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| | pont | RuvB-like helicase 1; Acts as a transcriptional coactivator in Wg signaling caused by altered arm signaling. Pont and rept interfere antagonistically with nuclear arm signaling function, and are required to enhance or reduce arm activity, respectively. Also an essential cofactor for the normal function of Myc; required for cellular proliferation and growth. (456 aa) |
| | Sur | ATP-binding cassette sub-family C member Sur; May function as regulatory subunit of ATP-sensitive potassium channels (KATP) and form KATP channels with a member of the ATP- sensitive inward rectifier potassium channel family (By similarity). May also have channel activity by itself (in vitro). May protect the heart during hypoxia. May protect against heart failure under conditions of tachycardic stress. (2223 aa) |
| | kl-5 | Male fertility factor kl5; ATP binding; microtubule motor activity. It is involved in the biological process described with: microtubule-based movement. (4559 aa) |
| | kl-3 | Male fertility factor kl3 (kl-3) encodes a dynein heavy chain that is a component of a microtubule motor complex. This motor activity is essential only for spermatogenesis. Lack of kl-3 results in loss of the axonemal out dynein arms in the spermatid tail. (4593 aa) |
| | kl-2 | Male fertility factor kl2; ATP binding; ATPase activity; dynein intermediate chain binding; dynein light intermediate chain binding; ATP-dependent microtubule motor activity, minus-end-directed. It is involved in the biological process described with: cilium movement; microtubule-based movement. (4459 aa) |
| | Rpt4R | Regulatory particle triple-A ATPase 4-related, isoform A; Proteasome-activating ATPase activity; ATP binding; ATPase activity. It is involved in the biological process described with: ubiquitin-dependent ERAD pathway; positive regulation of RNA polymerase II transcription preinitiation complex assembly; proteasome-mediated ubiquitin-dependent protein catabolic process; Belongs to the AAA ATPase family. (398 aa) |
| | Rpt3 | Regulatory particle triple-A ATPase 3, isoform A; Proteasome-activating ATPase activity; ATPase activity; ATP binding. It is involved in the biological process described with: positive regulation of RNA polymerase II transcription preinitiation complex assembly; proteasome-mediated ubiquitin-dependent protein catabolic process; protein catabolic process; Belongs to the AAA ATPase family. (413 aa) |
| | Rpt2 | 26S proteasome regulatory subunit 4; Regulatory particle triple-A ATPase 2 (Rpt2) encodes one of six ATPases that form the base of the regulatory 19S cap of the proteasome. The Rpt2 product is involved in the recognition of specific substrates destined for degradation, such as those involved in Notch signalling pathway. (439 aa) |
| | osy | RE14039p; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport. (777 aa) |
| | dpa | DNA replication licensing factor MCM4; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (866 aa) |
| | Spg7 | Paraplegin, isoform A; Metallopeptidase activity; metalloendopeptidase activity; zinc ion binding; ATPase activity; ATP binding. It is involved in the biological process described with: mitochondrion organization; proteolysis. (819 aa) |
| | CG5853 | FI22810p1; ATPase activity; ATP binding; ATPase-coupled transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (689 aa) |
| | RfC38 | Replication factor C 38kD subunit, isoform A; DNA clamp loader activity. It is involved in the biological process described with: DNA-dependent DNA replication; sister chromatid cohesion; DNA repair; leading strand elongation. (356 aa) |
| | Nsf2 | Vesicle-fusing ATPase 2; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity). (752 aa) |
| | CG9492 | Uncharacterized protein, isoform G; Dynein intermediate chain binding; ATP-dependent microtubule motor activity, minus-end-directed; ATP binding; dynein light intermediate chain binding. It is involved in the biological process described with: cilium movement; outer dynein arm assembly; microtubule-based movement; sensory perception of sound. (4724 aa) |
| | ClpX | Uncharacterized protein, isoform C; ATP binding; ATPase activity; unfolded protein binding. It is involved in the biological process described with: protein catabolic process; proteolysis; proteolysis involved in cellular protein catabolic process; regulation of mitochondrial gene expression; protein folding. (679 aa) |
