node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG5618 | Gad1 | FBpp0077837 | FBpp0073131 | LP10922p; Pyridoxal phosphate binding; glutamate decarboxylase activity. It is involved in the biological process described with: carboxylic acid metabolic process. | Glutamic acid decarboxylase 1 (Gad1) encodes an essential, nervous system-specific glutamic acid decarboxylase, which is the synthetic enzyme for the major inhibitory neurotransmitter gamma-Aminobutyric acid (GABA). It is required for a multitude of physiological functions and adult behaviors dependent on GABA, including sleep, memory, circadian rhythms and egg hatching; Belongs to the group II decarboxylase family. | 0.905 |
CG5618 | b | FBpp0077837 | FBpp0301687 | LP10922p; Pyridoxal phosphate binding; glutamate decarboxylase activity. It is involved in the biological process described with: carboxylic acid metabolic process. | Black (b) encodes an aspartate 1-decarboxylase. Mutations of b result in viable flies with a cuticular melanization phenotype. | 0.908 |
Ddc | Tdc2 | FBpp0080710 | FBpp0085475 | Aromatic-L-amino-acid decarboxylase; Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Variation in the synthesis of bioamines may be a factor contributing to natural variation in life span. Belongs to the group II decarboxylase family. | Tyrosine decarboxylase activity; carboxy-lyase activity; pyridoxal phosphate binding. It is involved in the biological process described with: oviposition; locomotor rhythm; behavioral response to cocaine; cellular amino acid metabolic process; locomotory behavior. | 0.907 |
Ddc | amd | FBpp0080710 | FBpp0080698 | Aromatic-L-amino-acid decarboxylase; Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Variation in the synthesis of bioamines may be a factor contributing to natural variation in life span. Belongs to the group II decarboxylase family. | 3,4-dihydroxyphenylacetaldehyde synthase; Catalyzes both the decarboxylation and deamination of L-dopa to 3,4-dihydroxylphenylacetaldehyde (DHPAA). Probably responsible for the protein cross-linking during the development of flexible cuticles. Participates in catecholamine catabolism. | 0.906 |
Gad1 | CG5618 | FBpp0073131 | FBpp0077837 | Glutamic acid decarboxylase 1 (Gad1) encodes an essential, nervous system-specific glutamic acid decarboxylase, which is the synthetic enzyme for the major inhibitory neurotransmitter gamma-Aminobutyric acid (GABA). It is required for a multitude of physiological functions and adult behaviors dependent on GABA, including sleep, memory, circadian rhythms and egg hatching; Belongs to the group II decarboxylase family. | LP10922p; Pyridoxal phosphate binding; glutamate decarboxylase activity. It is involved in the biological process described with: carboxylic acid metabolic process. | 0.905 |
Gad1 | Tdc2 | FBpp0073131 | FBpp0085475 | Glutamic acid decarboxylase 1 (Gad1) encodes an essential, nervous system-specific glutamic acid decarboxylase, which is the synthetic enzyme for the major inhibitory neurotransmitter gamma-Aminobutyric acid (GABA). It is required for a multitude of physiological functions and adult behaviors dependent on GABA, including sleep, memory, circadian rhythms and egg hatching; Belongs to the group II decarboxylase family. | Tyrosine decarboxylase activity; carboxy-lyase activity; pyridoxal phosphate binding. It is involved in the biological process described with: oviposition; locomotor rhythm; behavioral response to cocaine; cellular amino acid metabolic process; locomotory behavior. | 0.477 |
Gad1 | b | FBpp0073131 | FBpp0301687 | Glutamic acid decarboxylase 1 (Gad1) encodes an essential, nervous system-specific glutamic acid decarboxylase, which is the synthetic enzyme for the major inhibitory neurotransmitter gamma-Aminobutyric acid (GABA). It is required for a multitude of physiological functions and adult behaviors dependent on GABA, including sleep, memory, circadian rhythms and egg hatching; Belongs to the group II decarboxylase family. | Black (b) encodes an aspartate 1-decarboxylase. Mutations of b result in viable flies with a cuticular melanization phenotype. | 0.911 |
