import into nucleus; nuclear pore organization. (796 aa) |
| | Cog2 | Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function. (710 aa) |
| | Mat89Ba | Nucleolar protein 6; RNA binding. It is involved in the biological process described with: tRNA export from nucleus; rRNA processing; Belongs to the NRAP family. (1193 aa) |
| | CG4572 | Serine-type carboxypeptidase activity. It is involved in the biological process described with: dsRNA transport; proteolysis involved in cellular protein catabolic process; Belongs to the peptidase S10 family. (482 aa) |
| | Srp72 | Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (650 aa) |
| | CG5382 | Zinc finger protein-like 1 homolog; Zinc ion binding. It is involved in the biological process described with: dsRNA transport. (299 aa) |
| | AP-2mu | Adaptor Protein complex 2, mu subunit (AP-2mu) encodes a component of the AP-2 adaptor complex, which recruits certain transmembrane proteins into clathrin-coated pits for endocytic internalization. (437 aa) |
| | Nup133 | Nuclear pore complex protein Nup133; Probable component of the nuclear pore complex (NPC) (Probable). Plays a role in NPC assembly and/or maintenance. (1200 aa) |
| | Dcr-1 | Endoribonuclease Dcr-1; Essential for RNA interference (RNAi); double-stranded RNA (dsRNA) induces potent and specific gene silencing. RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys or silences messenger RNAs homologous to the silencing trigger. May carry out the initiation step of RNAi by cleaving dsRNA to produce 22 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs. During embryogenesis, involved in germline fate determination; Belongs to the helicase family. Dicer subfamily. (2249 aa) |
| | Rae1 | Rae1 (Rae1) encodes a nucleoporin member of the WD40-repeat beta propeller protein super family. Biological roles of the pleiotropic Rae1 gene product include poly(A)+ mRNA export, cell cycle regulation, male meiosis control and male germ cell post-meiotic differentiation. (346 aa) |
| | Nup98-96 | Nuclear pore complex protein Nup98-Nup96; Part of the nuclear pore complex (NPC). Required for MAD import as part of the Nup107-160 complex and required for nuclear export of Moe probably via its association with Rae1. Plays a role in nuclear mRNA export. Promotes cell antiviral response by upregulating FoxK-dependent antiviral gene transcription. In germline stem cells, involved in their maintenance and division together with the TGF-Beta and EGFR signaling pathways. In larval lymph glands, has a role in the maintenance of hematopoiesis by regulating Pvr expression. [Nuclear pore comp [...] (1960 aa) |
| | Rab7 | Rab7 (Rab7) encodes a small GTPase that contributes to vesicle trafficking regulation. It is involved in endosome maturation and fusion with lysosomes. (207 aa) |
| | RASSF8 | Ras association domain family member 8 (RASSF8) encodes a member of the N-terminal RASSF protein family. It localises with the product of ASPP at the adherens junctions of epithelial cells where it promotes junction stability by repressing Src activity via C-terminal Src kinase. (607 aa) |
| | Slbp | Histone RNA hairpin-binding protein; Stem-loop binding protein (Slbp) encodes a protein that plays an essential role in 3' end processing of histone pre-mRNAs into mature histone mRNAs by recruiting the product of snRNA:U7 to the pre-mRNA. (276 aa) |
| | Sap-r | Saposin-related, isoform A; Saposin-related (Sap-r) encodes the single protein precursor of several sphingolipid activator proteins (Saposins). Loss of Sap-r leads to the accumulation of sphingolipids in lysosomes, resulting in lysosomal dysfunction, defective lipid homeostasis and neurodegeneration. (953 aa) |
| | Vha16-1 | Vacuolar H[+] ATPase 16kD subunit 1 (Vha16-1) encodes the proteolipid component of V-ATPase, which is a multi-functional channel protein. It contributes to vesicle-membrane fusion, hydrophilic molecule transport and intercellular communication. (159 aa) |