| | CG1703 | LD04461p; ATP binding; ATPase activity. (901 aa) |
| | nmd | No mitochondrial derivative, isoform A; ATP binding. It is involved in the biological process described with: wing disc dorsal/ventral pattern formation; spermatid development; Belongs to the AAA ATPase family. (369 aa) |
| | CG34120 | Uncharacterized protein, isoform E; Lipid transporter activity; ATPase activity; ATP binding; ATPase-coupled transmembrane transporter activity. It is involved in the biological process described with: lipid transport; transmembrane transport. (1998 aa) |
| | Vps4 | Vacuolar protein sorting 4 (Vps4) encodes an AAA family ATPase. It catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes. It functions in endosomal sorting of cargo into the multivesicular body for lysosomal degradation, abscission during cell division, virus release and nuclear envelope membrane sealing after cell division. (442 aa) |
| | E23 | Early gene at 23, isoform C; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity. It is involved in the biological process described with: regulation of circadian rhythm; transmembrane transport. (1017 aa) |
| | CG8908 | Uncharacterized protein; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity; lipid transporter activity. It is involved in the biological process described with: lipid transport; transmembrane transport. (1626 aa) |
| | Pex6 | Peroxin 6, isoform D; ATP binding; ATPase activity. It is involved in the biological process described with: peroxisome organization; protein import into peroxisome matrix; protein targeting to peroxisome. (899 aa) |
| | pch2 | Pachytene checkpoint 2 (pch2) encodes a protein involved in a checkpoint pathway that monitors the synaptonemal complex assembly and recombination during female meiosis; Belongs to the AAA ATPase family. (421 aa) |
| | Dhc93AB | Dynein heavy chain at 93AB (Dhc93AB) encodes a motor protein involved in hearing. (4496 aa) |
| | CG31213 | Uncharacterized protein, isoform B; Lipid transporter activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport; lipid transport. (1809 aa) |
| | Pmp70 | Peroxisomal membrane protein 70 kDa, isoform A; Protein homodimerization activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: long-chain fatty acid import into peroxisome. (665 aa) |
| | c12.2 | C12.2, isoform B; ATPase activity; ATP binding. (1403 aa) |
| | Kat60 | Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (605 aa) |
| | CG31689 | Uncharacterized protein, isoform H; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport. (624 aa) |
| | ATPsynbeta | ATP synthase subunit beta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] (511 aa) |
| | Dhc64C | Dynein heavy chain 64C (Dhc64C) encodes the heavy chain subunit of the cytoplasmic dynein motor complex. The product of Dhc64C forms a dimer, which binds and hydrolyzes ATP providing the power for movement of dynein. It has an essential function in oocyte polarity, mitotic cell division, embryonic development, and neuronal transport and neurogenesis. (4661 aa) |
| | CG1494 | Uncharacterized protein, isoform B; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding; lipid transporter activity. It is involved in the biological process described with: transmembrane transport; lipid transport. (1695 aa) |
| | Fign | Fidgetin-like protein 1; ATP binding; magnesium ion binding; ATPase activity; microtubule-severing ATPase activity; hydrolase activity. (523 aa) |
| | CG4562 | Uncharacterized protein, isoform E; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. (1408 aa) |
| | CG5776 | LD25466p; ATP binding; ATPase activity. (799 aa) |
| | sick | Sickie (sick) encodes a cytoskeletal protein that positively regulates F-actin-mediated axonal growth by relaying the non-canonical RacGTPase-Slingshot-Cofilin pathway. It also mediates immune deficiency signaling pathway, which activates the product of Rel; Belongs to the Nav/unc-53 family. (2707 aa) |
| | CG31792 | Uncharacterized protein, isoform B; ATPase activity; ATP binding; ATPase-coupled transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (1323 aa) |
| | CG43672 | Uncharacterized protein. (1609 aa) |
| | CG13185 | Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5526 aa) |
| | CG42816 | Uncharacterized protein; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding; lipid transporter activity. It is involved in the biological process described with: lipid transport; transmembrane transport. (1459 aa) |
