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ntc | Protein nutcracker; Functions together with PI31 to control non-apoptotic caspase activation during sperm individualization. Positively regulates PI31 stability. (314 aa) | ||||
park | Parkin (park) encodes an E3 ubiquitin ligase with a key role in protein ubiquitination. It is involved in mitochondrion organization, oxidative stress and locomotion; Belongs to the RBR family. Parkin subfamily. (482 aa) | ||||
p38b | P38b MAP kinase (p38b) encodes the serine/threonine kinase that constitutes MAP kinase signaling cascades. It is phosphorylated by MAPK kinases and phosphorylates various substrates that play roles in stress responses, immune responses and differentiation; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. (365 aa) | ||||
p38a | P38a MAP kinase (p38a) encodes a member of the mitogen-activated protein kinases responsive to diverse stresses. In immune response, it activates its downstream component encoded by Atf-2 that in turn regulates Duox expression. (366 aa) | ||||
CG15547 | NDK domain-containing protein; It is involved in the biological process described with: negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway. (390 aa) | ||||
Egm | LP02372p; Enigma (Egm) encodes a mitochondrial oxidoreductase involved in oxidative stress response and lipid homeostasis. (639 aa) | ||||
Vdup1 | Vitamin D[[3]] up-regulated protein 1, isoform A; It is involved in the biological process described with: negative regulation of gene expression; protein transport. (342 aa) | ||||
Fer2 | 48 related 2 (Fer2) encodes a bHLH-transcription factor required for the development of a subset of circadian pacemaker neurons and dopaminergic neurons in the protocerebral anterior medial (PAM) and the protocerebral anterior lateral clusters. It is also required for the survival of the PAM cluster dopaminergic neurons in adulthood. (283 aa) | ||||
Pde8 | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8; Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (By similarity). Involved in the positive regulation of MAP kinase signaling and in inhibiting oxidative stress-induced cell death. (1050 aa) |