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mt:Cyt-b mt:Cyt-b levy levy UQCR-14 UQCR-14 COX6B COX6B UQCR-C2 UQCR-C2 Cyt-c1 Cyt-c1 COX5B COX5B COX5BL COX5BL COX7AL COX7AL COX5A COX5A UQCR-14L UQCR-14L Cyt-c1L Cyt-c1L COX4L COX4L COX6AL COX6AL ox ox mt:CoI mt:CoI mt:CoII mt:CoII CG14077 CG14077 CG42376 CG42376 UQCR-11 UQCR-11 UQCR-Q UQCR-Q COX7A COX7A CG43206 CG43206 cype cype UQCR-6.4 UQCR-6.4 CG34172 CG34172 ND-MLRQ ND-MLRQ COX4 COX4 UQCR-11L UQCR-11L COX8 COX8 RFeSP RFeSP COX7C COX7C CG44296 CG44296 CG31644 CG31644
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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mt:Cyt-bCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (378 aa)
levyLevy, isoform A; Cytochrome-c oxidase activity; enzyme regulator activity. It is involved in the biological process described with: mitochondrial electron transport, cytochrome c to oxygen; determination of adult lifespan; regulation of catalytic activity; aerobic respiration. (109 aa)
UQCR-14Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa)
COX6BCytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (96 aa)
UQCR-C2Endopeptidase activity; metal ion binding; ubiquinol-cytochrome-c reductase activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; protein processing involved in protein targeting to mitochondrion. (440 aa)
Cyt-c1Cytochrome c1, isoform A; Heme binding; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; mitochondrial ATP synthesis coupled proton transport. (307 aa)
COX5BCytochrome-c oxidase activity. It is involved in the biological process described with: mitochondrial electron transport, cytochrome c to oxygen; mitochondrial ATP synthesis coupled proton transport. (120 aa)
COX5BLCytochrome-c oxidase activity. It is involved in the biological process described with: mitochondrial electron transport, cytochrome c to oxygen; mitochondrial ATP synthesis coupled proton transport. (154 aa)
COX7ALCytochrome-c oxidase activity. It is involved in the biological process described with: mitochondrial respirasome assembly; regulation of oxidative phosphorylation; mitochondrial electron transport, cytochrome c to oxygen. (106 aa)
COX5ACytochrome c oxidase subunit 5A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (149 aa)
UQCR-14LCytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa)
Cyt-c1LCytochrome c1-like; Heme binding; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; mitochondrial ATP synthesis coupled proton transport. (344 aa)
COX4LCytochrome-c oxidase activity. It is involved in the biological process described with: mitochondrial electron transport, cytochrome c to oxygen. (176 aa)
COX6ALCytochrome-c oxidase activity; enzyme regulator activity. It is involved in the biological process described with: aerobic respiration; mitochondrial electron transport, cytochrome c to oxygen. (94 aa)
oxCytochrome b-c1 complex subunit 9; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inn [...] (55 aa)
mt:CoICytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (511 aa)
mt:CoIICytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (228 aa)
CG14077IP09469p1; Cytochrome-c oxidase activity; enzyme regulator activity. It is involved in the biological process described with: mitochondrial electron transport, cytochrome c to oxygen; aerobic respiration. (289 aa)
CG42376GH09380p1. (92 aa)
UQCR-11Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (85 aa)
UQCR-QUbiquinol-cytochrome-c reductase activity; ubiquinone binding. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c. (89 aa)
COX7ACytochrome c oxidase subunit 7A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (98 aa)
CG43206Uncharacterized protein; Ubiquinol-cytochrome-c reductase activity. (72 aa)
cypeCyclope (cype) encodes a cytochrome c oxidase subunit VIc homolog acting as an enhancer of dpp pathway phenotypes. It is involved in hair and cell growth and in ommatidia development. (77 aa)
UQCR-6.4Ubiquinol-cytochrome-c reductase activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c. (57 aa)
CG34172HDC00331; Cytochrome-c oxidase activity. It is involved in the biological process described with: mitochondrial respirasome assembly; regulation of oxidative phosphorylation. (62 aa)
ND-MLRQNADH dehydrogenase (Ubiquinone) MLRQ subunit, isoform A; Cytochrome-c oxidase activity; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. (83 aa)
COX4Cytochrome c oxidase subunit 4 (COX4) encodes a subunit of the cytochrome-c oxidase. It is involved in cell proliferation and golgi structural organisation. (182 aa)
UQCR-11LCytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (86 aa)
COX8Cytochrome-c oxidase activity. (68 aa)
RFeSPCytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (230 aa)
COX7CCytochrome c oxidase subunit 7C (COX7C) encodes a negative regulator of neuroblast proliferation. (66 aa)
CG44296Uncharacterized protein; Cytochrome-c oxidase activity. It is involved in the biological process described with: mitochondrial electron transport, cytochrome c to oxygen. (76 aa)
CG31644Uncharacterized protein, isoform C; Cytochrome-c oxidase activity. (90 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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