STRINGSTRING
PIG-Z PIG-Z egh egh CG15651 CG15651 Tmtc3 Tmtc3 PIG-M PIG-M Alg3 Alg3 Alg2 Alg2 PIG-B PIG-B CG6659 CG6659 rt rt CG4341 CG4341 CG11149 CG11149 CG15483 CG15483 Dpm1 Dpm1 Alg12 Alg12 CG5038 CG5038 Alg1 Alg1 Alg9 Alg9 CG9171 CG9171 CG31690 CG31690 CG3253 CG3253 Alg11 Alg11 tw tw PIG-V PIG-V
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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PIG-ZGPI mannosyltransferase 4; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers a fourth mannose to some trimannosyl- GPIs during GPI precursor assembly (By similarity). (696 aa)
eghBeta-1,4-mannosyltransferase egh; Glycosyltransferase with a proposed role in glycosphingolipid biosynthesis. Neurogenic protein implicated in epithelial development. Critical component of a differential oocyte-follicle cell adhesive system; Belongs to the glycosyltransferase 2 family. (457 aa)
CG15651FI03527p; It is involved in the biological process described with: protein O-linked mannosylation. (572 aa)
Tmtc3Protein O-mannosyl-transferase Tmtc3; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. (926 aa)
PIG-MGPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. (466 aa)
Alg3Lethal(2)neighbour of tid protein; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation. (510 aa)
Alg2ALG2, alpha-1,3/1,6-mannosyltransferase; Alpha-1,3-mannosyltransferase activity; GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation in endoplasmic reticulum; oligosaccharide-lipid intermediate biosynthetic process. (424 aa)
PIG-BGPI mannosyltransferase 3; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2- GlcN-acyl-PI during GPI precursor assembly (By similarity). Belongs to the glycosyltransferase 22 family. PIGB subfamily. (561 aa)
CG6659C-mannosyltransferase dpy-19 homolog; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins. (872 aa)
rtProtein O-mannosyltransferase 1; Rotated abdomen (rt) encodes a protein that transfers a mannose to the Ser/Thr residues of the product of Dg, via forming an heterodimer with the product of tw. Its roles include myogenesis, muscle architecture and cell adhesion. (886 aa)
CG4341Protein O-mannosyl-transferase TMTC2; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. (938 aa)
CG11149FI01434p; Glucuronosyltransferase activity. It is involved in the biological process described with: protein O-linked mannosylation. (493 aa)
CG15483Uncharacterized protein; Glucuronosyltransferase activity. It is involved in the biological process described with: protein O-linked mannosylation. (407 aa)
Dpm1Probable dolichol-phosphate mannosyltransferase; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; Belongs to the glycosyltransferase 2 family. (241 aa)
Alg12Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation; Belongs to the glycosyltransferase 22 family. (678 aa)
CG5038Protein O-mannosyl-transferase TMTC4; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. (705 aa)
Alg1ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase; Mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation. (446 aa)
Alg9Mannosyltransferase activity; alpha-1,2-mannosyltransferase activity. It is involved in the biological process described with: protein N-linked glycosylation. (623 aa)
CG9171RE67001p; Glucuronosyltransferase activity. It is involved in the biological process described with: protein O-linked mannosylation. (544 aa)
CG31690Protein O-mannosyl-transferase TMTC1; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. (859 aa)
CG3253GH04269p; Glucuronosyltransferase activity. It is involved in the biological process described with: protein O-linked mannosylation. (389 aa)
Alg11ALG11, alpha-1,2-mannosyltransferase, isoform A; GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity. It is involved in the biological process described with: protein N-linked glycosylation; oligosaccharide-lipid intermediate biosynthetic process. (475 aa)
twProtein O-mannosyl-transferase 2; Twisted (tw) encodes a protein that transfers a mannose to the Ser/Thr residues of dystroglycan, via forming an heterodimer with the product of rt. Its roles include myogenesis, muscle architecture and cell adhesion. (765 aa)
PIG-VGPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly. Required for the GPI-mediated endoplasmic reticulum exit and proper targeting to the cell surface of chp. Required for GPI-mediated membrane attachment of chp, qsm and Cont. Essential for microvillar stability in the rhabdomere; Belongs to the PIGV family. (449 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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