Your Input: | |
| | His1:CG33822 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | HipHop | HP1-HOAP-interacting protein (HipHop) encodes a protein that interacts with the products of cav and Su(var)205. It is involved in telomere capping. (221 aa) |
| | brk | Putative transcription factor; Brinker (brk) encodes a transcriptional repressor that plays important roles in the development of many tissues, including most imaginal discs, where its expression is negatively regulated by Dpp signaling. (704 aa) |
| | Taf2 | TBP-associated factor 2 (Taf2) encodes a protein that forms part of the multisubunit basal transcription factor TFIID. Together with the product of Taf1, it binds the Initiator and/or the DPE core promoter elements. (1221 aa) |
| | Saf6 | SAGA factor-like TAF6 (Saf6) encodes a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. This complex is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of Saf6 replaces the product of mia within SAGA when the product of mia is restricted to the TFIID transcription complex. Notably, the product of Saf6 is essential for SAGA's co-activator function but does not impact either of its enzymatic activities. (717 aa) |
| | Hat1 | Histone acetyltransferase 1 (Hat1) encodes a B-type histone acetyltransferase that localizes to both the cytoplasm and the nucleus. It is involved in the escort machinery of newly synthesized histones encoded by His3 and His4 to chromatin and acetylates the product of His4 at lysines 5 and 12. It also forms a complex with centromeric histone encoded by cid and is involved in cid chromatin assembly. (405 aa) |
| | Daxx | Daxx-like protein; Transcription regulator. Acts as a histone chaperone that facilitates deposition of histone H3.3. Has a role in chromatin remodeling together with asf1 and XNP. Has role in the transcriptional apoptotic response to oxidative and UV stress. (1659 aa) |
| | Su(var)205 | Heterochromatin protein 1; Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. (206 aa) |
| | Taf11 | TBP-associated factor 11 (Taf11) encodes a protein that forms part of the multisubunit basal transcription factor TFIID. It enhances RNA interference efficiency, organizing the assembly of the RISC loading complex. (196 aa) |
| | Bdp1 | B double prime 1 (Bdp1) encodes a transcription factor involved in snRNA gene transcription. (695 aa) |
| | NC2beta | Protein Dr1; Bifunctional basic transcription factor. Activates transcription of DPE (Downstream Promoter Element) containing promoters while repressing transcription of promoters which contain TATA elements. Together with Chrac-14, promotes nucleosome sliding of ATP-dependent nucelosome remodeling complexes. Belongs to the NC2 beta/DR1 family. (183 aa) |
| | Taf7 | Transcription initiation factor TFIID subunit 7; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. (479 aa) |
| | Pbp95 | PSEA-binding protein 95kD (Pbp95) encodes a protein that functions as one of three subunits of the small nuclear RNA (snRNA) activating protein complex, which binds as a complex to a proximal sequence element A (PSEA) to activate transcription of snRNA genes. (721 aa) |
| | M1BP | Motif 1 Binding Protein (M1BP) encodes a transcription pausing factor. It regulates gene transcription via interaction with the Hox proteins encoded by abd-A and Ubx. It contributes to the development of ovarian follicle cells. (418 aa) |
| | Taf12 | TBP-associated factor 12 (Taf12) encodes a protein that forms part of the multisubunit basal transcription factor TFIID, and it is important for its stability. It forms a histone-like pair with Taf4. Taf12 is also an integral component of the Drosophila SAGA histone acetyltransferase complex. (196 aa) |
| | His4r | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | BigH1 | Histone H1 variant BigH1 (BigH1) encodes a germline linker histone H1 variant that is retained in the early embryo until cellularization. It is required for gametogenesis and to maintain silencing of the zygotic genome during early embryogenesis. (353 aa) |
| | Set | Set (Set) encodes a subunit of the inhibitor of histone acetyltransferase (INHAT) complex, which controls histone acetylation. It is involved in transcriptional regulation, which ultimately controls different processes such as p53-mediated apoptosis and neuronal development. (269 aa) |
| | Pbp45 | PSEA-binding protein 45kD (Pbp45) encodes a protein that functions as one of three subunits of the small nuclear RNA (snRNA) activating protein complex, which binds as a complex to a proximal sequence element A (PSEA) to activate transcription of snRNA genes. (363 aa) |
| | cal1 | Chromosome alignment defect 1 (cal1) encodes a protein that is required for maintenance of the epigenetic marks specifying centromeres. It binds to newly synthesized centromere-specific histone H3 variant encoded by cid and recruits it to the centromere by binding to the centromere protein encoded by Cenp-C. (979 aa) |
| | Brf | Brf, isoform A; Brf (Brf) encodes a transcription factor binding protein involved in transcription mediated by RNA polymerase III. (662 aa) |
| | CG18600 | LD14127p; DNA-directed 5'-3' RNA polymerase activity; DNA binding. It is involved in the biological process described with: transcription elongation from RNA polymerase I promoter; nucleolar large rRNA transcription by RNA polymerase I; RNA polymerase I preinitiation complex assembly. (384 aa) |
| | TfIIA-S | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. Part of a rhi-dependent transcription machinery that enables the generation of piRNA precursors from heterochromatin while maintaining the suppression of transposon-encoded promoters and enhancers. Forms a complex with Moonshiner/CG12721 and Trf2 which recruit transcriptional machinery to heterochromatin to initiate the bidirectional transcription [...] (106 aa) |
| | XNP | Transcriptional regulator ATRX homolog; XNP (XNP) encodes two protein isoforms that participate in the maintenance of heterochromatin and chromosomal stability. They interact with heterochromatin proteins such as those encoded by Su(var)205 and ADD1; Belongs to the SNF2/RAD54 helicase family. (1311 aa) |