| | Nup75 | Nuclear pore complex protein Nup75; Component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance (By similarity). Required for nuclear import of phosphorylated Mad via importin msk. Has no role in classical nuclear localization signal (cNLS)-dependent nuclear import via importin-beta. Facilitates the interaction between Nup93 and sec13 with msk. (668 aa) |
| | Dcr-2 | Dicer-2, isoform A; Dicer-2 (Dcr-2) encodes a member of the RNase III family of double-stranded RNA-specific endonucleases. It acts in the RNAi pathway by cutting long dsRNA into siRNAs. It helps defend flies against viral infection, particularly RNA viruses. It also processes long, partially double-stranded endogenous transcripts (hairpin RNAs) into endo-siRNAs. (1722 aa) |
| | Nup62 | Nuclear pore glycoprotein p62; Essential component of the nuclear pore complex (By similarity). The N-terminal is probably involved in nucleocytoplasmic transport (By similarity). The C-terminal is involved in protein- protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of Nup62 to the pore complex (By similarity). Binds to transcriptionally active genes. Negatively regulates chromatin attachment to the nuclear envelope, probably by preventing chromatin tethering by Nup154. (394 aa) |
| | Arc1 | Activity-regulated cytoskeleton associated protein 1; Master regulator of synaptic plasticity that self-assembles into virion-like capsids that encapsulate RNAs and mediate intercellular RNA transfer from motorneurons to muscles. Arc1 protein is released from motorneurons in extracellular vesicles that mediate the transfer of Arc1 mRNA into muscle cells, where Arc1 mRNA can undergo activity-dependent translation. Intercellular transfer od Arc1 mRNA is required for synaptic plasticity at the neuromuscular junction. May play a role in energy balance: required for regulation of body fat b [...] (254 aa) |
| | mRpL18 | Mitochondrial ribosomal protein L18; 5S rRNA binding; structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation. (186 aa) |
| | Phax | Phosphorylated adaptor for RNA export, isoform A; RNA binding. It is involved in the biological process described with: snRNA export from nucleus. (453 aa) |
| | DCTN2-p50 | Dynactin 2, p50 subunit (DCTN2-p50) encodes a subunit of the dynactin complex. Together with other members of the dynactin complex, the product of DCTN2-p50 is critical for most functions of the minus end-directed microtubule motor cytoplasmic dynein-1, including oocyte polarity, mRNA localization, centrosome localizations, spindle organization, endocytosis and axonal transport. (380 aa) |
| | Gle1 | Nucleoporin Gle1; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC) (By similarity). (677 aa) |
| | nxf2 | Nuclear RNA export factor 2; May be involved in the export of mRNA from the nucleus to the cytoplasm. In the ovaries, forms a complex with nxf2, piwi and Nxt1 which acts as effectors of cotranscriptional transposon silencing. On recruitment to a target transcript, interacts with single stranded RNA, thereby anchoring the complex via the nascent target transcript to chromatin and allowing Panx to recruit silencing effectors to establishing repressive heterochromatin at transposon loci. Does not affect piRNA biogenesis. The interaction with Panx stabilizes the nuclear protein complex. Do [...] (841 aa) |
| | Bet3 | Trafficking protein particle complex subunit; Blocked early in transport 3 (Bet3) encodes a protein involved in dsRNA transport; Belongs to the TRAPP small subunits family. BET3 subfamily. (178 aa) |
| | Chc | Clathrin heavy chain (Chc) encodes a protein that forms part of the clathrin complex, which is the major component of coated vesicles. (1678 aa) |
| | CG7907 | IP13758p; mRNA binding; RNA cap binding. It is involved in the biological process described with: mRNA transport; mRNA splicing, via spliceosome; mRNA cis splicing, via spliceosome; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. (753 aa) |
| | egl | Egalitarian, isoform B; Egalitarian (egl) encodes an RNA binding protein that links specific mRNAs to the minus end-directed microtubule motor, cytoplasmic dynein-1. (1004 aa) |
