STRINGSTRING
CG3909 CG3909 Rtf1 Rtf1 atms atms hyx hyx CG6220 CG6220 tplus3b tplus3b tplus3a tplus3a CG12674 CG12674 Ctr9 Ctr9 CG9899 CG9899
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CG3909WD_REPEATS_REGION domain-containing protein. (331 aa)
Rtf1RNA polymerase-associated protein Rtf1; Plays a role in transcription-coupled histone modification. Required for methylation of 'Lys-4' of histone H3. Plays a role in regulation of transcription. Required for maximal induction of heat- shock genes. Plays a role in Notch signaling in the wing margins. (775 aa)
atmsAntimeros, isoform A; Antimeros (atms) encodes a component of the PAF1 complex (together with the products of Atu, hyx, Rtf1 and Ctr9). The PAF1 complex physically interacts with components of the basal transcription machinery and sequence-specific transcription factors to control histone modifications and pause release. (538 aa)
hyxHyrax, isoform A; Hyrax (hyx) encodes a protein recruited by signaling pathway specific transcriptional regulators such as the products of arm and ci and is important for the output of Wingless and Hedgehog pathways. (538 aa)
CG6220FI06213p; RNA polymerase II complex binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex; histone modification; negative regulation of transcription by RNA polymerase II. (359 aa)
tplus3bPlus3 domain-containing protein; DNA binding; RNA polymerase II C-terminal domain phosphoserine binding. (439 aa)
tplus3aFI11009p; RNA polymerase II C-terminal domain phosphoserine binding; DNA binding. (441 aa)
CG12674IP09436p; Chromatin binding; RNA polymerase II complex binding. It is involved in the biological process described with: transcription elongation from RNA polymerase II promoter; histone modification. (314 aa)
Ctr9Ctr9, isoform A; Ctr9 (Ctr9) encodes a highly conserved member of the polymerase-associated factor 1 complex, which controls a number of transcriptional and epigenetic processes. It is involved in the proliferation and terminal differentiation of the central nervous system. (1150 aa)
CG9899TPR_REGION domain-containing protein; RNA polymerase II complex binding; SH2 domain binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; regulation of histone H3-K4 methylation. (922 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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