| | CG7627 | FI20146p1; ATPase activity; ATP binding; ATPase-coupled transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; wound healing. (1355 aa) |
| | ABCA | ATP binding cassette subfamily A, isoform B; ATPase activity; ATP binding; ATPase-coupled transmembrane transporter activity; lipid transporter activity. It is involved in the biological process described with: lipid transport; transmembrane transport. (1714 aa) |
| | CG9270 | Uncharacterized protein; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport. (1292 aa) |
| | Rpt4 | Regulatory particle triple-A ATPase 4 (Rpt4) encodes the 19S proteasomal ATPase, which is a component of the 26S proteosome complex. It localizes to the nucleolus and participates in regulating rRNA transcription. It physically interacts with the tumor suppressor encoded by BHD. (397 aa) |
| | YME1L | ATP-dependent zinc metalloprotease YME1L; ATP-dependent metalloprotease that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial intermembrane region. Plays an important role in regulating mitochondrial morphology and function by cleaving Opa1, giving rise to a form of Opa1 that promotes maintenance of normal mitochondrial structure and mitochondrial protein metabolism. Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria fr [...] (740 aa) |
| | Dhc36C | Dynein heavy chain at 36C (Dhc36C) encodes a motor protein involved in hearing. (4024 aa) |
| | Dhc62B | Dynein heavy chain at 62B (Dhc62B) encodes a motor protein involved in retrograde axonal transport. (3964 aa) |
| | l(2)03659 | Probable multidrug resistance-associated protein lethal(2)03659; Vital for development. (1374 aa) |
| | Mrp4 | Multidrug resistance protein 4 (Mrp4) encodes a member of the MRP/ABCC subfamily of ATP-binding cassette (ABC) transporters. It is involved in the response to oxidative stress and hypoxia. (1316 aa) |
| | Rpt3R | Regulatory particle triple-A ATPase 3-related, isoform C; ATPase activity; ATP binding; proteasome-activating ATPase activity. It is involved in the biological process described with: positive regulation of RNA polymerase II transcription preinitiation complex assembly; proteasome-mediated ubiquitin-dependent protein catabolic process; Belongs to the AAA ATPase family. (405 aa) |
| | Dhc98D | Dynein heavy chain at 89D, isoform B; ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding; ATP binding; dynein light intermediate chain binding. It is involved in the biological process described with: microtubule-based movement; cilium movement. (5080 aa) |
| | CG1801 | Uncharacterized protein; Lipid transporter activity; ATPase activity; ATP binding; ATPase-coupled transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; lipid transport. (1655 aa) |
| | kat-60L1 | Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (673 aa) |
| | Dnah3 | Dynein, axonemal, heavy chain 3 (Dnah3) encodes a motor protein involved in hearing and sperm competition. (4385 aa) |
| | btv | Beethoven (btv) encodes the minor cytoplasmic dynein heavy chain, which is the retrograde motor for intraflagellar transport. It is required for the proper assembly of the sensory cilia in chordotonal organs. It contributes to hearing and other chordotonal-dependent functions such as larval locomotion. (4236 aa) |
| | Lon | Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner. Regulates mitochondrial DNA (mtDNA) copy number and transcription by [...] (1024 aa) |
| | CG11898 | Uncharacterized protein; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity. It is involved in the biological process described with: transmembrane transport. (1320 aa) |
| | TER94 | Transitional endoplasmic reticulum ATPase TER94; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Involved in the ubiquitin-proteasome system. Important for oskar mRNA localization and/ [...] (826 aa) |
| | Atet | ABC transporter expressed in trachea (Atet) encodes a protein that is involved in transmembrane transport. (832 aa) |
| | Eato | Engulfment ABC transporter in the ovary, isoform B; Lipid transporter activity; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity. It is involved in the biological process described with: lipid transport; transmembrane transport. (1597 aa) |
| | Gnf1 | Replication factor C subunit 1; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds to the primer-template junction (By similarity). (1008 aa) |