| | CG5815 | Protein SPT2 homolog; Histone binding; DNA binding. It is involved in the biological process described with: nucleosome assembly; histone exchange; regulation of chromatin assembly; regulation of transcription, DNA-templated. (581 aa) |
| | spn-D | Spindle D (spn-D) encodes a DNA repair protein required for homologous recombinational DNA repair. It functions in meiotic recombination. (270 aa) |
| | mil | AT14585p; Milkah (mil) encodes a nucleosome assembly factor of the Nap family. It is involved in spermatogenesis, long-term memory formation and male courtship. (283 aa) |
| | spn-A | DNA repair protein Rad51 homolog; Spindle A (spn-A) encodes a protein that forms a filament on single-stranded DNA, does a homology search of double-stranded DNA, and catalyzes strand exchange, swapping the single-strand DNA in and displacing the partner of the complementary strand. (336 aa) |
| | rod | Rough deal (rod) encodes the major subunit of the Rod-Zw10-Zwilch (RZZ) complex. RZZ is an essential component of the outer kinetochore during mitosis. RZZ helps monitor and correct kinetochore-microtubule attachments during prometaphase, and consequently it regulates mitotic progression. (2089 aa) |
| | His1:CG31617 | Histone H1; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. (256 aa) |
| | His2A:CG31618 | Histone H2A; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (124 aa) |
| | His3:CG31613 | Histone H3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa) |
| | His4:CG31611 | Histone binding; DNA binding; protein heterodimerization activity. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG17949 | Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (123 aa) |
| | mei-W68 | Meiotic W68 (mei-W68) encodes a protein thought to form a dimer with the TopoVIA subunit encoded by mei-P22 and is required for the formation of double strand breaks during meiosis. (331 aa) |
| | P32 | CG6459 protein; P32 (P32) encodes an evolutionarily conserved mitochondrial protein that functions in presynaptic calcium signaling and neurotransmitter release as well as chromatin metabolism. (263 aa) |
| | dup | Double parked (dup) encodes an essential protein for the initiation of DNA replication due to its recruitment of the MCM helicase to replication origins. (743 aa) |
| | cid | Histone H3-like centromeric protein cid; Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. (225 aa) |
| | Caf1-105 | Chromatin assembly factor 1, p105 subunit (Caf1-105) encodes one of the three subunits of Drosophila chromatin assembly factor 1 (CAF-1). It binds to histones and contributes to heterochromatin formation and maintenance, chromatin assembly, and developmental signal transduction such the Notch signaling pathway. (747 aa) |
| | Cenp-C | Centromeric protein-C (Cenp-C) encodes an essential centromere protein. It binds to the product of cid and provides a binding site for the Mis12 kinetochore protein complex, which is recruited to the centromere at the start of mitotic and meiotic M phases. It also binds the product of cal1, which is crucial for propagation of the epigenetic mark that specifies centromere identity during progression through the cell division cycle. (1411 aa) |
| | His1:CG33801 | Histone H1; Nucleosomal DNA binding; double-stranded DNA binding; chromatin DNA binding. (256 aa) |
| | His3:CG33803 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33804 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His3:CG33806 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33807 | Histone H1; Nucleosomal DNA binding; double-stranded DNA binding; chromatin DNA binding. (256 aa) |
| | His2A:CG33808 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33809 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33810 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His3:CG33812 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33813 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33814 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33815 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33816 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33817 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33818 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33819 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33820 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33821 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | Taf6 | TBP-associated factor 6 (Taf6) encodes a protein that forms part of the multisubunit basal transcription factor TFIID, and it might be important for its stability. It forms a histone-like pair with the product of e(y)1. It is required during all stages of development, but particularly during imaginal disc development and gametogenesis. (606 aa) |
| | His2A:CG33823 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33824 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33825 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33826 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33827 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33828 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33829 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33830 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33831 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33832 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33833 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33834 | Histone H1; Double-stranded DNA binding; chromatin DNA binding; nucleosomal DNA binding. (256 aa) |
| | His2A:CG33835 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33836 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33837 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33838 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33839 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33840 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33841 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33842 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33843 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33844 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33845 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33846 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33847 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33848 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33849 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | Cdc45 | CDC45L (CDC45L) encodes a protein that contributes to 3'-5' DNA helicase activity of the Cdc45/Mcm2-7/GINS complex. It is involved in chromosome condensation and the regulation of the mitotic G1/S transition. (575 aa) |
