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nAChRalpha7 | Nicotinic Acetylcholine Receptor alpha7 (nAChRalpha7) encodes a subunit of the nicotinic acetylcholine receptor, a pentameric neurotransmitter-gated ion channel. (564 aa) | ||||
Grip | Glutamate receptor binding protein (Grip) encodes a protein involved in muscle attachment and synapse organization. (1058 aa) | ||||
Abp1 | Actin binding protein 1 (Abp1) encodes an F-actin-binding protein. It plays important roles in cytoskeletal functions of both Scar/WAVE- and wasp-mediated Arp2/3 complex activation during synapse formation, bristle formation and eye development; Belongs to the ABP1 family. (531 aa) | ||||
boss | Protein bride of sevenless; Acts as a ligand for sevenless tyrosine-kinase receptor during eye development. (896 aa) | ||||
Prosap | Prosap, isoform A; Prosap (Prosap) encodes a member of SH3 and multiple ankyrin repeat domain (SHANK) family of genes that encode synaptic scaffolding proteins. It regulates synaptic growth and development, including the structure of the neuromuscular junction and synapses of the calyx, and olfactory acuity. (1871 aa) | ||||
dlg1 | Disks large 1 tumor suppressor protein; During embryonic development, some isoforms are essential for proper neuronal differentiation and organization. Required for cell polarity; maintenance of apicobasal polarity. Plays a critical role at septate junctions in cellular growth control during larval development. The presence of a guanylate kinase domain suggests involvement in cellular adhesion as well as signal transduction to control cellular proliferation. (1030 aa) | ||||
Spn | Spinophilin, isoform J; Spinophilin (Spn) encodes a scaffold protein protein that regulates the neurexin/neuroligin signalling at the presynaptic active zone. (2148 aa) | ||||
Fmr1 | Synaptic functional regulator FMR1; Polyribosome-associated RNA-binding protein that plays a role in neuronal development and synaptic plasticity through the regulation of protein synthesis of mRNAs. Plays a role as a negative translational regulator of specific mRNAs. Represses translation of the microtubule-associated protein futsch mRNA to regulate microtubule-dependent synaptic growth and function. May also be involved in microRNA (miRNA)-mediated translational suppression as part of the RNA-induced silencing complex (RISC). Required for stability of the central pair of microtubule [...] (729 aa) | ||||
scrib | Protein lap4; Scribble (scrib) encodes a scaffolding protein that is part of the conserved machinery regulating apicobasal polarity. It acts with the products of dlg1 and l(2)gl to distinguish the basolateral domain of epithelial cells and neuroblasts, via reciprocally antagonistic interactions with the aPKC/par-6 complex that impacts vesicle trafficking. The product of scrib also organizes synaptic architecture and is implicated in learning and memory. (2585 aa) | ||||
Cln7 | Cln7, isoform A; It is involved in the biological process described with: transmembrane transport. (546 aa) | ||||
PICK1 | Membrane curvature sensor activity; phospholipid binding; protein kinase C binding; protein domain specific binding. (577 aa) |