| | smid | Smallminded, isoform A; Preribosome binding; ATPase activity; ATP binding. It is involved in the biological process described with: positive regulation of telomerase activity; ribosome biogenesis. (944 aa) |
| | CG3164 | Uncharacterized protein, isoform A; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport. (699 aa) |
| | MRP | Multidrug-Resistance like protein 1, isoform A; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase-coupled inorganic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; anion transmembrane transport. (1549 aa) |
| | CG5789 | FI20190p1; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. (1402 aa) |
| | ABCD | ATP-binding cassette sub-family D member; Plays a role in the transport of free very-long-chain fatty acids (VLCFAs) as well as their CoA-esters across the peroxisomal membrane by acting as an ATP-specific binding subunit releasing ADP after ATP hydrolysis. Thus, plays a role in regulation of VLCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation, mitochondrial function and microsomal fatty acid elongation; Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily. (730 aa) |
| | Orc1 | Origin recognition complex subunit 1 (Orc1) encodes the largest subunit of the origin recognition complex (ORC), which is essential for the initiation of DNA replication in eukaryotic cells. The ATPase activity of the product of Orc1 is critical for the formation and function of the pre-replicative complex. The regulated degradation of the product of Orc1 by ubiquitin-mediated proteolysis after initiation of DNA replication helps to prevent re-replication. (924 aa) |
| | Rpt1 | 26S proteasome regulatory complex subunit p48B; Regulatory particle triple-A ATPase 1 (Rpt1) encodes an AAA-type ATPase protein that forms part of the heterohexameric ATPase ring of the regulatory complex of the 26S proteasome. (433 aa) |
| | Mdr49 | Multidrug resistance protein homolog 49; Multi drug resistance 49 (Mdr49) encodes drug transmembrane transporter that belongs to the ABCB transporter subfamily and contributes to insecticide resistance. (1302 aa) |
| | Mdr50 | Multi drug resistance 50; Efflux transmembrane transporter activity; ATPase-coupled xenobiotic transmembrane transporter activity; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: response to insecticide; response to toxic substance; xenobiotic transport; transmembrane transport; renal tubular secretion. (1313 aa) |
| | Rpt6R | Regulatory particle triple-A ATPase 6-related; Hydrolase activity; TBP-class protein binding; ATP binding; ATPase activity. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; positive regulation of RNA polymerase II transcription preinitiation complex assembly; modulation of chemical synaptic transmission; Belongs to the AAA ATPase family. (399 aa) |
| | spn-A | DNA repair protein Rad51 homolog; Spindle A (spn-A) encodes a protein that forms a filament on single-stranded DNA, does a homology search of double-stranded DNA, and catalyzes strand exchange, swapping the single-strand DNA in and displacing the partner of the complementary strand. (336 aa) |
| | rdog | Red dog mine, isoform A; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity. It is involved in the biological process described with: transmembrane transport. (1374 aa) |
| | snu | Snustorr, isoform A; ATPase activity; ATP binding. It is involved in the biological process described with: cuticle development; transmembrane transport. (808 aa) |
| | CG31121 | FI03229p; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport. (911 aa) |
| | CG11069 | LD11139p; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport. (604 aa) |
| | spas | Spastin; ATP-dependent microtubule severing protein. Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle. Regulates microtubule stability in the neuromuscular junction synapse. Involved in lipid metabolism by regulating the size and distribution of lipid droplets. Involved in axon regeneration by regulating microtubule severing. Belongs to the AAA ATPase family. Spastin subfamily. (758 aa) |
| | Rpt5 | Regulatory particle triple-A ATPase 5 (Rpt5) encodes a component of the 26S proteasome, which degrades polyubiquitinated proteins in the cytoplasm and nucleus. (428 aa) |
| | bor | ATPase family AAA domain-containing protein 3A homolog; Required to maintain the proper number of mitochondria in neurons and muscles. (604 aa) |
| | Hmt-1 | Heavy metal tolerance factor 1; It is involved in the biological process described with: heme transport; transmembrane transport; response to cadmium ion. (866 aa) |
