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Stam | Signal transducing adaptor molecule (Stam) encodes a component of the ESCRT-0 complex, which mediates multivesicular body formation. It is involved in RTK signaling regulation, tracheal cell migration and endosomal trafficking. (689 aa) | ||||
Gga | Golgi-localized, gamma-adaptin ear containing, ARF binding protein (Gga) encodes a clathrin binding protein involved in post-Golgi vesicle-mediated transport. (660 aa) | ||||
Hrs | Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (760 aa) | ||||
CG3529 | GH05942p; It is involved in the biological process described with: intracellular protein transport. (543 aa) |