Tdc1 | Tdc2 | FBpp0085476 | FBpp0085475 | Tyrosine decarboxylase 1 (Tdc1) encodes a protein involved in behavioral response to ethanol. | Tyrosine decarboxylase activity; carboxy-lyase activity; pyridoxal phosphate binding. It is involved in the biological process described with: oviposition; locomotor rhythm; behavioral response to cocaine; cellular amino acid metabolic process; locomotory behavior. | 0.474 |
Tdc2 | Ddc | FBpp0085475 | FBpp0080710 | Tyrosine decarboxylase activity; carboxy-lyase activity; pyridoxal phosphate binding. It is involved in the biological process described with: oviposition; locomotor rhythm; behavioral response to cocaine; cellular amino acid metabolic process; locomotory behavior. | Aromatic-L-amino-acid decarboxylase; Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Variation in the synthesis of bioamines may be a factor contributing to natural variation in life span. Belongs to the group II decarboxylase family. | 0.907 |
Tdc2 | Gad1 | FBpp0085475 | FBpp0073131 | Tyrosine decarboxylase activity; carboxy-lyase activity; pyridoxal phosphate binding. It is involved in the biological process described with: oviposition; locomotor rhythm; behavioral response to cocaine; cellular amino acid metabolic process; locomotory behavior. | Glutamic acid decarboxylase 1 (Gad1) encodes an essential, nervous system-specific glutamic acid decarboxylase, which is the synthetic enzyme for the major inhibitory neurotransmitter gamma-Aminobutyric acid (GABA). It is required for a multitude of physiological functions and adult behaviors dependent on GABA, including sleep, memory, circadian rhythms and egg hatching; Belongs to the group II decarboxylase family. | 0.477 |
Tdc2 | Tdc1 | FBpp0085475 | FBpp0085476 | Tyrosine decarboxylase activity; carboxy-lyase activity; pyridoxal phosphate binding. It is involved in the biological process described with: oviposition; locomotor rhythm; behavioral response to cocaine; cellular amino acid metabolic process; locomotory behavior. | Tyrosine decarboxylase 1 (Tdc1) encodes a protein involved in behavioral response to ethanol. | 0.474 |
amd | Ddc | FBpp0080698 | FBpp0080710 | 3,4-dihydroxyphenylacetaldehyde synthase; Catalyzes both the decarboxylation and deamination of L-dopa to 3,4-dihydroxylphenylacetaldehyde (DHPAA). Probably responsible for the protein cross-linking during the development of flexible cuticles. Participates in catecholamine catabolism. | Aromatic-L-amino-acid decarboxylase; Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Variation in the synthesis of bioamines may be a factor contributing to natural variation in life span. Belongs to the group II decarboxylase family. | 0.906 |
b | CG5618 | FBpp0301687 | FBpp0077837 | Black (b) encodes an aspartate 1-decarboxylase. Mutations of b result in viable flies with a cuticular melanization phenotype. | LP10922p; Pyridoxal phosphate binding; glutamate decarboxylase activity. It is involved in the biological process described with: carboxylic acid metabolic process. | 0.908 |
b | Gad1 | FBpp0301687 | FBpp0073131 | Black (b) encodes an aspartate 1-decarboxylase. Mutations of b result in viable flies with a cuticular melanization phenotype. | Glutamic acid decarboxylase 1 (Gad1) encodes an essential, nervous system-specific glutamic acid decarboxylase, which is the synthetic enzyme for the major inhibitory neurotransmitter gamma-Aminobutyric acid (GABA). It is required for a multitude of physiological functions and adult behaviors dependent on GABA, including sleep, memory, circadian rhythms and egg hatching; Belongs to the group II decarboxylase family. | 0.911 |