| | obe | Obelus (obe) encodes a Ski2-family helicase that regulates alternative mRNA splicing of crb. It is required for cell polarity and adherens junction organization. (2183 aa) |
| | CG31793 | LD28489p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. (1307 aa) |
| | CG4701 | FI08533p; ATP binding; Belongs to the AAA ATPase family. (384 aa) |
| | Orc5 | Origin recognition complex subunit 5; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity). (460 aa) |
| | RfC3 | Replication factor C subunit 3; ATP binding; DNA clamp loader activity. It is involved in the biological process described with: leading strand elongation; DNA repair; sister chromatid cohesion; DNA-dependent DNA replication. (332 aa) |
| | CG4908 | RH68195p; ATP binding. It is involved in the biological process described with: mitochondrial respiratory chain complex III assembly; protein insertion into mitochondrial inner membrane from matrix; Belongs to the AAA ATPase family. (431 aa) |
| | CG7806 | LD42916p; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport. (1487 aa) |
| | CG11147 | RH61964p; ATPase activity; ATP binding. It is involved in the biological process described with: transmembrane transport. (711 aa) |
| | CG4822 | FI05267p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. (677 aa) |
| | CG17646 | SD03967p; ATPase activity; ATP binding; ATPase-coupled transmembrane transporter activity. It is involved in the biological process described with: triglyceride metabolic process; transmembrane transport. (766 aa) |
| | CG9664 | Uncharacterized protein, isoform A; ATPase activity; ATP binding; ATPase-coupled transmembrane transporter activity. It is involved in the biological process described with: olfactory behavior; transmembrane transport. (609 aa) |
| | CG9663 | GH24286p; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity. It is involved in the biological process described with: transmembrane transport. (808 aa) |
| | cutlet | Cutlet; DNA binding; DNA clamp loader activity; ATP binding. It is involved in the biological process described with: positive regulation of DNA-directed DNA polymerase activity. (993 aa) |
| | Rpt6 | 26S proteasome regulatory subunit 8; Regulatory particle triple-A ATPase 6 (Rpt6) encodes a subunit of the proteasome, which is responsible for the ATP-dependent degradation of obsolete or damaged proteins. Rpt6 product belongs to the heterohexameric ring formed by triple-A ATPases that unfolds ubiquitinated target proteins before their degradation. (405 aa) |
| | Srp54k | Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (508 aa) |
| | CG10226 | Uncharacterized protein, isoform A; Efflux transmembrane transporter activity; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity; ATPase-coupled xenobiotic transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; xenobiotic transport. (1320 aa) |
| | Mdr65 | Multidrug resistance protein homolog 65; Multi drug resistance 65 (Mdr65) encodes a member of the MRP/ABCC subfamily of ATP-binding cassette (ABC) transporters. It is involved in humoral/CNS barrier drug exclusion and response to insecticide; Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. (1302 aa) |
| | Cdc6 | Cell division control protein; Cdc6 (Cdc6) encodes an essential component of the pre-Replication complex (preRC) together with the origin recognition complex, the product of dup and MCM2-7 proteins. The preRC is present at all chromosomal origins of replication and is required for the initiation of DNA replication. The product of Cdc6 also functions in the co-ordination of DNA replication with mitosis, and may contribute to apoptosis and transcription; Belongs to the CDC6/cdc18 family. (662 aa) |
| | Mcm7 | DNA replication licensing factor Mcm7; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (720 aa) |
| | pix | Pixie, isoform A; Pixie (pix) encodes ABCE1, which is an ATPase that functions as a translation recycling factor. It is required for the assembly of complexes involved in translation initiation, and plays a role in the regulation of cellular and organismal growth. (611 aa) |
| | CG32091 | FI02074p; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity. It is involved in the biological process described with: transmembrane transport. (623 aa) |
| | Pex1 | Peroxin 1 (Pex1) encodes a member of the family of AAA-ATPases required for peroxisome assembly. Pex1 loss results in disorganization of neurons and glia and embryonic lethality. Larval escapers exhibit developmental delay, poor feeding and uncoordinated locomotion. (1006 aa) |
