STRINGSTRING
gsb gsb rt rt GluRIIA GluRIIA Rab3-GAP Rab3-GAP KaiR1D KaiR1D GluRIIB GluRIIB Sh Sh ppk11 ppk11 ppk16 ppk16 GluRIIE GluRIIE clumsy clumsy Ekar Ekar Dg Dg CG11155 CG11155 Shab Shab Grik Grik
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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gsbProtein gooseberry; Expressed in segmentally repeating pattern to define the polarity of embryonic segments. (427 aa)
rtProtein O-mannosyltransferase 1; Rotated abdomen (rt) encodes a protein that transfers a mannose to the Ser/Thr residues of the product of Dg, via forming an heterodimer with the product of tw. Its roles include myogenesis, muscle architecture and cell adhesion. (886 aa)
GluRIIAGlutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. (907 aa)
Rab3-GAPRab3 GTPase-activating protein regulatory subunit; Probable regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily. Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase- activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP (By similarity). (1341 aa)
KaiR1DKainate-type ionotropic glutamate receptor subunit 1D; It is involved in the biological process described with: calcium ion import across plasma membrane; regulation of synaptic activity; synaptic transmission, glutamatergic; positive regulation of neuromuscular synaptic transmission; modulation of chemical synaptic transmission. (853 aa)
GluRIIBGlutamate receptor IIB (GluRIIB) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. (913 aa)
ShPotassium voltage-gated channel protein Shaker; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Forms rapidly inactivating tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient and may contribute to A- type currents. Plays a role in the regulation of sleep need or efficiency ; Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) s [...] (655 aa)
ppk11Pickpocket 11 (ppk11) encodes a predicted member of the Degenerin/Epithelial Sodium Channel family. In the larval stage, it is expressed in the terminal organ for salt taste and tracheal cells for liquid clearance. It functions in salt taste in adult flies; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (516 aa)
ppk16Pickpocket 16; Sodium channel activity. It is involved in the biological process described with: regulation of synaptic activity; sodium ion transport; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (531 aa)
GluRIIEGlutamate receptor IIE (GluRIIE) encodes an ion channel subunit involved in calcium ion transport. (897 aa)
clumsyClumsy, isoform B; Glutamate receptor activity; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential; ligand-gated ion channel activity; signaling receptor activity; kainate selective glutamate receptor activity. It is involved in the biological process described with: ion transport; modulation of chemical synaptic transmission; synaptic transmission, glutamatergic; regulation of synaptic activity. (1002 aa)
EkarEye-enriched kainate receptor, isoform B; Eye-enriched kainate receptor (Ekar) encodes an ionotropic receptor that responds to the neurotransmitter glutamate. (899 aa)
DgDystroglycan, isoform D; Dystroglycan (Dg) encodes a major non-integrin extracellular matrix (ECM) receptor that connects the ECM to the actin cytoskeleton. It regulates animal survival and temperature preference, muscle integrity, myotendinous and neuromuscular junction formation and function, nervous system development, axon pathfinding, rhabdomere differentiation, neuronal stem cell division and epithelial polarity. (1262 aa)
CG11155FI01405p; Kainate selective glutamate receptor activity; signaling receptor activity; ligand-gated ion channel activity. It is involved in the biological process described with: ion transport; regulation of synaptic activity. (910 aa)
ShabPotassium voltage-gated channel protein Shab; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. (1607 aa)
GrikGrik, isoform C; Transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential; glutamate receptor activity; signaling receptor activity; kainate selective glutamate receptor activity; ligand-gated ion channel activity. It is involved in the biological process described with: ion transport; modulation of chemical synaptic transmission; synaptic transmission, glutamatergic; regulation of synaptic activity. (907 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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