| | TfIIA-S-2 | Transcription initiation factor IIA subunit 2-2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity (By similarity); Belongs to the TFIIA subunit 2 family. (107 aa) |
| | CG14441 | Uncharacterized protein, isoform A; Zinc ion binding; nucleic acid binding. (1149 aa) |
| | His2A:CG33850 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33851 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33852 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His3:CG33854 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33855 | Histone H1; Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His3:CG33857 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33858 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His3:CG33860 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33861 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33862 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33863 | Nucleosomal DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His1:CG33864 | Chromatin DNA binding. It is involved in the biological process described with: nucleosome assembly. (256 aa) |
| | His2A:CG33865 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization. (124 aa) |
| | His3:CG33866 | Protein heterodimerization activity; nucleosomal DNA binding. It is involved in the biological process described with: nucleosome assembly. (136 aa) |
| | His2B:CG33868 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33869 | DNA binding; protein heterodimerization activity; histone binding. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33870 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33871 | Histone binding; DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33872 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33873 | DNA binding; protein heterodimerization activity; histone binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33874 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33875 | Histone binding; protein heterodimerization activity; DNA binding. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33876 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33877 | Histone binding; DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33878 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33879 | Histone binding; protein heterodimerization activity; DNA binding. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33880 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33881 | Protein heterodimerization activity; DNA binding; histone binding. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33882 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33883 | Protein heterodimerization activity; DNA binding; histone binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33884 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33885 | Histone binding; DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33886 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33887 | Histone binding; DNA binding; protein heterodimerization activity. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33888 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33889 | Protein heterodimerization activity; DNA binding; histone binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33890 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33891 | Protein heterodimerization activity; DNA binding; histone binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33892 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33893 | DNA binding; protein heterodimerization activity; histone binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33894 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33895 | Histone binding; protein heterodimerization activity; DNA binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33896 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33897 | DNA binding; protein heterodimerization activity; histone binding. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33898 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33899 | Histone binding; protein heterodimerization activity; DNA binding. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33900 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33901 | His4:CG33901 (His4:CG33901) encodes a histone H4 replacement variant that is part of the nucleosome core. It is the predominant histone H4 in non-dividing cells. Its amino acid sequence is identical to the cell-cycle regulated histone encoded by His4. (103 aa) |
| | His2B:CG33902 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33903 | Histone binding; protein heterodimerization activity; DNA binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33904 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33905 | Histone binding; protein heterodimerization activity; DNA binding. It is involved in the biological process described with: DNA-templated transcription, initiation; nucleosome assembly. (103 aa) |
| | His2B:CG33906 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33907 | Histone binding; protein heterodimerization activity; DNA binding. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33908 | Protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | His4:CG33909 | Histone binding; DNA binding; protein heterodimerization activity. It is involved in the biological process described with: nucleosome assembly; DNA-templated transcription, initiation. (103 aa) |
| | His2B:CG33910 | DNA binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin assembly or disassembly. (123 aa) |