| | ATPsynbetaL | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (622 aa) |
| | st | Protein scarlet; Part of a membrane-spanning permease system necessary for the transport of pigment precursors into pigment cells responsible for eye color. Scarlet and white complex transports a metabolic intermediate (such as 3-hydroxy kynurenine) from the cytoplasm into the pigment granules. (666 aa) |
| | CG6512 | SD01613p; Metalloendopeptidase activity; zinc ion binding; ATP binding. It is involved in the biological process described with: protein-containing complex assembly; cristae formation; mitochondrial protein processing; proteolysis; mitochondrial fusion. (826 aa) |
| | CG6052 | Uncharacterized protein. (1700 aa) |
| | rept | RuvB-like helicase 2; Acts as a transcriptional coactivator in Wg signaling caused by altered arm signaling. Pont and rept interfere antagonistically with nuclear arm signaling function, and are required to enhance or reduce arm activity, respectively. Also an essential cofactor for the normal function of Myc; required for cellular proliferation and growth. (481 aa) |
| | CG9330 | FI01412p; ATPase activity; ATP binding. (708 aa) |
| | Dhc16F | Dynein light intermediate chain binding; ATP binding; ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding. It is involved in the biological process described with: microtubule-based movement; cilium movement. (4081 aa) |
| | CG8142 | LD35209p; ATP binding; DNA clamp loader activity. It is involved in the biological process described with: DNA-dependent DNA replication; DNA repair. (353 aa) |
| | CG9281 | LD02975p; ATP binding; ATPase activity. (611 aa) |
| | comt | Vesicle-fusing ATPase 1; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin; Belongs to the AAA ATPase family. (745 aa) |
| | CG1824 | GH19726p; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport. (761 aa) |
| | SrpRalpha | Signal recognition particle receptor subunit alpha homolog; Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system (By similarity). May have a role in axonogenesis. (614 aa) |
| | RfC4 | Replication factor C subunit 2; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. Subunit 2 binds ATP. (331 aa) |
| | CG12010 | Uncharacterized protein; ATPase activity; ATP binding. (717 aa) |
| | ABCB7 | ATP binding cassette subfamily B member 7 (ABCB7) encodes a transporter that likely dimerizes to form a functional transporter. It may act in the mitochondria to transport substrates necessary for the maturation of ICS proteins, which are involved in iron homeostasis. (743 aa) |
| | Orc4 | Origin recognition complex subunit 4 (Orc4) encodes is a subunit of the hetero-hexameric origin recognition complex (ORC). The ORC binds to origins of DNA replication and scaffolds assembly of a pre-replicative complex, which is required for the initiation of DNA replication. At other loci, the ORC is required for heterochromatin formation. (459 aa) |
| | bw | Brown (bw) encodes a member of the traffic ATPase (or ABC) family of membrane transporters. It is believed to heterodimerize with the product of w. bw and w are necessary to import guanine, a precursor for the red pteridine pigments, into pigment cells of the eyes, Malpighian tubules and testis sheath. (675 aa) |
| | CG10505 | Uncharacterized protein; CG10505 encodes an ABC transporter whose expression is induced by excess copper, zinc, and cadmium. It is a target of the metal-responsive transcription factor encoded by MTF-1. (1312 aa) |
| | Mcm3 | DNA replication licensing factor Mcm3; Acts as component of the Mcm2-7 complex (Mcm complex) (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribut [...] (819 aa) |
| | CG10793 | FI21292p1; ATPase activity; ATP binding; microtubule-severing ATPase activity. It is involved in the biological process described with: cytoplasmic microtubule organization. (479 aa) |
| | w | White (w) encodes a member of the ABCG2 class of transporters, transporting molecules such as cyclic GMP, biogenic amines and pigments including drosopterins and ommochromes. Mutation of w results in viable flies with white eyes. A shortened version of the gene (mini-w) has been widely used in transformation constructs as a selectable marker. (687 aa) |
| | CG3156 | LD18126p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: mitochondrial transport; transmembrane transport. (692 aa) |