| | CG8773 | Metalloaminopeptidase activity; peptide binding; zinc ion binding. It is involved in the biological process described with: dsRNA transport; peptide catabolic process; proteolysis. (994 aa) |
| | Snup | Snurportin-1; Snurportin (Snup) encodes a transport adaptor protein that functions together with the product of msk to carry out nuclear import of small nuclear RNPs. It binds specifically to the 2,2,7-trimethylguanosine cap structure that is present on mature snRNAs. Snup is an essential gene, and the protein shuttles between the cytoplasm and the nucleus. (351 aa) |
| | tho2 | Tho2, isoform B; Tho2 (tho2) encodes a component of the THO complex that plays an essential role in nuclear export of mRNAs. (1642 aa) |
| | SF2 | Splicing factor 2 (SF2) encodes a protein involved in alternative mRNA splicing, RNA export from the nucleus and the regulation of the RNA metabolism. (255 aa) |
| | Nup188 | Nucleoporin 188kDa, isoform C; Structural constituent of nuclear pore. It is involved in the biological process described with: RNA export from nucleus; protein import into nucleus; nuclear pore organization. (1866 aa) |
| | Fmr1 | Synaptic functional regulator FMR1; Polyribosome-associated RNA-binding protein that plays a role in neuronal development and synaptic plasticity through the regulation of protein synthesis of mRNAs. Plays a role as a negative translational regulator of specific mRNAs. Represses translation of the microtubule-associated protein futsch mRNA to regulate microtubule-dependent synaptic growth and function. May also be involved in microRNA (miRNA)-mediated translational suppression as part of the RNA-induced silencing complex (RISC). Required for stability of the central pair of microtubule [...] (729 aa) |
| | Ref2 | RNA and export factor binding protein 2, isoform A; mRNA binding; nucleic acid binding. (220 aa) |
| | Rpb4 | DNA-directed RNA polymerase II subunit Rpb4; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Associates with POLR2G. (139 aa) |
| | BicD | Protein bicaudal D; This protein is essential for differentiation. It may play a role in localizing of Nanos (a maternal determinant) activity in oocytes. During oogenesis, plays a specific role, together with Rab6 but independently of Sec5, in the polarization of the oocyte microtubule cytoskeleton, in oskar mRNA localization and in the anterodorsal secretion of grk. Plays a role in the biogenesis of annulate lamellae containing nuclear pore complex components. (802 aa) |
| | Dbp80 | DEAD-box helicase Dbp80; Dead box protein 80 (Dbp80) encodes a putative ATP-dependent RNA helicase (DEAD box helicase), based on sequence similarity to other Dead box proteins, which are involved in mRNA export from the nucleus. (481 aa) |
| | Mtor | Nucleoprotein TPR; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleoporin-associated regions (NARs) that define transcriptionally active regions of the genome. Associates with extended chromosomal regions that alternate between domains of high density binding with those of lo [...] (2346 aa) |
| | Tom20 | Translocase of outer membrane 20, isoform A; Mitochondrion targeting sequence binding; P-P-bond-hydrolysis-driven protein transmembrane transporter activity. It is involved in the biological process described with: protein targeting to mitochondrion; tRNA import into mitochondrion; mitochondrial outer membrane translocase complex assembly; protein import into mitochondrial matrix. (171 aa) |
| | Dhc64C | Dynein heavy chain 64C (Dhc64C) encodes the heavy chain subunit of the cytoplasmic dynein motor complex. The product of Dhc64C forms a dimer, which binds and hydrolyzes ATP providing the power for movement of dynein. It has an essential function in oocyte polarity, mitotic cell division, embryonic development, and neuronal transport and neurogenesis. (4661 aa) |
| | CG9915 | Uncharacterized protein, isoform B; It is involved in the biological process described with: regulation of mRNA export from nucleus; regulation of histone H3-K36 trimethylation; regulation of mRNA processing. (820 aa) |