| | Chrac-14 | DNA polymerase epsilon subunit 3; Accessory component of the DNA polymerase epsilon complex (By similarity). Participates in DNA repair and in chromosomal DNA replication (By similarity). Histone-like protein which promotes nucleosome sliding of ATP-dependent nucleosome remodeling complexes. Part of the chromatin-accessibility complex (CHRAC) which uses energy/ATP to increase the general accessibility of DNA in chromatin. As an heterodimer with Chrac-16, binds DNA and facilitates nucleosome sliding by Acf. Has a role in DNA damage response by preventing cid mislocalization to chromatin [...] (128 aa) |
| | Df31 | Decondensation factor 31 (Df31) encodes a histone binding protein involved in nucleosome assembly. (183 aa) |
| | Pbp49 | PSEA-binding protein 49kD (Pbp49) encodes a protein that functions as one of three subunits of the small nuclear RNA (snRNA) activating protein complex, which binds as a complex to a proximal sequence element A (PSEA) to activate transcription of snRNA genes. (377 aa) |
| | Tfb5 | Transcription factor B5 (Tfb5) encodes a subunit of the basal transcription and DNA repair factor TFIIH, which operates in transcription and DNA repair. (73 aa) |
| | Taf1 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. (2172 aa) |
| | Nap1 | Nucleosome assembly protein 1 (Nap1) encodes a core histone chaperone involved in histone nuclear transfer and chromatin assembly. (370 aa) |
| | CG8223 | Protein NASP homolog; Histone binding. It is involved in the biological process described with: DNA replication-dependent nucleosome assembly; CENP-A containing nucleosome assembly; Belongs to the NASP family. (492 aa) |
| | Su(var)3-9 | Histone-lysine N-methyltransferase Su(var)3-9; Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting Su(var)205/HP1 to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric regions. Involved in heterochromatic gene silencing including the modification of position-effect-variegation. Belongs to the cl [...] (635 aa) |
| | Spc105R | Spc105-related, isoform B; Spc105-related (Spc105R) encodes an essential component of the kinetochore, to which it is recruited by binding to the Mis12 kinetochore complex. The products of Spc105R and Mis12 recruit the Ndc80 complex, which provides the major microtubule binding activity of the kinetochore. (1960 aa) |
| | CG3708 | Uncharacterized protein; Chromatin binding; histone binding. It is involved in the biological process described with: cell differentiation; nucleosome assembly. (362 aa) |
| | chm | Chameau (chm) encodes a histone acetyl transferase involved in epigenetic mechanisms of transcriptional control and regulation of replication origin activity. Its functions include modulation of JNK activity and gene regulation by Polycomb group genes; Belongs to the MYST (SAS/MOZ) family. (811 aa) |
| | TfIIB | Transcription factor IIB (TfIIB) encodes a basal transcription factor that binds to the TATA box-binding protein. It is required for the initiation of transcription by RNA polymerase II. (315 aa) |
| | His3.3A | Histone H3.3A; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes and is specifically enriched in modifications associated with active chromatin. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular mach [...] (136 aa) |
| | TAF1B | TATA box-binding protein-associated factor RNA polymerase I subunit B; Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment (By similarity); Belongs to the RRN7/TAF1B family. (872 aa) |
| | mam | Neurogenic protein mastermind; Mastermind (mam) encodes a transcriptional coactivator that functions in the Notch signaling pathway. It regulates gene expression by interacting with the intracellular domain of the product of N, which is produced upon receptor activation. (1594 aa) |
| | His3.3B | Histone H3.3B (His3.3B) encodes one of two single copy histone H3 variants. His3.3A and His3.3B transcription is not under control of the cell cycle. His3.3B has a long 3'-UTR (> 1500 nucleotides) and can be processed at different polyadenylation sites which are tissue-specific. (136 aa) |
| | enok | Histone acetyltransferase; Enoki mushroom (enok) encodes a MYST family histone acetyltransferase that acetylates lysine residues on histones, including H3K23, to regulate gene transcription. It contributes to stem cell self-renewal, oogenesis and neural development; Belongs to the MYST (SAS/MOZ) family. (2291 aa) |
| | mars | Mars (mars) encodes a microtubule-associated protein that shuttles between the mitotic spindle and the nucleus. It is required for mitotic spindle attachment to the centrosome; Belongs to the SAPAP family. (921 aa) |
| | mia | Meiosis I arrest (mia) encodes a paralog of the generally expressed TBP-associated factor encoded by Taf6. mia is expressed only in differentiating male germ cells, starting in the spermatocyte stage. Along with four other testis-specific TBP-associated factors, the product of mia is required for full levels of transcript production from multiple genes expressed in primary spermatocytes in preparation for meiotic cell cycle progression and spermatid differentiation. (589 aa) |
| | Caf1-180 | Chromatin assembly factor 1, p180 subunit (Caf1-180) encodes a component of the chromatin assembly factor-1, which couples DNA replication to histone deposition. The product of Caf1-180 is involved in nucleosome organization, DNA endoduplication and double-strand DNA break repair. (1183 aa) |
| | Tbp | TATA binding protein (Tbp) encodes a basal transcription factor required at most RNA Pol I and Pol II-transcribed genes. Traditionally thought to be recruited only to TATA box containing promoters, recent work shows that promoters with very weak TATA box consensus sequences also recruit the product of Tbp as a part of the multisubunit TFIID basal transcription factor or via the SAGA histone acetyltransferase complex. (353 aa) |
| | e(y)1 | Transcription initiation factor TFIID subunit 9; Enhancer of yellow 1 (e(y)1) encodes a TAF9 protein and a main component of the Transcription factor II D (TFIID) complex. TFIID is involved in recruiting the transcription machinery to core promoters and organizing specific enhancer-promoter interactions. (278 aa) |
