Your Input: | |||||
| tut | Tumorous testis (tut) encodes an RNA-binding protein that forms a complex with the products of bam and bgcn. It is required for the restrained mitotic amplification of germ cells during spermatogenesis. (230 aa) | ||||
| shg | DE-cadherin; Cadherins are calcium-dependent cell adhesion proteins. In connecting cells they preferentially interact with themselves in a homophilic manner; cadherins may thus contribute to the sorting of heterogeneous cell types. During oogenesis, integral component of the guidance mechanisms that regulate the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Functions downstream of the two chemoattractant receptors, Pvr and Egfr, to promote BC adhesion between the leader cells of the migrating cluster and the surroundi [...] (1507 aa) | ||||
| bgcn | Benign gonial cell neoplasm (bgcn) encodes an RNA-binding protein involved in germline stem cell lineage differentiation. It forms a translational repressor complex with the product of bam in ovaries and with the products of bam and tut in testis. (1215 aa) | ||||
| bam | Bag of marbles (bam) encodes a protein involved in gametogenesis that is associated with the fusome, a germ cell-specific organelle. It contributes to the fate determination of germline stem cells, in which bam is negatively regulated by the BMP signaling pathway. (442 aa) | ||||