| | Nup153 | Nuclear pore complex protein Nup153; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in a Importin alpha/Importin beta receptor-dependent manner. Required for nuclear import of Mad. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleopor [...] (1929 aa) |
| | Nup154 | Nuclear pore complex protein Nup154; Component of the nuclear pore complex. Has a role in the organization of the inner nuclear membrane proteins at the nuclear envelope. In germ cells, plays a role in the nuclear localization of components of the dpp signaling pathways, such as Medea and phosphorylated Mad. Binds to chromatin, and together with Nup62 and Nup93-1, contributes to karyosome morphology and chromatin organization including attachment to the nuclear envelope in oocytes and nurse cells. Has a role in female fertility including egg chamber development; in nurse cells, has a r [...] (1365 aa) |
| | HUWE1 | Uncharacterized protein, isoform H; Ubiquitin-protein transferase activity; ubiquitin protein ligase activity. It is involved in the biological process described with: protein ubiquitination; ubiquitin-dependent protein catabolic process; protein polyubiquitination; dsRNA transport. (5151 aa) |
| | Cbp80 | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference via its interaction with Ars2 and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp80 does not bind directly capped RNAs [...] (800 aa) |
| | Ranbp21 | Ranbp21, isoform A; RNA binding; nuclear export signal receptor activity; Ran GTPase binding. It is involved in the biological process described with: regulation of protein export from nucleus; RNA export from nucleus. (1241 aa) |
| | lt | Vacuolar protein sorting-associated protein 41 homolog; Light (lt) encodes a cellular-protein trafficking protein that forms part of the homotypic fusion and vacuolar protein sorting (HOPS) and class C core vacuole/endosome tethering (CORVET) complexes. It is required for fusion of autophagosomes with lysosomes, endocytic down-regulation of Notch signaling, and eye pigment biogenesis; Belongs to the VPS41 family. (841 aa) |
| | e(y)2b | Enhancer of yellow 2b transcription factor; Testis-specific paralog of the ubiquitously expressed transcription and mRNA export factor e(y)2. Cannot functionally replace e(y)2; Belongs to the ENY2 family. (95 aa) |
| | ncd | Protein claret segregational; Non-claret disjunctional (ncd) encodes a minus-end-directed kinesin microtubule motor protein and the sole member of the kinesin-14 motor family. It is required for spindle assembly in oocytes and chromosome attachment to spindles in early embryos; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. NCD subfamily. (700 aa) |
| | Nxf3 | Nuclear export factor 3, isoform B. (559 aa) |
| | CG8671 | Uncharacterized protein, isoform A; It is involved in the biological process described with: dsRNA transport. (1039 aa) |
| | thoc6 | THO complex subunit 6; The THO complex is required for cell proliferation and for proper export of heat-shock mRNAs under heat stress. Belongs to the WD repeat THOC6 family. (350 aa) |
| | xmas | Protein xmas-2; Xmas (xmas) encodes encodes a hydrophilic protein that is involved in spermatogenesis, oogenesis and embryogenesis. (2079 aa) |
| | CG12782 | WD_REPEATS_REGION domain-containing protein; Ubiquitin binding; RNA binding. It is involved in the biological process described with: RNA export from nucleus; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; mRNA export from nucleus. (336 aa) |
| | Pi3K59F | Phosphatidylinositol 3-kinase catalytic subunit type 3; Phosphotidylinositol 3 kinase 59F (Pi3K59F) encodes a lipid kinase that is required for formation of Phosphatidylinositol 3-phosphate. It functions in a core protein complex that includes the products of Atg6 and Vps15. It is involved in the control of vesicle trafficking, including autophagy, endocytosis and phagocytosis. (949 aa) |
| | thoc5 | THO complex subunit 5; The THO complex is required for cell proliferation and for proper export of heat-shock mRNAs under heat stress. Belongs to the THOC5 family. (616 aa) |
| | Gmer | Probable GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction; Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily. (321 aa) |
